Protein Alignment CG11147 and Abca5

DIOPT Version :10

• Sequence 1: NP_608954.1
• Gene: CG11147 / 33803
• FlyBaseID: FBgn0031734
• Length: 711
• Species: Drosophila melanogaster
• Sequence 2: NP_775429.1
• Gene: Abca5 / 286970
• RGDID: 628661
• Length: 1642
• Species: Rattus norvegicus
• Alignment Length: 821
• Identity: 159/821 - (19%)
• Similarity: 283/821 - (34%)
• Gaps: 270/821 - (32%)

  Fly     3 AVEVRNGYKYYGSKSNPKIVLNQLNMNVMRGSIYGLLGASGCGKTTLLSCIVGQRRLNGGEVVVL 67
            |:.:....|.|..|:.....|..|:.::..|.|..|||.||.||:||::.:.|....:.|...:.
  Rat   477 AIRISGIQKAYRKKNETVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIY 541

  Fly    68 GAKPGEPGSGVPGSR-VGFMPQEIALVEEMTVKETIFYFGRIYGL-TDERIREKFKLLKELLQLP 130
            |.:..|........: :|..||.....:.:||:|.:.....:.|: .:..|:|..|:|.:|....
  Rat   542 GHRVSEIDEMFEARKMIGICPQSDMNFDVLTVEENLSILASVKGIPANNIIQEVQKVLLDLDMQA 606

  Fly   131 PARQMIKQCSGGQQRRLSFACAMIHDPELLILDEPTVGLDPMLREKIWDFLVETTRNSKLAVIIT 195
            ......|:.||||:|:||...|::.:|::|:|||||.|:||..|..:|:.|  ..|.:....:.:
  Rat   607 IKDNQAKKLSGGQKRKLSLGIAVLGNPKILLLDEPTAGMDPCSRHIVWNLL--KYRKANRVTVFS 669

  Fly   196 THYIEEAK------------QANCIG------------------------------LMR------ 212
            ||:::||.            ...|:|                              |:|
  Rat   670 THFMDEADILADRKAVISQGMLKCVGSSIFLKSKWGIGYRLSMYIDRYCATESLSSLVRQHIPAA 734

  Fly   213 ----------------------NGVLLAEDTPTNI-MIKFGTQ--SIEDAFLILSQRQGNEDELA 252
                                  :|:..|.|..:|: :|.:|..  ::||.||.|..    |.|:.
  Rat   735 ALLQQNDQQIVYSLPFKDMDKFSGLFSALDIHSNLGVISYGVSMTTLEDVFLKLEV----EAEID 795

  Fly   253 QIMDHNKNQALPAAVLPPEVIDTHEPNMPEKQPIPFEEP------LNENRKKIFFTT---KGRVK 308
            | .|::              :.|.:|...|.....|:|.      |:|.:..:..|.   |.:|.
  Rat   796 Q-ADYS--------------VFTQQPREEETDSKSFDEMEQSLLILSETKASLVSTMSLWKQQVS 845

  Fly   309 ALMTKNFVQLFRQP----SGIIFMLLFPIIQLTCF--------------------YLAIGKTPTN 349
            .:...:|:.|.|:.    |.::.:|:|..:|:..|                    :|..|..|..
  Rat   846 TIAKFHFLSLKRESKSVRSVLLLLLIFFAVQIFMFLVHHSFKNAVVPIKLVPDLYFLKPGDKPHK 910

  Fly   350 LEIGVY-----SGEVENYGECFDEN--LVTVYKDSDNESCLFNKLSCRYIRVLGDDVATRKYYAS 407
            .:..:.     ..::.:..:.|.:.  :|.::.|||..|...:..:...::...|.|.|..:.::
  Rat   911 YKTSLLLQNSTDSDINDLIDFFTQQNIIVAMFNDSDYVSAAPHSAALNVVQSEKDYVFTAVFNST 975

  Fly   408 EADALNDAKRATTVGYLHFAQNFSDSILSVMEDGIHSSDGAVDHAELSIHIDMTDQ-QVAYFMQR 471
            ...:|.......:..||:                               |:::||. |:
  Rat   976 MVYSLPVMMNIISNYYLY-------------------------------HLNVTDTIQI------ 1003

  Fly   472 KLRDKFST-FMRSVVKDCNVSTAIVDLPVQFQEPIFGSTDIEFQQYCAPGVVMTMVFFLATLMTA 535
                 :|| |::.:                        |||.|:         ..::|.|.|:..
  Rat  1004 -----WSTPFIQEI------------------------TDIVFK---------VELYFQAALLGI 1030

  Fly   536 AVFISERMDGIWDRTLLAGVSATEMLWAHLLTQLIIMALQSFEVIMYIGLVFDTYNNGDTTTLIG 600
            .|            |.:....|.|....|        .::::..:...||:...|..|.....|.
  Rat  1031 IV------------TAMPPYFAMENAENH--------KIKAYTQLKLSGLLPSAYWIGQAVVDIP 1075

  Fly   601 L--LTLTAFCGMLFGLFISVFCKSHTEANFVATGAFYPMIILCGLLWPLESMPQFLQDLVMVLPF 663
            |  :.||...|.||.....::              |||:..|.               :|..|..
  Rat  1076 LFFVVLTLMLGSLFAFHHGLY--------------FYPVKFLA---------------VVFCLIA 1111

  Fly   664 TIPSISARNVIEKGWSITHEKVYNGFLVMAGWTIIFFVLCL 704
            .:||:.....|.   |.|.:|:.|   ....|:.|:.|..|
  Rat  1112 YVPSVILFTYIA---SFTFKKILN---TKEFWSFIYSVTAL 1146

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11147	NP_608954.1	CcmA	4..245	CDD:440746	74/315 (23%)
		ABC2_membrane_3	322..702	CDD:463674	65/414 (16%)
		YadH	513..710	CDD:440604	37/194 (19%)
Abca5	NP_775429.1	rim_protein	<107..1618	CDD:130324	159/821 (19%)