Protein Alignment Hsp60C and MKKS

DIOPT Version :10

• Sequence 1: NP_608948.2
• Gene: Hsp60C / 33796
• FlyBaseID: FBgn0031728
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_061336.1
• Gene: MKKS / 8195
• HGNCID: 7108
• Length: 570
• Species: Homo sapiens
• Alignment Length: 198
• Identity: 47/198 - (23%)
• Similarity: 74/198 - (37%)
• Gaps: 65/198 - (32%)

  Fly   184 NLISEAIKKVGRDGVITVKDGK---TLCDELEVIEGMKFDRGYISPYFINTSKGAK--VEFQDAL 243
            ||| |.::::|......::..|   :||               || |..:.:.|.:  |:|....
Human   101 NLI-ENVQRLGLTPTTVIRLNKHLLSLC---------------IS-YLKSETCGCRIPVDFSSTQ 148

  Fly   244 LLFCEKKIKSAPSIVPALELANAQRKPLVIIAEDLEAEALSTLVVNRLKVGLQVCAVKAPG---F 305
            :|.|  .::|..:..||..|.   ||         |.|.:|.|:   |:..|......|.|   .
Human   149 ILLC--LVRSILTSKPACMLT---RK---------ETEHVSALI---LRAFLLTIPENAEGHIIL 196

  Fly   306 GDN-----RKENLMDMAVATGGIVFGDEANMVRLEDIK-----------------MSDFGRVGEV 348
            |.:     :.:.::|..|..|.::...|..::||..||                 .||.|. |.|
Human   197 GKSLIVPLKGQRVIDSTVLPGILIEMSEVQLMRLLPIKKSTALKVALFCTTLSGDTSDTGE-GTV 260

  Fly   349 VVS 351
            |||
Human   261 VVS 263

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60C	NP_608948.2	GroEL	28..548	CDD:239460	47/198 (24%)
MKKS	NP_061336.1	Cpn60_TCP1	29..569	CDD:395068	47/198 (24%)
		Substrate-binding apical domain	198..370		16/67 (24%)