Protein Alignment Hsp60C and Cct3

DIOPT Version :10

• Sequence 1: NP_608948.2
• Gene: Hsp60C / 33796
• FlyBaseID: FBgn0031728
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_954522.1
• Gene: Cct3 / 295230
• RGDID: 735038
• Length: 545
• Species: Rattus norvegicus
• Alignment Length: 555
• Identity: 111/555 - (20%)
• Similarity: 219/555 - (39%)
• Gaps: 89/555 - (16%)

  Fly    33 GPEVRAMMLQGVDVLADAVAVTMGPKGRNVIIEQSWGSPKITKDGVTVAKSIALKDKFQNIGAKL 97
            |.:|::..:.....:||.:...:|||....::....|...:|.||..:.:.|    :.|:..||.
  Rat    19 GRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMTNDGNAILREI----QVQHPAAKS 79

  Fly    98 VQDVANNTNEEAGDGTTTATVLARAIAKEGFEKISRGASPVEIRRGVMLAIETVKDNLRRLSRPV 162
            :.:::...:||.|||||:..:||..:.......:.:...|..:.....:|::.:...|:::|.||
  Rat    80 MIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPTVVISAYRMALDDMVSTLKKISTPV 144

  Fly   163 NTPEEICQVATISANGDKSV--------GNLISEAIKKV-----GRDGVITVKDGKT------LC 208
            :.......:..|:::....|        .|:..:|:|.|     ||..:...|..:.      :.
  Rat   145 DVNNRDMMLNIINSSITTKVISRWSSLACNIALDAVKTVQFEENGRKEIDIKKYARVEKIPGGII 209

  Fly   209 DELEVIEGMKFDRGYISPYFINTSKGAKVEFQDALLLFCEKKIKSAPSIVPALELANAQRKPLVI 273
            ::..|:.|:..::....|......|..::...|:.|.:  ||.:|...|    |:...:....::
  Rat   210 EDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLDSSLEY--KKGESQTDI----EITREEDFTRIL 268

  Fly   274 IAEDLEAEALSTLVVNRLKVGLQVCAVKAPGFGDNRKENLMDMAVATGGIVFGDEANMVRLEDIK 338
               .:|.|.:..|..:.:::...| .:...|..|..:..||             .||:..:..::
  Rat   269 ---QMEEEYIQQLCEDIIQLKPDV-VITEKGISDLAQHYLM-------------RANVTAIRRVR 316

  Fly   339 MSDFGRV----GEVVVSKDDTMLLKGKGQKAEVEKRVEGLREAIKESTSSYE------KEKMQER 393
            .:|..|:    |..:||:.:.:.....|..|       ||.| ||:....|.      |:.
  Rat   317 KTDNNRIARACGARIVSRPEELREDDVGTGA-------GLLE-IKKIGDEYFTFITDCKDP---- 369

  Fly   394 LARLSSGVALLRVGGSSDVEVSEKKDRVIDALNATR-AAVEEGIVPGGGTALLRCIQKLNDLKGA 457
                .:...||| |.|.:: :||.:..:.||:...| ..::..:|||||.:.:.....|.:...|
  Rat   370 ----KACTILLR-GASKEI-LSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAHALTEKSKA 428

  Fly   458 NEDQNMGIE-----IIRRALRMPCLTIAKNAGVDGAMVVAKVEILDGDYGYD--ALKGEYGNMI- 514
                ..|:|     .:.:||.:...|:.:|.|.....::..:.........:  .:.||.|.::
  Rat   429 ----MTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGVNGETGTLVD 489

  Fly   515 --ERGIIDPTKVVRTAISDAAGVASLLTTAEAVVT 547
              |.||.:|..|.......|...|.||...:.:|:
  Rat   490 MKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVS 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60C	NP_608948.2	GroEL	28..548	CDD:239460	111/555 (20%)
Cct3	NP_954522.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..24		2/4 (50%)
		chap_CCT_gamma	6..529	CDD:274085	111/555 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	526..545