Protein Alignment eIF4A and CG14443

DIOPT Version :10

• Sequence 1: NP_476595.1
• Gene: eIF4A / 33835
• FlyBaseID: FBgn0001942
• Length: 403
• Species: Drosophila melanogaster
• Sequence 2: NP_572330.2
• Gene: CG14443 / 31595
• FlyBaseID: FBgn0029880
• Length: 736
• Species: Drosophila melanogaster
• Alignment Length: 426
• Identity: 94/426 - (22%)
• Similarity: 185/426 - (43%)
• Gaps: 51/426 - (11%)

  Fly    23 STW----HEVYDN--------------------------FDDMNLREELLRGIYGYGFEKPSAIQ 57
            :||    .|||:|                          |:.......:|:.:...|::.|:.||
  Fly   293 NTWKQPMDEVYNNAANYRKRHNITLTSWNMRNLPEPVLSFERSGFNATILQQLEDQGYDGPTPIQ 357

  Fly    58 QRAIIPCVRGRDVIAQAQSGTGKTATFSIAILQQIDTSIRECQ------ALILAPTRELATQIQR 116
            .:.......|::::..:..|||||..:.:..:.::.......|      .|||...||.|..:||
  Fly   358 AQTWSIAKEGKNIVMISGKGTGKTLGYLLPGIMKMHNQRGLMQHKKGPIVLILVDCREAAVMVQR 422

  Fly   117 VVMALGEYMKVHSHACIGGTNVREDARILESGCHVVVGTPGRVYDMINRK--VLRTQYIKLFVLD 179
            .|:.....:::.:|..:|.:..:..|.     |.::|.:.||:..||:.|  |:..:.....|||
  Fly   423 EVLYYTNPLELRTHCLLGNSQWQGHAE-----CDLLVASAGRLLQMIDNKKHVVELERCTYLVLD 482

  Fly   180 EADEMLSRGFKDQIQDVFKMLPPDVQVILLSATMPPDVLEVSRCFMRDPVSILVKKEE---LTLE 241
            ..|.|:..|.:..|..:...|.|..|:|:.|.:...::..::..|:....:|.|.:..   :.|:
  Fly   483 NIDRMIDVGLEGNICRLLCRLRPHAQLIVSSTSWSSNLKRMANKFLGQYTAIRVGEINNIGVRLQ 547

  Fly   242 GIKQ--FYVN-VKQENWKLGTLCDLYDTLSITQSVIFCNTRRKVDQLTQEMSIHNFTVSAMHGDM 303
            .|:|  ..|| :.:....:..|..:|||..|...|:....|:||.:...::..:......:||..
  Fly   548 NIRQRVEVVNGLSKVERLMKELTAIYDTSDIPGKVVIYVKRQKVVEELVDLIRNCVPCEGIHGGR 612

  Fly   304 EQRDREVIMKQFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPSNRENYIHRIGRGG--RFGRK 366
            ..::.:.|:..|.:|:..:::.|.:.:..:||..:..|||||.|.|.:.|:.|:.|.|  .:.|.
  Fly   613 TAQENQGIIHDFGTGAYNIIVATQMTSNCLDVPGIRYVINYDFPDNIDKYVQRMSRTGCLSYNRN 677

  Fly   367 GVAINFITDDDRRILKDIEQFYHTTIEEMPANIADL 402
            ...|:|.|..:.:::.::..|.....:|:..::..|
  Fly   678 CEVISFFTMANYKLVTEVVDFLKICKQEIGPHLLQL 713

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF4A	NP_476595.1	DEAD-like_helicase_N	6..403	CDD:475120	94/426 (22%)
CG14443	NP_572330.2	DEAD-like_helicase_N	<310..720	CDD:475120	88/409 (22%)