Protein Alignment Hsp60C and TCM62

DIOPT Version :10

• Sequence 1: NP_608948.2
• Gene: Hsp60C / 33796
• FlyBaseID: FBgn0031728
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_009600.2
• Gene: TCM62 / 852332
• SGDID: S000000248
• Length: 572
• Species: Saccharomyces cerevisiae
• Alignment Length: 595
• Identity: 117/595 - (19%)
• Similarity: 240/595 - (40%)
• Gaps: 138/595 - (23%)

  Fly    34 PEVRAMMLQGVDVLADAVA--------VTMGPKGRNVIIEQSWGS-PKITKDGVTVAKSIALKDK 89
            |..|...||   ||.|.::        :|.....:.:|.|..:.| |::.....|:        :
Yeast    24 PIYRTKNLQ---VLRDTLSGIKLLEKIITSSSYNKTLIYEPKYKSKPQVVSSHDTM--------R 77

  Fly    90 FQNIGAKLVQ----DVANNTNEEAG-------------------DGTTTATVLARAIAKEGFEKI 131
            ..|:..:|:.    |.|.||..::.                   :.|.|:|.|..::.:..|:..
Yeast    78 LHNVMRELLDSLQVDEATNTRLQSNRPRKLGRVGLQLFMDCIQDNLTATSTSLTCSLLEHYFKYP 142

  Fly   132 SRGASPVEIRRGVMLAIETVKDNLRR---LSRPVNTPEEICQVATISANGDKSVGNLISEAIKKV 193
            .:     |:..|:...:..::|.|.:   :.:..|..:.:.:..|:|::..:|:..::.....::
Yeast   143 EK-----EVTNGIKAGLRYIRDFLAKNKIIVKSQNDVDALVEQLTMSSSDSQSIKRVLKAINYEL 202

  Fly   194 GRDGVITVKDGKTLCDELEVIEGMKFDRG-------YISPYFINTSKGAKVEFQDALLLFCEKKI 251
            ..|.::.|.:|....||::|.:|.|:..|       |:....:.|.|...:: :|.|:|..:..:
Yeast   203 FSDDIVRVINGNKTYDEVDVSKGWKYPAGILDSNEAYLRSLELPTKKLVSID-KDMLVLMYDGTL 266

  Fly   252 KSAPSIVPALELANAQRKP-LVIIAEDLEAEALSTLVVNRLKVGLQVCAVKAPGFGDNRKENLMD 315
            :.|..|:|.:..|...||. |:|:..|...:||:::.:|..:               |::||...
Yeast   267 RDANKILPTITYARKLRKSVLLIVNGDCTGDALTSVTINNNR---------------NKRENNES 316

  Fly   316 MAVATGGIVFGDEAN--MVRLEDIKMSDFGRVG---EVVVSKDDTMLLKGKGQKAEVEKRVEGLR 375
            ..|.   :.:..:||  :...|::....|.|:.   :.:.|.:.:.|:..|    ....:..|..
Yeast   317 RIVV---LKYSKKANNDLAPQENLDFIKFLRLPCGYDSIYSPEYSPLVPSK----MCADKYYGSI 374

  Fly   376 EAIKEST------SSYEKEKMQERLAR-LSSGVALLRVGGSSDVEVSEKKDRVIDALNATRA-AV 432
            |:||.:|      :|.:.|.:..::.: .......|.:||.:::|:..:::.:.:.||.... .:
Yeast   375 ESIKATTGEAFLYNSIDAEAIPNKVPKSFLQNTVTLSIGGHNEIEIDRRRNAIDNCLNNVLCHGL 439

  Fly   433 EEGIVPGGGTALLRCIQKLNDLKGANEDQNM---GIEIIRRALRMPCLTIAKNAGVDGAMVVAKV 494
            .:|.:||.|.:||:.|..||:|| |||...|   ||..:..|:.:|.....|||
Yeast   440 AKGFIPGYGISLLKAIPGLNELK-ANEPNFMTKVGINAVLSAVILPSEVAFKNA----------- 492

  Fly   495 EILDGDYGYD----------------------ALKGEYGNMIERGIIDPTKVVRTAISDAAGVAS 537
                  |||:                      :...|..|.::.|.::|...:.:.::.......
Yeast   493 ------YGYNYYEINSLIAGAINEKSFPMAKFSPNSEPVNTVKDGNLEPWSKMDSCLAGVETFIE 551

  Fly   538 LLTTAEAVVT 547
            |||:...::|
Yeast   552 LLTSCNTIIT 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60C	NP_608948.2	GroEL	28..548	CDD:239460	117/595 (20%)
TCM62	NP_009600.2	PTZ00114	124..492	CDD:185455	85/396 (21%)