Protein Alignment CG11147 and Eato

DIOPT Version :10

• Sequence 1: NP_608954.1
• Gene: CG11147 / 33803
• FlyBaseID: FBgn0031734
• Length: 711
• Species: Drosophila melanogaster
• Sequence 2: XP_061496567.1
• Gene: Eato / 1281655
• VectorBaseID: AGAMI1_002735
• Length: 1669
• Species: Anopheles gambiae
• Alignment Length: 761
• Identity: 170/761 - (22%)
• Similarity: 284/761 - (37%)
• Gaps: 236/761 - (31%)

  Fly     4 VEVRNGYK-YYGSKSNPKIVLNQLNMNVMRGSIYGLLGASGCGKTTLLSCIVGQRRLNGGEVVVL 67
            |.:.|..| ::..||..|:|:....:::...||..|||.:|.||||.::.|.|......|.:||
Mosquito   504 VRIANLTKVFHSRKSGAKVVVKNFGLSIYSNSITVLLGHNGAGKTTTMNIITGMVPRTSGTIVV- 567

  Fly    68 GAKPGEPGSGVPGSRVGFMPQEIALVEEMTVKETIFYFGRIYGLTDERIREKFKLLKELLQ-LPP 131
               .||..:.....::||.||.......::..|.:.:||.:.||......::.||:.|.:. |..
Mosquito   568 ---DGEHDANRYRHKIGFCPQHDVFFSYLSCLEHLVFFGCLRGLGRVEAEKEAKLVLEKVHLLDK 629

  Fly   132 ARQMIKQCSGGQQRRLSFACAMIHDPELLILDEPTVGLDPMLREKIWDFLVETTRNSKLAVIITT 196
            :..::...|||.:||||.|.|::...:||||||||.||||..|..|||.|:...:|.  .|::||
Mosquito   630 SDALVHTLSGGMKRRLSLAIALVGATKLLILDEPTSGLDPESRRDIWDILLNLRQNH--TVLLTT 692

  Fly   197 HYIEEAK-QANCIGLMRNGVLLAEDTP-----------TNIMIKFGTQSIEDAFLILSQRQGNED 249
            |::|||. ..:.:.:|..|.|:|..:|           |..::|..|....:.:..:.|...|
Mosquito   693 HFMEEADVLGDWVAIMEEGELVAFGSPLFLKQQYGKGYTLKLLKGATFDKRETWQRIQQLIPN-- 755

  Fly   250 ELAQIMDHNKNQALPAAVLPPEVIDTHEPNMPE----KQPIPFE--EPLNENRKKIFFTTKGRVK 308
              |.:.|  ..|.:.||.||.:.|..:.|.:.|    :|.:..|  :..|...:::|..:..|.|
Mosquito   756 --ATVRD--TVQEIFAATLPYDEIRKYAPLLKELEATQQELGIETIDMANATLEEVFLNSSNRRK 816

  Fly   309 ALM----------------TKNFVQL--FRQPSGIIF---------------------------- 327
            .|.                .:|.:::  ...||.:.|
Mosquito   817 ELQHHPESVDFVDSPTSPAAENLIEIEVALHPSKLTFPEARNTFMAIWRKKWIHIKCNTHVYGWL 881

  Fly   328 MLLFPIIQLTCFYLAIGKT---------------------------------------------- 346
            .:|.|::.:.||.|..|.|
Mosquito   882 AVLPPLVTVLCFTLTSGITDAAKALPAVTLTADSIYQAFGVLVVNRGDRGDEFWDREAIQSDLDR 946

  Fly   347 -PTNLEIGVYSGEVENYG------ECFDENLVT------------VYKDSDNESCLFNKLSCRYI 392
             |.|   ||....:|||.      |..|::..|            |..|..:.:.|:|. :..:.
Mosquito   947 HPVN---GVRMMLLENYALVDALQELIDKDYTTYRDRLVVGIECNVTADGVHVAVLYNN-NLLHS 1007

  Fly   393 RVLGDDVATR---KYYASEADALNDAKRATTVGYLHFAQNFSDSILSVMEDGIHSSDGAVDHAEL 454
            ..:.:.|.|.   :|||.||||:                             :|:.:......:|
Mosquito  1008 AGIAETVTTTVLLRYYAGEADAM-----------------------------VHTRNIPSTRKQL 1043

  Fly   455 SIHIDMTDQ-------------QVAYFMQRKLRDKFSTFMRSVVKDCN-----VSTAIVDLPVQF 501
               ||:...             .|..::|..|::..|.|.:  :::.|     .||...||.:..
Mosquito  1044 ---IDIKTPYYFTELIAIAFYFYVLMYLQVPLQEHLSGFRQ--LQNINRYLYWASTYAFDLTIHL 1103

  Fly   502 QEPIFGSTDIEFQQYCAPGVVMTMVFFLATLMTAAVFISERMDGIWDRTLLA-GVSATEMLWAHL 565
            .|.:               ||:.:|..|.  .|.|...|...:..|  ||:. ||.|..::  ::
Mosquito  1104 AECL---------------VVLALVLLLD--RTDAFTESSEREIFW--TLVVYGVIALPVI--YI 1147

  Fly   566 LTQLI-----IMALQSFEVIMYIGLVF-------DTYNNGDTTTLI 599
            ::|.:     .:.:.|:.:|:.:|.||       |..||....|::
Mosquito  1148 ISQCVDNANTAITIMSYLMIVGVGGVFLLSNGYDDIKNNSGWITVL 1193

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11147	NP_608954.1	CcmA	4..245	CDD:440746	80/254 (31%)
		ABC2_membrane_3	322..702	CDD:463674	71/405 (18%)
		YadH	513..710	CDD:440604	23/100 (23%)
Eato	XP_061496567.1	None