Protein Alignment CG11147 and Abca15

DIOPT Version :10

• Sequence 1: NP_608954.1
• Gene: CG11147 / 33803
• FlyBaseID: FBgn0031734
• Length: 711
• Species: Drosophila melanogaster
• Sequence 2: NP_796187.2
• Gene: Abca15 / 320631
• MGIID: 2388709
• Length: 1668
• Species: Mus musculus
• Alignment Length: 809
• Identity: 172/809 - (21%)
• Similarity: 330/809 - (40%)
• Gaps: 189/809 - (23%)

  Fly     2 AAVEVRNGYKYYGSKSNPKIVLNQLNMNVMRGSIYGLLGASGCGKTTLLSCIVGQRRLNGGEVVV 66
            |.:::::.:|.:...:..|:.:..|::|:..|.:..|||.:|.||:|.||.:.|......||..|
Mouse   520 AGIQIKHLHKVFQKNNTTKVAIKDLSLNLYEGQVTVLLGHNGAGKSTTLSILSGLYPPTSGEAYV 584

  Fly    67 LGAKPGEPGSGVPGSRVGFMPQEIALVEEMTVKETIFYFGRIYGLTDERIREKFKLLKELLQLPP 131
            .|....:....|..| :|..||:..|.:.:||.|.::::.||.|:..:      ..|:|...:..
Mouse   585 HGEDISQHMDQVRNS-LGLCPQQNLLFDHLTVSEHLYFYCRIKGVPQK------MYLEETNNMLS 642

  Fly   132 ARQMIKQC-------SGGQQRRLSFACAMIHDPELLILDEPTVGLDPMLREKIWDFLVETTRNSK 189
            |..::::|       |||.:|:|:...|:|...::.||||||.|:||..|...||.| :|.:.::
Mouse   643 AFNLMEKCDAFSKSLSGGMKRKLAIIIALIGGSKVAILDEPTSGMDPASRRSTWDIL-QTYKQNR 706

  Fly   190 LAVIITTHYIEEAK-QANCIGLMRNGVLLAEDTPTNIMIKFGTQS----IEDAFLILSQRQGNED 249
             .:::||||::||. ..:.|.:|..|.|....:...:...:|..|    :::.:.
Mouse   707 -TILLTTHYMDEADVLGDRIAIMVRGTLRCCGSSVFLKRLYGVGSHLVMVKEPYC---------- 760

  Fly   250 ELAQIMDHNKNQALPAAVLPPEVIDTHEPN-----MPEKQPIPFE---EPLNENRKKIFFTTKGR 306
            ::|:|      ..|..:.:|...::|:..|     :|::....||   ..|.||::.:..::.|.
Mouse   761 DIAEI------SKLIHSYVPTATLETNVGNELSFILPKEYTHRFEALFTALEENQENLGISSFGV 819

  Fly   307 VKALMTKNFVQLFRQPSGIIFMLLFPIIQLTCFYLAIGKTPTNLEI---------GVYSGEVENY 362
            ....|.:.|:::..                      :..:.|::|.         |..:|:||:.
Mouse   820 SITTMEEVFLKVSN----------------------LEDSKTDIEATQSPSVGSKGNKNGDVESS 862

  Fly   363 G------ECFDENLVTVYKDSDNESC---------------LFNKLSCR--YIRVLGDDVAT--- 401
            |      :..|:|:|.      |..|               ::|..:.|  .:::||..::|
Mouse   863 GRVGFPTQSEDQNIVF------NTGCSLYLQQFRAMFMKRLMYNWRNWRGILVQILGLIISTFLL 921

  Fly   402 ---RKYYASEADALN-DAKRATTVGYLHFAQ-NFSDSILSVMED----GIH-------------- 443
               .::...:...:| |....|.|.:..:.: |.:.|:|:.:|:    |.|
Mouse   922 LKSHEFRYKKIRQMNLDEYGQTIVPFSIWGKSNLTSSLLTHLENMLKPGNHQLKEVQGDLLKYLE 986

  Fly   444 SSDGAVDHAELSIHIDMTDQQV---------AYF---MQRKLRDKFSTFMRSVVKDCNVSTAIVD 496
            .:|..|....:::.|.:...:|         ||.   :...:.|.. .||.....|.:::.....
Mouse   987 GNDECVHLCVIALSIKVVANRVNLTVLFNNEAYHSPSLSLTVLDNI-LFMSLSGSDASITVFNKP 1050

  Fly   497 LPVQFQEPIFGSTDIEFQQYCAPGVVMTMVFFLATLMTAAVF----ISERMDGIWDRTLLAGVSA 557
            .|...::...||||         |.::.....|...:..:.|    ::||.:.......|:|||.
Mouse  1051 QPSPQRKEWPGSTD---------GKIVAFKIQLGMALLVSGFCILTVTERHNKTKHMQFLSGVSI 1106

  Fly   558 TEMLWAHLLTQLIIMALQ-SFEVIMYIGLVFDTYNNGDTTTLIGLLTLTAFCGMLFG-------- 613
            .....:.|:..|||..:. .|.::|:....||.|.. |...|..:|.||     |||
Mouse  1107 LVYWLSALVFDLIIFFISCCFLLVMFKYCKFDIYVT-DYHILDTMLILT-----LFGWSAIPLTY 1165

  Fly   614 LFISVFCKSHTEANFVATGAFYPMIILCGLLWPLESMPQFLQDLVMVLPF-TIPSISARNVIEKG 677
            |...:|.||::        |:..:::.|.|...|    ..|.|.::.... ||.|.|.:..:..
Mouse  1166 LLSFLFSKSNS--------AYINLLVFCYLSGTL----SLLMDTIIEARISTIMSNSTQTFLLN- 1217

  Fly   678 WSITHEKVYNGFLVMAGWTIIF--FVLCL 704
             ::....:||....::.:|:|:  .:||:
Mouse  1218 -ALLLFPMYNLGKCISEYTVIYRKKMLCI 1245

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11147	NP_608954.1	CcmA	4..245	CDD:440746	68/252 (27%)
		ABC2_membrane_3	322..702	CDD:463674	86/465 (18%)
		YadH	513..710	CDD:440604	46/208 (22%)
Abca15	NP_796187.2	rim_protein	<108..1665	CDD:130324	172/809 (21%)