DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13996 and SAMD15

DIOPT Version :9

Sequence 1:	NP_608980.1	Gene:	CG13996 / 33842	FlyBaseID:	FBgn0031763	Length:	256	Species:	Drosophila melanogaster
Sequence 2:	NP_001010860.1	Gene:	SAMD15 / 161394	HGNCID:	18631	Length:	674	Species:	Homo sapiens

Alignment Length:	279	Identity:	50/279 - (17%)
Similarity:	90/279 - (32%)	Gaps:	109/279 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 SPLPHSASGMDSPDICEPPQDEQ------EFCFRYPSYMFP---DVEYDKEDVPLPFKA------ 63
            :|.|...:|...|....|..:|:      |.....|....|   .||:.|||.|.|.|:
Human   372 NPQPPEETGPVLPQEINPQVEEKTQTKPTEKILELPDETKPRETHVEFSKEDRPEPIKSKYSVGN 436

  Fly    64 -------------------------------SPDS-------------LFNL---CAAVVDSQAR 81
                                           |.:|             |.|:   |:....|:::
Human   437 DELEHREPKRGKLSLSDKFRKEYYALGSLRESEESIGTHYEFLQPLQKLLNVSEECSYSDPSESQ 501

  Fly    82 TEV--------------------------------------FKWSINDVTDWLRNFGYPEYEQTF 108
            ||:                                      ..|...:|.:|:...|:|:|::.|
Human   502 TELSEFVHEKEVVDLSQELKERVSEDDETQPEKGTELQFEHLNWDPEEVAEWISQLGFPQYKECF 566

  Fly   109 RENYIDGHKLLNLDAVALVALNVRNFEHIRHLGRGIRALYRKELQTATETKQQSEVYKTF----- 168
            ..|:|.|.||::::...|..:.:.|||.::.:.|..:.|.  |::.....:..|..|:..
Human   567 ITNFISGRKLIHVNCSNLPQMGITNFEDMKAISRHTQELL--EIEEPLFKRSISLPYRDIIGLYL 629

  Fly   169 --RARTGRRYEGLRETELL 185
              :..||.:.:.|..:|.:
Human   630 EQKGHTGIKSDSLTLSEFV 648

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13996	NP_608980.1	SAM_superfamily	85..151	CDD:301707	18/65 (28%)
CG13996	NP_608980.1	SAM	86..147	CDD:197735	17/60 (28%)
SAMD15	NP_001010860.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..448		17/75 (23%)
		ftsN	137..>310	CDD:274041
		SAM_Samd14	543..609	CDD:188929	19/67 (28%)
		SAM	544..607	CDD:197735	18/64 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	52	1.000	Domainoid score	I11485
eggNOG	1	0.900	-	-		E1_2CMVG
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0009897
OrthoInspector	1	1.000	-	-		otm40460
orthoMCL	1	0.900	-	-		OOG6_109459
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.800