Protein Alignment CG11147 and Mdr49

DIOPT Version :10

• Sequence 1: NP_608954.1
• Gene: CG11147 / 33803
• FlyBaseID: FBgn0031734
• Length: 711
• Species: Drosophila melanogaster
• Sequence 2: NP_523724.2
• Gene: Mdr49 / 36428
• FlyBaseID: FBgn0004512
• Length: 1302
• Species: Drosophila melanogaster
• Alignment Length: 704
• Identity: 140/704 - (19%)
• Similarity: 235/704 - (33%)
• Gaps: 243/704 - (34%)

  Fly    22 VLNQLNMNVMRGSIYGLLGASGCGKTTLLSCI-------VGQRRLNGGEVVVLGAKPGEPGSGVP 79
            :|..|.::|:.|.....:|||||||:||:..:       .|..:|:|.::..|..       |..
  Fly   419 ILKGLTVDVLPGQTVAFVGASGCGKSTLIQLMQRFYDPEAGSVKLDGRDLRTLNV-------GWL 476

  Fly    80 GSRVGFMPQEIALVEEMTVKETIFYFGRIYGLTDERIREKFKLLK---ELLQLP-----PARQMI 136
            .|::|.:.||..|. ..|:.|.|.| || ...|...|.:..:...   .:.:||     ...:..
  Fly   477 RSQIGVVGQEPVLF-ATTIGENIRY-GR-PSATQADIEKAARAANCHDFITRLPKGYDTQVGEKG 538

  Fly   137 KQCSGGQQRRLSFACAMIHDPELLILDEPTVGLDPMLREKIWDFLVETTRNSKLAVIITTHYIEE 201
            .|.||||::|::.|.|::..|::|:|||.|..|||...:::...|...::..  ..::..|.:..
  Fly   539 AQISGGQKQRIAIARALVRQPQVLLLDEATSALDPTSEKRVQSALELASQGP--TTLVVAHRLST 601

  Fly   202 AKQANCIGLMRNGVLLAEDTPTNIMIKFGTQSIEDAFLILSQRQGNEDELAQIMDH--NKNQALP 264
            ...|:.|..:::||:..:.|...:|.:.|...  :...|..:::..|.:...:...  .|:|.|.
  Fly   602 ITNADKIVFLKDGVVAEQGTHEELMERRGLYC--ELVSITQRKEATEADEGAVAGRPLQKSQNLS 664

  Fly   265 AAVLPPEVIDTHEPNMPEKQP----------IPFEEPLNENRKKIFFTTKGRVKALMTK-NFVQL 318
            ......:..|..|...||.|.          ..........|:|     |.:.|.:::| :|.||
  Fly   665 DEETDDDEEDEEEDEEPELQTSGSSRDSGFRASTRRKRRSQRRK-----KKKDKEVVSKVSFTQL 724

  Fly   319 FRQPS---------GIIFML---LFPIIQLTCFYLAIGKTPTNLEIGVYSGEVENYGECFDENLV 371
            .:..|         ||..::   .||:                  .|::      :|:.|.
  Fly   725 MKLNSPEWRFIVVGGIASVMHGATFPL------------------WGLF------FGDFFG---- 761

  Fly   372 TVYKDSDNE---------SCLF----------NKLSCRYIRVLGDDVATRKYYASEADALNDAKR 417
             :..|.|::         |.:|          |.|........|..:.||.           .||
  Fly   762 -ILSDGDDDVVRAEVLKISMIFVGIGLMAGLGNMLQTYMFTTAGVKMTTRL-----------RKR 814

  Fly   418 A--TTVGYLHFAQNFSDSILSVMEDGIHSSDGAVDHAELSIHIDMTDQQVAYFMQRKLRDKFSTF 480
            |  |.:|                                        |.:|||...  |:.....
  Fly   815 AFGTIIG----------------------------------------QDIAYFDDE--RNSVGAL 837

  Fly   481 MRSVVKDC-NVSTAIVDLPVQFQEPIFGSTDIEFQQYCAPGVVMTMVFFLATLMTAAVFISERMD 544
            ...:..|| ||.               |:|...         |.||:..:|||:
  Fly   838 CSRLASDCSNVQ---------------GATGAR---------VGTMLQAVATLV----------- 867

  Fly   545 GIWDRTLLAGVSATEMLWAHLLTQLIIMALQSFEVIMYIGLVFDTYNNGDTTTLIGLLTLTAFCG 609
                                              |.|.:|.||....     ||:.|:||...|.
  Fly   868 ----------------------------------VGMVVGFVFSWQQ-----TLLTLVTLPLVCL 893

  Fly   610 MLF--GLFISVFCK----SHTEANFVATGAFYPMIILCGLLWPLESMPQFLQDL 657
            .::  |.||....:    |..||:.||..|...:..:.||....:.:.|::|.:
  Fly   894 SVYLEGRFIMKSAQKAKASIEEASQVAVEAITNIRTVNGLCLERQVLDQYVQQI 947

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11147	NP_608954.1	CcmA	4..245	CDD:440746	60/237 (25%)
		ABC2_membrane_3	322..702	CDD:463674	63/376 (17%)
		YadH	513..710	CDD:440604	30/151 (20%)
Mdr49	NP_523724.2	MdlB	44..643	CDD:440747	60/237 (25%)
		MdlB	720..1299	CDD:440747	66/384 (17%)