Protein Alignment Hsp60C and Tcp1

DIOPT Version :10

• Sequence 1: NP_608948.2
• Gene: Hsp60C / 33796
• FlyBaseID: FBgn0031728
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_036802.1
• Gene: Tcp1 / 24818
• RGDID: 3832
• Length: 556
• Species: Rattus norvegicus
• Alignment Length: 588
• Identity: 129/588 - (21%)
• Similarity: 239/588 - (40%)
• Gaps: 139/588 - (23%)

  Fly    33 GPEVRAMMLQGVDVLADAVAVTMGPKGRNVIIEQSWGSPKITKDGVTVAKSIALKDKFQNIGAKL 97
            |..:|:..:.....:|:.|..::||.|.:.::....|...||.||.|:.|.:    :.::..||:
  Rat    14 GEAIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLL----EVEHPAAKV 74

  Fly    98 VQDVANNTNEEAGDGTTTATVLARAIAKEGFEKISRGASPVEIRRGVML----AIETVKDNL--- 155
            :.::|:..::|.|||||:..::|..:.|...|.:.:...|..:..|..|    |:..:.:||
  Rat    75 LCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVRYINENLIIN 139

  Fly   156 -RRLSRP--VNTPEEICQVATISANGDKSVGNLISEAIKKVGRDGV------------ITVKDGK 205
             ..|.|.  :|..:.......|..||| ...|::.:|:..|....:            |....|:
  Rat   140 TDELGRDCLINAAKTSMSSKIIGINGD-FFANMVVDAVLAVKYTDIRGQPRYPVNSVNILKAHGR 203

  Fly   206 TLCDELEVIEGMKFDRGYISPYFINTSKGAKVEFQDALLLFCEKKIKSAPSIVPALELANAQRKP 270
            :      .||.|     .|:.|.:|...|::     .:|    |:|.:|.  :..|:.
  Rat   204 S------QIESM-----LINGYALNCVVGSQ-----GML----KRIVNAK--IACLDF------- 239

  Fly   271 LVIIAEDLEAEALSTLVVNRLKVGLQVCAVKAPGFGDNRKENLMDMA-------VATGGIVFGDE 328
                          :|...::|:|:|| .:..|...|..::...|:.       :|||
  Rat   240 --------------SLQKTKMKLGVQV-VITDPEKLDQIRQRESDITKERIQKILATG------- 282

  Fly   329 ANMV----RLEDIKMSDFGRVGEV----VVSKDDTMLLKGKGQKAEVEKRVEGL--REAIKESTS 383
            ||::    .::|:.:..|...|.:    |:.:|...:.|..|  |.:...:..|  .|..:.:..
  Rat   283 ANVILTTGGIDDMCLKYFVEAGAMAVRRVLKRDLKRIAKASG--ASILSTLANLEGEETFEATML 345

  Fly   384 SYEKEKMQERL------------ARLSSGVALLRVGGSSDVEVSEKKDRVIDALNATRAAVE-EG 435
            ...:|.:|||:            ||.|:.: :||  |::|....|.:..:.|||...:..:| :.
  Rat   346 GQAEEVVQERICDDELILIKNTKARTSASI-ILR--GANDFMCDEMERSLHDALCVVKRVLESKS 407

  Fly   436 IVPGGG---TALLRCIQKLNDLKGANEDQNMGIEIIRRALRMPCLTIAKNAGVDGAMVVAKVEIL 497
            :|||||   .||...::......|:.|  .:.|....|:|.:...|:|.||..|...:|||:...
  Rat   408 VVPGGGAVEAALSIYLENYATSMGSRE--QLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAF 470

  Fly   498 DGD------------YGYDALKGEYGNMIERGIIDPTKVVRTAISDAAGVASLLTTAEAVVTELP 550
            ..:            .|.|.:.|:..:..:.|:.:|| :|:        |.||....||.:|.|.
  Rat   471 HNEAQVNPERKNLKWIGLDLVHGKPRDNKQAGVFEPT-IVK--------VKSLKFATEAAITILR 526

  Fly   551 LEE 553
            :::
  Rat   527 IDD 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60C	NP_608948.2	GroEL	28..548	CDD:239460	127/581 (22%)
Tcp1	NP_036802.1	TCP1_alpha	9..535	CDD:239451	129/588 (22%)