Protein Alignment CG11147 and pgp-13

DIOPT Version :10

• Sequence 1: NP_608954.1
• Gene: CG11147 / 33803
• FlyBaseID: FBgn0031734
• Length: 711
• Species: Drosophila melanogaster
• Sequence 2: NP_001359545.1
• Gene: pgp-13 / 184845
• WormBaseID: WBGene00004007
• Length: 1323
• Species: Caenorhabditis elegans
• Alignment Length: 660
• Identity: 144/660 - (21%)
• Similarity: 240/660 - (36%)
• Gaps: 176/660 - (26%)

  Fly     4 VEVRNGYKYYGSKSNPKIVLNQLNMNVMRGSIYGLLGASGCGKTTLLSCIVGQRRLNGGEVVVLG 68
            |...|.:..|.::...| |||.||:.|..|:...|:|.|||||:|.:..:........|.|.:.|
 Worm   417 VTFENVHFRYPTRKEAK-VLNGLNLTVEPGTSVALVGHSGCGKSTSVGLLTRLYEPEQGSVQIDG 480

  Fly    69 AKPGEPGSGVPGSRVGFMPQEIALVEEMTVKETIFYFGRIYGLTDERIREKFKLLKELLQLPPAR 133
            ....:.......:.||.:.||..|..: |:...:. ||......:..||        :.::..|.
 Worm   481 VDVRDLNLEWLRNVVGIVQQEPILFND-TIHNNLL-FGNPDATRETMIR--------VCKMANAH 535

  Fly   134 QMIK---------------QCSGGQQRRLSFACAMIHDPELLILDEPTVGLDPMLREKIWDFLVE 183
            ..||               |.||||::|::.|..:|.||::|:|||.|..||......:...|..
 Worm   536 DFIKKMPKGYDTQIGDGGVQLSGGQKQRVAIARTLIRDPKVLLLDEATSALDAQSESVVQSALNN 600

  Fly   184 TTRNSKLAVIITTHYIEEAKQANCIGLMRNGVLLAEDTPTNIMIKFGTQSIEDAFLILSQRQGNE 248
            .::..  ..|:..|.:...::|:.|.....||::                          ..||.
 Worm   601 ASKGR--TTIMIAHRLSTIREADKIVFFEKGVIV--------------------------EAGNH 637

  Fly   249 DELAQI----MDHNKNQALPAAVLPPEV-IDTHEPNMPEKQPIPFEEPLNENRKKIFFTTK--GR 306
            :||..:    .|..|.||....  |.|: ::..|    |.|...|::|...|||.....::  ||
 Worm   638 EELVNLGGRYFDLVKAQAFKQD--PDEIALEKEE----EDQFDEFDKPTVFNRKVSVRNSRSSGR 696

  Fly   307 V------KALMTKNFVQLFRQPSGIIFMLLFPIIQLTCFYLAIGKTPTNLEIGVYSGEVENYGEC 365
            .      :..:..:....||:.|.|      |..:...|.|.:.:|            :|..||
 Worm   697 SGSEEFRRGSLANHSFDRFRKASHI------PSAEDEAFALRVKET------------MEKDGE- 742

  Fly   366 FDENLVTVYKDSD-NESCLFNKLSCRYIRVLGDDVATRKYYASEADALNDAKRATTVGYLHFAQN 429
            .....:.::|::. |.:.:...||...||  |.|:.|   :|                 |.||..
 Worm   743 ITAGFLDIFKNAQGNYTYMLIGLSAALIR--GLDLPT---FA-----------------LLFAWV 785

  Fly   430 FSDSILSVMEDG--IHS-SDGAVDHAELSIHIDMTDQQVAYFMQRKLRDKFSTFMRSVVKDCNVS 491
            | :....|...|  :|. :...:.|....:.|        :|.|     ..||.|.::|.:
 Worm   786 F-EGFEFVPYGGKMMHRLAMSVIAHCAAGLGI--------WFFQ-----TLSTVMFAIVSE---- 832

  Fly   492 TAIVDLPVQFQEPIFGSTDIEFQQYC-----APGVVMTMVFFLATLMTAAVFISERMDGIWDRTL 551
                :|.|:|:...|.:...:...|.     |||.::|.:......:.|.|          |..:
 Worm   833 ----NLGVRFRVAAFRNLLYQDAAYFDNPAHAPGSLITRLAADPPCVKAVV----------DGRM 883

  Fly   552 LAGVSATEMLWAHLLTQLIIMALQSFEV-IMYIGLVFDTYNNGDTTTLIGLLTLTAFCGMLFGLF 615
            :..|.||    |.::..:.|..:..::| |:...|:|          |:|.:    ..|:.|.
 Worm   884 MQVVYAT----AAVIACVTIGFINCWQVAILGTALIF----------LLGFI----MAGLAFK-- 928

  Fly   616 ISVFCKSHTE 625
            ||:....|.|
 Worm   929 ISIVAAEHME 938

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11147	NP_608954.1	CcmA	4..245	CDD:440746	59/255 (23%)
		ABC2_membrane_3	322..702	CDD:463674	63/314 (20%)
		YadH	513..710	CDD:440604	25/119 (21%)
pgp-13	NP_001359545.1	MdlB	77..655	CDD:440747	65/276 (24%)
		PTZ00265	92..1317	CDD:240339	144/660 (22%)