Protein Alignment Hsp60C and CCT6

DIOPT Version :10

• Sequence 1: NP_608948.2
• Gene: Hsp60C / 33796
• FlyBaseID: FBgn0031728
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_010474.3
• Gene: CCT6 / 851768
• SGDID: S000002596
• Length: 546
• Species: Saccharomyces cerevisiae
• Alignment Length: 583
• Identity: 143/583 - (24%)
• Similarity: 224/583 - (38%)
• Gaps: 145/583 - (24%)

  Fly    47 LADAVAVTMGPKGRNVIIEQSWGSPKITKDGVTVAKSIALKDKFQNIGAKLVQDVANNTNEEAGD 111
            |...:...:||||...::....|:.|:||||    |.:..:.:.|:..|.|:...|...:|..||
Yeast    29 LQSVLETNLGPKGTLKMLVDGAGNIKLTKDG----KVLLTEMQIQSPTAVLIARAAAAQDEITGD 89

  Fly   112 GTTTATVLARAIAKEGFEKISRGASPVEIRRGVMLA-------IETVKDNLRRLSRPVNTPEEIC 169
            ||||...|...:.::....|..|..|..|..|..:|       ::..|.:...||   |..|.:.
Yeast    90 GTTTVVCLVGELLRQAHRFIQEGVHPRIITDGFEIARKESMKFLDEFKISKTNLS---NDREFLL 151

  Fly   170 QVATIS----ANGDKSVGNLISEAIKKVGRDGVITVKDGKTLCDELEV----------------- 213
            |||..|    .:.|      ::|.:..:..|.|::|.|.:  .|.|::
Yeast   152 QVARSSLLTKVDAD------LTEVLTPIVTDAVLSVYDAQ--ADNLDLHMVEIMQMQHLSPKDTT 208

  Fly   214 -IEGMKFDRGYISPYFINTSKGAKVEFQDALLLFCEKKIKSA---PSIVPALELANAQRKPLVII 274
             |:|:..|.|...|......|.|.|...:..|.:.:.::.|.   .|.....:||.::||  .:.
Yeast   209 FIKGLVLDHGGRHPDMPTRVKNAYVLILNVSLEYEKTEVNSGFFYSSADQRDKLAASERK--FVD 271

  Fly   275 AE-----DLEAEALST------LVVNRLKV---GLQVCAVKAPGFGDNRKENLMDMAVATGGIVF 325
            |:     ||:.|....      :::|:..:   .|.|.|          |.|::.:..|
Yeast   272 AKLKKIIDLKNEVCGMDPDKGFVIINQKGIDPMSLDVFA----------KHNILALRRA------ 320

  Fly   326 GDEANMVRLEDIKMSDFGRVGEVVVSKDDTMLLKGKGQKAEVEKRVEGL------------REAI 378
             ...||.||:                     |:.|    .|.:..||.|            :|.|
Yeast   321 -KRRNMERLQ---------------------LVTG----GEAQNSVEDLSPQILGFSGLVYQETI 359

  Fly   379 KESTSSYEKEKMQERLARLSSGVALLRVGGSSDVEVSEKKDRVIDALNATRAAV-EEGIVPGGGT 442
            .|...:|..|....:     |...|::  ||:...:::.||.|.|.|.|....: ::.|:||.|.
Yeast   360 GEEKFTYVTENTDPK-----SCTILIK--GSTHYALAQTKDAVRDGLRAVANVLKDKNIIPGAGA 417

  Fly   443 ---ALLRCIQKLNDLK-GANEDQNMGIEIIRRALRMPCLTIAKNAGVDGAMVVAKVE-----ILD 498
               ||.|.::..|..| ||......|||....||.:...|:.||:|.|...|:|.||     ..|
Yeast   418 FYIALSRYLRSANMNKLGAKGKTKTGIEAFAEALLVIPKTLVKNSGFDPLDVLAMVEDELDDAQD 482

  Fly   499 GD----YGYDALKGEYGNMIERGIIDPTKVVRTAISDAAGVAS-------LLTTAEAVVTELP 550
            .|    .|.|...|:..:....||.|..:|:|.||:.|.|:||       ||....:.:.|.|
Yeast   483 SDETRYVGVDLNIGDSCDPTIEGIWDSYRVLRNAITGATGIASNLLLCDELLRAGRSTLKETP 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60C	NP_608948.2	GroEL	28..548	CDD:239460	141/579 (24%)
CCT6	NP_010474.3	chap_CCT_zeta	2..542	CDD:274088	141/578 (24%)