Protein Alignment CG11147 and abt-4

DIOPT Version :10

• Sequence 1: NP_608954.1
• Gene: CG11147 / 33803
• FlyBaseID: FBgn0031734
• Length: 711
• Species: Drosophila melanogaster
• Sequence 2: NP_503175.1
• Gene: abt-4 / 178559
• WormBaseID: WBGene00000022
• Length: 1802
• Species: Caenorhabditis elegans
• Alignment Length: 829
• Identity: 170/829 - (20%)
• Similarity: 303/829 - (36%)
• Gaps: 221/829 - (26%)

  Fly     4 VEVRNGYKYYGS------------KSNPKIVLNQLNMNVMRGSIYGLLGASGCGKTTLLSCIVGQ 56
            :.|.|..|.||:            ||..|..::.||:.:..|....|||.:|.||:|..|.:.|.
 Worm   584 INVVNLTKTYGTSFFKKLFDCKFGKSGEKRAVSNLNLKMYPGQCTVLLGHNGAGKSTTFSMLTGV 648

  Fly    57 RRLNGGEVVVLGAKPGEPGSGVPGSR--VGFMPQEIALVEEMTVKETIFYFGRIYGLTDE----- 114
            ...:.|...|   ...:..:.:|..|  :|..||...|...|||.|.:.:|.::...|.:
 Worm   649 ASPSSGSAYV---NDFDIRTSLPKIRREMGLCPQYNTLFGFMTVMEHLEFFAKLKERTWDPEEAR 710

  Fly   115 ----RIREKFKLLKELLQLPPARQMIKQCSGGQQRRLSFACAMIHDPELLILDEPTVGLDPMLRE 175
                |:|..||          |..|....||||:|:||.|.|:|...|:::|||||.|:||..|.
 Worm   711 EILARLRIDFK----------ADFMAGALSGGQKRKLSLAIALIGGSEVVMLDEPTSGMDPGARH 765

  Fly   176 KIWDFLVETTRNSKLAVIITTHYIEEAK-QANCIGLMRNGVLLAEDTPTNIMIKFGTQSIEDAFL 239
            :.|. |::..:..: .:::|||::|||. ..:.|.:|.:|.|....:|                :
 Worm   766 ETWT-LIQREKERR-TILLTTHFMEEADLLGDRIAIMAHGQLECCGSP----------------M 812

  Fly   240 ILSQRQGNEDELAQIMDH------NKNQALPAAVLPPEVI-------------DTHEPNMPE--- 282
            .|.|:.|:...|..:.|.      :|...:....:|...:             .||.|..|:
 Worm   813 FLKQQYGDGYHLTIVYDTTSTPDVSKTTDIIREYIPEAHVFSYIGQEATYLLSATHRPIFPKLFK 877

  Fly   283 ----------------------------------------------KQPIPFEEP-LNENRKKI- 299
                                                          .:.|..::| |.:.|.::
 Worm   878 ELEDHQTQCGITSFGVSITTMEEVFLKVGHTADERYNYEHGIENDISEMIEKDDPILQDLRAQVR 942

  Fly   300 ---FFTTKGRVKALMTKNFVQLFRQPSGIIFMLLFPIIQLTCFYLAI-------GKTPTNLEIGV 354
               |.......||:..|..:..||:.:..:..|:||:..|.......       .:.|..:.:..
 Worm   943 VTGFTLQMQHAKAMFYKRAIFFFRKWTQFLPQLVFPVAYLVLMVFTSQVLPSVKEQDPQTISLAP 1007

  Fly   355 YSGEVENYGECFDE--NLVTVYKDSDNESCLFNKLSCRYIRVLG-----DDVAT--RKYYASEAD 410
            :| :.:..|....:  |.||:...|.|.|.:....    :..||     .|:.:  .|:...:.:
 Worm  1008 FS-DTKKAGHLVSDSGNYVTLLGGSQNLSSMVQGT----VTQLGVTQTVVDITSNVEKFIMDQTN 1067

  Fly   411 ALNDAKRATTVGYLHFAQNFSDSILSVMEDGIHSSDGAVDHAEL---SIHIDMTDQQVAYFMQRK 472
            |:.    :.|.| ||:|..|..|:.:.....:.|.....::..|   ::.|..||..:   :.:|
 Worm  1068 AMG----SRTFG-LHYALGFVPSMFNFSTVSVPSLKTFFNNFGLYTPALAITFTDSMI---LSQK 1124

  Fly   473 LRDKFSTFMRSVVKDCNVSTAI-VDLPVQFQEPIFGSTDIEFQQY-CAPGVVMTMVFFLATLMTA 535
            .:.::|            .||: ..||...|:.:..:...:...: .|.|::::  |.:.....:
 Worm  1125 QKKQYS------------FTAVNHPLPPSTQDTLKNTNRSDGAAFLIAYGLIVS--FAVCVAGYS 1175

  Fly   536 AVFISERMDGIWDRTLLAGVSATEMLWAHLLTQLI------IMALQSFEVIMYIGLVFDTYNNGD 594
            ...|:||........||:|:..    |...||..|      ::.:..|:.|.||      :|...
 Worm  1176 QFLITERKKKSKHMQLLSGIRP----WMFWLTAFIWDAAWFVIRILCFDAIFYI------FNITA 1230

  Fly   595 TTTLIGLLTLTAFCGMLFG-------LFISVFCKSHTEANFVATGAFYPMIILCGLLWPLESMPQ 652
            .|...|::.:.....:|:|       .:...|.:|..:...:.|  .|.  ||.|
 Worm  1231 YTHDFGVMLILTLSFLLYGWTALPFTYWFQFFFESAPKGFMMVT--MYH--ILTG---------- 1281

  Fly   653 FLQDLVMVLPFTIPSISARNVIEKG--WSITHEKVYNGFLVMAGWTIIF 699
                  |:....:|.||..:.::.|  |||....::..:.:....|:.|
 Worm  1282 ------MIGSIAVPIISQTSSLDAGYLWSIIFAWLFPTYNISQIATVTF 1324

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11147	NP_608954.1	CcmA	4..245	CDD:440746	75/264 (28%)
		ABC2_membrane_3	322..702	CDD:463674	76/414 (18%)
		YadH	513..710	CDD:440604	39/203 (19%)
abt-4	NP_503175.1	rim_protein	<270..1764	CDD:130324	170/829 (21%)