Protein Alignment Hsp60C and Cct2

DIOPT Version :10

• Sequence 1: NP_608948.2
• Gene: Hsp60C / 33796
• FlyBaseID: FBgn0031728
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: XP_038934664.1
• Gene: Cct2 / 299809
• RGDID: 1359143
• Length: 561
• Species: Rattus norvegicus
• Alignment Length: 582
• Identity: 133/582 - (22%)
• Similarity: 219/582 - (37%)
• Gaps: 161/582 - (27%)

  Fly    43 GVDVLADAVAVTMGPKGRNVIIEQSW--GSPKITKDGVTVAKSIALKDKFQNIGAKLVQDVANNT 105
            |...:.|.|..|:||||.:.|:..|.  .|..:|.||.|:.|:|.:    .|..||::.|::...
  Rat    57 GAIAIGDLVKSTLGPKGMDKILLSSGRDASLMVTNDGATILKNIGV----DNPAAKVLVDMSRVQ 117

  Fly   106 NEEAGDGTTTATVLARAIAKEGFEKISRGASPVEIRRGVMLAIETVKDNLRRLSRPVNTP----- 165
            ::|.|||||:.||||..:.:|....|::...|..|..|...|.:..::.|  ||..|:..
  Rat   118 DDEVGDGTTSVTVLAAELLREAESLIAKKIHPQTIIAGWREATKAAREAL--LSSAVDHGSDEVK 180

  Fly   166 --EEICQVA--TISA-----NGD-------------KSVGNLISEAIKKVGRDGVITVKDGKTLC 208
              :::..:|  |:|:     :.|             |..|||  |||.       :..|.|.:|.
  Rat   181 FWQDLMNIAGTTLSSKLLTHHKDHFTKLAVEAVLRLKGSGNL--EAIH-------VIKKLGGSLA 236

  Fly   209 DELEVIEGMKFDRGYISPYFINTSKGAKVEFQDALLLFCE-----KKIKSAPSIVPALELANAQR 268
            |..       .|.|::....|..::..::|  :|.:|...     .|||...|.|.....|.
  Rat   237 DSY-------LDEGFLLDKKIGVNQPKRIE--NAKILIANTGMDTDKIKIFGSRVRVDSTAK--- 289

  Fly   269 KPLVIIAEDLEAEALSTLVVNRLKVGLQ--------------------VCAVKAPGFGDNRKENL 313
               |...|..|.|.:...|...||.|:.                    |.|::...|....:
  Rat   290 ---VAEIEHAEKEKMKEKVERILKHGINCFINRQLIYNYPEQLFGAAGVMAIEHADFAGVER--- 348

  Fly   314 MDMAVATGGIVFG--DEANMVRLEDIKMSDFGRVGE--------VVVSKDDTMLLKGKGQKA--E 366
              :|:.|||.:..  |...:|:|...|:.:...:||        |.:.:..|::|:|..|:.  |
  Rat   349 --LALVTGGEIASTFDHPELVKLGSCKLIEEVMIGEDKLIHFSGVALGEACTIVLRGATQQILDE 411

  Fly   367 VEKRVEG----LREAIKESTSSYEKEKMQERLARLSSGVALLRVGGSSDVEVSEKKDRVIDALNA 427
            .|:.:..    |.:.:|:..:.|.                    ||.|::            |.|
  Rat   412 AERSLHDALCVLAQTVKDPRTVYG--------------------GGCSEM------------LMA 444

  Fly   428 TRAAVEEGIVPGGGTALLRCIQKLNDLKGANEDQNMGIEIIRRALRMPCLTIAKNAGVDGAMVVA 492
            ....:.....||                    .:.:.:|...:||||....||.|||.|.|.:||
  Rat   445 HAVTMLASRTPG--------------------KEAVAMESFAKALRMLPTIIADNAGYDSADLVA 489

  Fly   493 KVEILDGD----YGYDALKGEYGNMIERGIIDPTKVVRTAISDAAGVASLLTTAEAVVTELP 550
            ::.....:    .|.|..:|..|:|...||.:..:|.|..:..||..|.::...:.::...|
  Rat   490 QLRAAHSEGRITAGLDMKEGSIGDMAVLGITESFQVKRQVLLSAAEAAEVILRVDNIIKAAP 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60C	NP_608948.2	GroEL	28..548	CDD:239460	132/578 (23%)
Cct2	XP_038934664.1	TCP1_beta	37..553	CDD:239452	133/582 (23%)