Protein Alignment CG11147 and Abca4

DIOPT Version :10

• Sequence 1: NP_608954.1
• Gene: CG11147 / 33803
• FlyBaseID: FBgn0031734
• Length: 711
• Species: Drosophila melanogaster
• Sequence 2: XP_063138015.1
• Gene: Abca4 / 310836
• RGDID: 1309445
• Length: 2312
• Species: Rattus norvegicus
• Alignment Length: 1010
• Identity: 206/1010 - (20%)
• Similarity: 330/1010 - (32%)
• Gaps: 356/1010 - (35%)

  Fly     6 VRNGYKYYGSKSNPKIVLNQLNMNVMRGSIYGLLGASGCGKTTLLSCIVGQRRLNGGEVVVLGAK 70
            |:|..|.:...|.|.:  ::||:......|...||.:|.||||.||.:.|......| .|::|.|
  Rat   931 VKNLVKVFEPGSRPAV--DRLNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSG-TVLIGGK 992

  Fly    71 PGEPGSGVPGSRVGFMPQEIALVEEMTVKETIFYFGRIYGLTDERIREKFKLLKELLQLPPAR-Q 134
            ..|.........:|..||...|...:||.|.|.::.::.|.:.|..|.:.:.:.|...|...| :
  Rat   993 DIEISLDAVRQSLGMCPQHNILFHHLTVAEHILFYAQLKGRSWEEARLEMEAMLEDTGLHHKRNE 1057

  Fly   135 MIKQCSGGQQRRLSFACAMIHDPELLILDEPTVGLDPMLREKIWDFLVETTRNSKLAVIITTHYI 199
            ..:..|||.||:||.|.|.:.|.::::|||||.|:||..|..|||.|::  ..|...:|::||::
  Rat  1058 EAQDLSGGMQRKLSVAIAFVGDSKVVVLDEPTSGVDPYSRRSIWDLLLK--YRSGRTIIMSTHHM 1120

  Fly   200 EEAK-QANCIGLMRNGVLLAEDTPTNIMIKFGT----QSIEDAFLILSQRQGNE----------- 248
            :||. ..:.|.::..|.|....||..:...|||    ..:.....|.|||.|.|
  Rat  1121 DEADLLGDRIAIISQGRLYCSGTPLFLKNCFGTGFYLTLVRKMKNIQSQRCGCEGACSCTSKGFS 1185

  Fly   249 -------DELA--QIMD-----------HNKNQALPAAVLPPEVIDTHEPNMPEKQ--------- 284
                   ||:.  |::|           |:..:|.....:..|:|.. .||...||
  Rat  1186 ARCPARVDEITEEQVLDGDVKELTDLVYHHVPEAKLVECIGQELIFL-LPNKNFKQRAYASLFRE 1249

  Fly   285 ----------------PIPFEE----------------------------------PLNENRKK- 298
                            ..|.||                                  |:.::|:.
  Rat  1250 LEETLADLGLSSFGISDTPLEEIFLKVTEDSESGSKFVGGTQQKREHTGLRHPCSAPVEKHRQHA 1314

  Fly   299 --------------------------IFFTTKGR-----VKALMTKNFVQLFRQ----------P 322
                                      |.|.|..|     |:||:.|.|....|.          |
  Rat  1315 QASHTCSPGQVDPPKGQPSPEPEDPGIPFNTGARLILQHVQALLVKRFHHAVRSRKDFVAQIVLP 1379

  Fly   323 SGIIFMLL-----------FPII---------QLTCFYLAIGKTPTNLEIGVYSGEVEN---YG- 363
            :..:|:.|           ||.:         |.|.|.:   ..|.|..:.|.:..:.|   :|
  Rat  1380 ATFVFLALMLSIIVPPFGEFPALTLHPWMYGHQFTFFSM---DEPNNEHLEVLADVLLNRPGFGN 1441

  Fly   364 ECFDENLVTVY-----------KDSDNESCLFNK-----------LSC----------------- 389
            .|..|..:..|           ..|.|.:.||.|           ..|
  Rat  1442 RCLKEEWLPEYPCGNATSWKTPSVSPNITHLFQKQKWTAAHPSPACKCSTREKLIMLPECPEGAG 1506

  Fly   390 ---------RYIRVLGD-------DVATRKYYASEADAL------NDAKRATTVGYLHFAQNFSD 432
                     |...||.|       |...:.|.|....:|      |:.:    .|.:.......|
  Rat  1507 GLPPPQRIQRSTEVLQDLTNRNISDYLVKTYPALIRSSLKSKFWVNEQR----YGGISIGGKLPD 1567

  Fly   433 ---------SILSVMEDGIHSSDGAV------DHAELSIHIDMTDQQVAYFMQRK-------LRD 475
                     ..||.:...::.|.|.|      :..:...|::..|....:|..:.       |..
  Rat  1568 IPISGEALVGFLSDLGQMMNVSGGPVTRESSREMLDFLKHLETKDNIKVWFNNKGWHALVSFLNV 1632

  Fly   476 KFSTFMR-SVVKDCN---VSTAIVDLPV-----QFQEPIFGSTDIEFQQYCAPGVVMTMVFFLAT 531
            ..:..:| |:.||.:   ....::..|:     |..|....:|.|:       .||...|.|..:
  Rat  1633 AHNAILRASLPKDRDPEEYGITVISQPLNLTKEQLSEITVLTTSID-------AVVAICVIFAMS 1690

  Fly   532 LMTAA---VFISERMDGIWDRTLLAGVSATEMLWAHLLTQLIIMALQSFEVI-MYIGLVFDTYNN 592
            .:.|:   ..|.||:........::|||.|.....:.|..::..|:.:..|: ::||.....|.:
  Rat  1691 FVPASFVLYLIQERVTKAKHLQFISGVSPTTYWMTNFLWDIMNYAVSAGLVVGIFIGFQKKAYTS 1755

  Fly   593 GDT-TTLIGLLTL--------------------TAF----CGMLF-GL-------FISVFCKSHT 624
            .|. ..|:.||.|                    ||:    |..|| |:       .:.:|..:..
  Rat  1756 TDNLPALVTLLMLYGWAVIPMMYPASFLFDVPSTAYVALSCANLFIGINSSAITFVLELFENNRM 1820

  Fly   625 EANFVATGAFYPMIILCGLLWPLESMPQFLQDLVMVLP-FTIPSISARNVIEKGWSITHEKVYNG 688
            ...|.||                      |::|::|.| |.:    .|.:|:...|.....:|..
  Rat  1821 LLRFSAT----------------------LRELLIVFPHFCL----GRGLIDLALSQAVTDIYAQ 1859

  Fly   689 F------------------LVMAGWTIIFFVLCLI 705
            |                  :.||...:::|:|.|:
  Rat  1860 FGEEYSANPFQWDLIGKNLVAMAIEGVVYFLLTLL 1894

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11147	NP_608954.1	CcmA	4..245	CDD:440746	77/244 (32%)
		ABC2_membrane_3	322..702	CDD:463674	97/551 (18%)
		YadH	513..710	CDD:440604	48/249 (19%)
Abca4	XP_063138015.1	None