DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Gal and BGAL9

DIOPT Version :9

Sequence 1:	NP_608978.2	Gene:	Gal / 33839	FlyBaseID:	FBgn0001089	Length:	672	Species:	Drosophila melanogaster
Sequence 2:	NP_565755.1	Gene:	BGAL9 / 817842	AraportID:	AT2G32810	Length:	887	Species:	Arabidopsis thaliana

Alignment Length:	797	Identity:	196/797 - (24%)
Similarity:	307/797 - (38%)	Gaps:	222/797 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 VMALTVGLCVG---LSGDTDAPEEQPRFTIDHEANTFMLDGQPFRYVSGSFHYFRAVPESWRSRL 83
            :::|.:.|.|.   |||....|     |.:.::....::.|:....||...||.||.||.|...:
plant    14 ILSLIIALLVYFPILSGSYFKP-----FNVSYDHRALIIAGKRRMLVSAGIHYPRATPEMWSDLI 73

  Fly    84 RTMRASGLNALDTYVEWSLHNPHDGEYNWEGIADVVKFLEIAQEEDFYIILRPGPYICAERDNGG 148
            ...:..|.:.:.|||.|:.|.|..|:||:||..|:|||:::......|:.||.|||:|||.:.||
plant    74 AKSKEGGADVVQTYVFWNGHEPVKGQYNFEGRYDLVKFVKLIGSSGLYLHLRIGPYVCAEWNFGG 138

  Fly   149 LPHWLFTKYPSIKMRTNDPNYISEVGKWYAELMPRLQH--LFVGNGGKIIMVQVENEYGDYACDH 211
            .|.|| ...|.|:.||::..:..|:.|:..:::..::.  ||...||.|||:|:||||||....:
plant   139 FPVWL-RDIPGIEFRTDNEPFKKEMQKFVTKIVDLMREAKLFCWQGGPIIMLQIENEYGDVEKSY 202

  Fly   212 -----DYLNWLRDETEKYVSGKALLFTVDIPNEKMSCGKI---ENVFATTDFGIDRINEIDKIWA 268
                 ||:.|        .:..||.....:|  .:.|.:.   ||:       ||..|..
plant   203 GQKGKDYVKW--------AASMALGLGAGVP--WVMCKQTDAPENI-------IDACNGY----- 245

  Fly   269 MLRALQP---TGPLVNSEFYPGWLTHWQEQNQRRDGQEVANALRTILSYNASV-NLYMFFGGTNF 329
            .....:|   |.|::.:|.:.||.|.|......|..:::|.|:........|. |.||:||||||
plant   246 YCDGFKPNSRTKPVLWTEDWDGWYTKWGGSLPHRPAEDLAFAVARFYQRGGSFQNYYMYFGGTNF 310

  Fly   330 GFTAGANYNLDGGIGYAADITSYDYDAVMDEAG-------------------------------- 362
            |.|:|..:.          ||||||||.:||.|
plant   311 GRTSGGPFY----------ITSYDYDAPLDEYGLRSEPKWGHLKDLHAAIKLCEPALVAADAPQY 365

  Fly   363 ---------------GVT-------------------TKYNLVKAVIGEFLPLP----------- 382
                           |.|                   .|:|      |:...||
plant   366 RKLGSKQEAHIYHGDGETGGKVCAAFLANIDEHKSAHVKFN------GQSYTLPPWSVSILPDCR 424

  Fly   383 EITLNPAK-------------RLAYGRVELTPKLTL---LSTEGRAALSKGDPVESIKPKTF--- 428
            .:..|.||             |.:.|.:.:..|:..   :|...::.::..:|:.......|
plant   425 HVAFNTAKVGAQTSVKTVESARPSLGSMSILQKVVRQDNVSYISKSWMALKEPIGIWGENNFTFQ 489

  Fly   429 ---EELDL---YSGLVLYETELPSMDLDPALLK---------IDQINDRAHVFVDQELVGTLSRE 478
               |.|::   .|..:.::|.:...:.|.:..|         ||.:.|...|||:::|.|::...
plant   490 GLLEHLNVTKDRSDYLWHKTRISVSEDDISFWKKNGPNSTVSIDSMRDVLRVFVNKQLAGSIVGH 554

  Fly   479 --AQIYSLPLSKGWGSTLQLLVENQGRVNF--YISNDTKGIFGEVSLQLHNGGYLPL--ENWRST 537
              ..:..:...:| .:.|.||.:..|..|:  ::..|..|..|:..|.....|.|.|  .:| :.
plant   555 WVKAVQPVRFIQG-NNDLLLLTQTVGLQNYGAFLEKDGAGFRGKAKLTGFKNGDLDLSKSSW-TY 617

  Fly   538 AFPLEQSAVELWRREHTDEKALDPLLARQRILRNGPILYTGSLTVTE----VGDTYLNMAGWGKG 598
            ...|:..|.:::..|| :|||....|....    .|.::....|..:    .....||:...|:|
plant   618 QVGLKGEADKIYTVEH-NEKAEWSTLETDA----SPSIFMWYKTYFDPPAGTDPVVLNLESMGRG 677

  Fly   599 VAYVNGFNLGRYWPVAG--------------------------PQVTLY-VPNEILKVGENSLVI 636
            .|:|||.::||||.:..                          |..|.| ||...||...|.||:
plant   678 QAWVNGQHIGRYWNIISQKDGCDRTCDYRGAYNSDKCTTNCGKPTQTRYHVPRSWLKPSSNLLVL 742

  Fly   637 LEYQRAN------KTAT 647
            .|....|      ||.|
plant   743 FEETGGNPFKISVKTVT 759

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gal	NP_608978.2	Glyco_hydro_35	54..376	CDD:279624	111/401 (28%)
Gal	NP_608978.2	BetaGal_dom4_5	<570..637	CDD:290101	24/97 (25%)
BGAL9	NP_565755.1	PLN03059	37..877	CDD:166698	188/769 (24%)
		Glyco_hydro_35	44..348	CDD:279624	107/336 (32%)
		BetaGal_dom4_5	640..>689	CDD:290101	12/52 (23%)
		Gal_Lectin	799..876	CDD:280328
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1874
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D179316at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820