Protein Alignment Hsp60C and CCT2

DIOPT Version :10

• Sequence 1: NP_608948.2
• Gene: Hsp60C / 33796
• FlyBaseID: FBgn0031728
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_012124.1
• Gene: CCT2 / 854664
• SGDID: S000001404
• Length: 527
• Species: Saccharomyces cerevisiae
• Alignment Length: 578
• Identity: 136/578 - (23%)
• Similarity: 244/578 - (42%)
• Gaps: 123/578 - (21%)

  Fly    32 FGPEV--------RAMMLQGVDVLADAVAVTMGPKGRNVIIEQ-SWGSPKITKDGVTVAKSIALK 87
            ||.:|        |.....|...:.|.|..|:||||.:.:::. |..:..:|.||.|:.|||.|
Yeast     6 FGDQVTEERAENARLSAFVGAIAVGDLVKSTLGPKGMDKLLQSASSNTCMVTNDGATILKSIPL- 69

  Fly    88 DKFQNIGAKLVQDVANNTNEEAGDGTTTATVLARAIAKEGFEKISRG-ASPVEIRRGVMLAIETV 151
               .|..||::.:::...::|.|||||:.|||:..:.:|..:.|.:. ..|..|..|..||....
Yeast    70 ---DNPAAKVLVNISKVQDDEVGDGTTSVTVLSAELLREAEKLIDQSKIHPQTIIEGYRLASAAA 131

  Fly   152 KDNLRRLSRPVNTP-------EEICQVA--TISA---NGDKSVGNLISEAIKKVGRDGVITVKDG 204
            .|.|.:.:  |:..       |::..:|  |:|:   :.||       :...::..:.::.:| |
Yeast   132 LDALTKAA--VDNSHDKTMFREDLIHIAKTTLSSKILSQDK-------DHFAELATNAILRLK-G 186

  Fly   205 KTLCDELEVIE--GMKFDRGYISPYFINTSK----------GAKVEF------QDALLLFCEK-K 250
            .|..:.:::|:  |.|....::...||...|          .||:..      .|.:.:|..| |
Yeast   187 STNLEHIQIIKILGGKLSDSFLDEGFILAKKFGNNQPKRIENAKILIANTTLDTDKVKIFGTKFK 251

  Fly   251 IKSAPSIVPALELANAQRKPLVIIAEDLEAEALSTLVVNR---------LKVGLQVCAVKAPGFG 306
            :.|...:.   :|..|:|:.:......:....::|. :||         |...|.:.:::...|
Yeast   252 VDSTAKLA---QLEKAEREKMKNKIAKISKFGINTF-INRQLIYDYPEQLFTDLGINSIEHADF- 311

  Fly   307 DNRKENLMDMAVATGGIVFG--DEANMVRLEDIKMSDFGRVGEVVVSKDDTMLLKGKGQKAEVEK 369
                |.:..:|:.|||.|..  ||.:..:|.:..:     :.|:::.:..  .||..|.||
Yeast   312 ----EGVERLALVTGGEVVSTFDEPSKCKLGECDV-----IEEIMLGEQP--FLKFSGCKA---- 361

  Fly   370 RVEGLREAIKESTSSYEKEKMQERLARLSSGVALLRVGGSSDVEVSEKKDRVIDALNA-TRAAVE 433
                 .||.                      ..:||  |::|..:.|.:..:.|||:. ::...|
Yeast   362 -----GEAC----------------------TIVLR--GATDQTLDEAERSLHDALSVLSQTTKE 397

  Fly   434 EGIVPGGGTALLRCIQKLNDLKGANED--QNMGIEIIRRALRMPCLTIAKNAGVDGAMVVAKV-- 494
            ...|.|||.|.: .:.|..|.:..|.|  :::.:|...||||.....:|.|||.|.:.:|:|:
Yeast   398 TRTVLGGGCAEM-VMSKAVDTEAQNIDGKKSLAVEAFARALRQLPTILADNAGFDSSELVSKLRS 461

  Fly   495 EILDG--DYGYDALKGEYGNMIERGIIDPTKVVRTAISDAAGVASLLTTAEAVVTELP 550
            .|.:|  ..|.|...|...:|.:.||::..|:.|..:|.|:..|.:|...:.::...|
Yeast   462 SIYNGISTSGLDLNNGTIADMRQLGIVESYKLKRAVVSSASEAAEVLLRVDNIIRARP 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60C	NP_608948.2	GroEL	28..548	CDD:239460	135/574 (24%)
CCT2	NP_012124.1	TCP1_beta	5..520	CDD:239452	136/578 (24%)