Protein Alignment Hsp60C and Cct5

DIOPT Version :10

• Sequence 1: NP_608948.2
• Gene: Hsp60C / 33796
• FlyBaseID: FBgn0031728
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_001004078.1
• Gene: Cct5 / 294864
• RGDID: 735161
• Length: 541
• Species: Rattus norvegicus
• Alignment Length: 543
• Identity: 126/543 - (23%)
• Similarity: 222/543 - (40%)
• Gaps: 122/543 - (22%)

  Fly    37 RAMMLQGVDVL------ADAVAVTM----GPKGRNVIIEQSWGSPKITKDGVTVAKSIALKDKFQ 91
            |...|.|::.|      |.|||.||    ||.|.:.::....|...:|.||.|:   :::.|...
  Rat    24 RKSRLMGLEALKSHIMAAKAVANTMRTSLGPNGLDKMMVDKDGDVTVTNDGATI---LSMMDVDH 85

  Fly    92 NIGAKLVQDVANNTNEEAGDGTTTATVLARAIAKEGFEKISRGASPVEIRRGVMLAIETVKDNLR 156
            .| |||:.:::.:.::|.|||||...|||.|:.:|..:.:.||..|:.|..|...|......:|.
  Rat    86 QI-AKLMVELSKSQDDEIGDGTTGVVVLAGALLEEAEQLLDRGIHPIRIADGYEQAARIAIQHLD 149

  Fly   157 RLSR----PVNTPEEICQVATISANGDKSVGNLISEAIKKVGRDGVITVKD-------------- 203
            ::|.    .:|.||.:.|.|..:. |.|.| |.....:.::..:.|:||.|
  Rat   150 KISDNVLVDINNPEPLIQTAKTTL-GSKVV-NSCHRQMAEIAVNAVLTVADMERRDVDFELIKVE 212

  Fly   204 GKT--LCDELEVIEGMKFDRGYISPYFINTSKGAKVEFQDALLL--FCEKKIKSAPSI-VPALEL 263
            ||.  ..::.::|:|:..|:.:..|........||:    |:|.  |...|.|:...: |.::|.
  Rat   213 GKVGGRLEDTKLIKGVIVDKDFSHPQMPKEVLNAKI----AILTCPFEPPKPKTKHKLDVTSVED 273

  Fly   264 ANAQRKPLVIIAEDLEAEALSTLVVNRLKVGLQVCAVKAPGFGDNRKENLMDMAVATGGIVFGDE 328
            ..|.:|        .|.|....::.       |:            ||...::|:...|  |.||
  Rat   274 YKALQK--------YEKEKFEEMIA-------QI------------KETGANLAICQWG--FDDE 309

  Fly   329 ANMVRLE------------DIKMSDFGRVGEVVVSKDDTMLLKGKGQKAEVEKRVEGLREAIKES 381
            ||.:.|:            :|::......|.:|            .:.:|:.....|....::|.
  Rat   310 ANHLLLQNGLPAVRWVGGPEIELIAIATGGRIV------------PRFSELTSEKLGFAGVVREI 362

  Fly   382 TSSYEKEKMQERLARLSSGVALLRVGGSSDVEVSEKKDRVIDALNATRAAVEEG-IVPGGGTALL 445
            :....|:||.......:|....:.:.|.:.:.:.|.|..:.|||...|..:.:. :|.|||.|.:
  Rat   363 SFGTTKDKMLVIEQCKNSRAVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVVYGGGAAEI 427

  Fly   446 RC---IQKLNDLKGANEDQNM-----GIEIIRRALRMPCLTIAKNAGVDGAMVVAKV---EILDG 499
            .|   :.:..|.....|...|     .:|:|..||       ::|:|::....:.:|   ::.:.
  Rat   428 SCALAVSQEADKCPTLEQYAMRAFADALEVIPMAL-------SENSGMNPIQTMTEVRARQVKES 485

  Fly   500 D--YGYDAL-KG----EYGNMIE 515
            :  .|.|.| ||    :|.::||
  Rat   486 NPALGIDCLHKGSNDMQYQHVIE 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60C	NP_608948.2	GroEL	28..548	CDD:239460	126/543 (23%)
Cct5	NP_001004078.1	TCP1_epsilon	10..535	CDD:239455	126/543 (23%)