Protein Alignment CG11147 and ABCB11

DIOPT Version :10

• Sequence 1: NP_608954.1
• Gene: CG11147 / 33803
• FlyBaseID: FBgn0031734
• Length: 711
• Species: Drosophila melanogaster
• Sequence 2: XP_011510380.1
• Gene: ABCB11 / 8647
• HGNCID: 42
• Length: 1355
• Species: Homo sapiens
• Alignment Length: 339
• Identity: 86/339 - (25%)
• Similarity: 140/339 - (41%)
• Gaps: 76/339 - (22%)

  Fly     4 VEVRNGYKYYGSKSNPKIVLNQLNMNVMRGSIYGLLGASGCGKTTLLSCIVGQRRLNGGEVVVLG 68
            :|..|...:|.|:...|| ||.|||.:..|.:..|:|.||.||:|.|..|  ||..:..|.:|.
Human   454 IEFHNVTFHYPSRPEVKI-LNDLNMVIKPGEMTALVGPSGAGKSTALQLI--QRFYDPCEGMVT- 514

  Fly    69 AKPGEPGSGVPGSRVGFMPQEIALVEE------MTVKETIFYFGRIYGLTDERIREKFKLLKE-- 125
                ..|..:....:.::..:|.:||:      .|:.|.|     .||..|..:.:..:..||
Human   515 ----VDGHDIRSLNIQWLRDQIGIVEQEPVLFSTTIAENI-----RYGREDATMEDIVQAAKEAN 570

  Fly   126 ----LLQLPPARQMI-----KQCSGGQQRRLSFACAMIHDPELLILDEPTVGLDPMLREKIWDFL 181
                ::.||.....:     .|.||||::|::.|.|:|.:|::|:||..|..||......:.:.|
Human   571 AYNFIMDLPQQFDTLVGEGGGQMSGGQKQRVAIARALIRNPKILLLDMATSALDNESEAMVQEVL 635

  Fly   182 VETTRNSKL----AVIITTHYIEEAKQANCIGLMRNGVLLAEDTPTNIMIKFGTQSIEDAFLILS 242
                  ||:    .:|...|.:...:.|:.|....:|..:...|...::.:.|....    |:..
Human   636 ------SKIQHGHTIISVAHRLSTVRAADTIIGFEHGTAVERGTHEELLERKGVYFT----LVTL 690

  Fly   243 QRQGN------------EDEL---------------AQIMDHNKNQALPAAVLPP-EVID---TH 276
            |.|||            ||::               |.|...:|:|.......|| .|:|   |:
Human   691 QSQGNQALNEEDIKDATEDDMLARTFSRGSYQDSLRASIRQRSKSQLSYLVHEPPLAVVDHKSTY 755

  Fly   277 EPNMPEKQPIPFEE 290
            |.:..:|. ||.:|
Human   756 EEDRKDKD-IPVQE 768

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11147	NP_608954.1	CcmA	4..245	CDD:440746	67/261 (26%)
		ABC2_membrane_3	322..702	CDD:463674
		YadH	513..710	CDD:440604
ABCB11	XP_011510380.1	PTZ00265	52..1348	CDD:240339	86/339 (25%)
		MdlB	773..1350	CDD:440747