Protein Alignment Hsp60C and Tcp1

DIOPT Version :10

• Sequence 1: NP_608948.2
• Gene: Hsp60C / 33796
• FlyBaseID: FBgn0031728
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_038714.2
• Gene: Tcp1 / 21454
• MGIID: 98535
• Length: 556
• Species: Mus musculus
• Alignment Length: 579
• Identity: 125/579 - (21%)
• Similarity: 228/579 - (39%)
• Gaps: 121/579 - (20%)

  Fly    33 GPEVRAMMLQGVDVLADAVAVTMGPKGRNVIIEQSWGSPKITKDGVTVAKSIALKDKFQNIGAKL 97
            |..||:..:.....:|:.|..:.||.|.:.::....|...||.||.|:.|.:    :.::..||:
Mouse    14 GEAVRSQNVMAAASIANIVKSSFGPVGLDKMLVDDIGDVTITNDGATILKLL----EVEHPAAKV 74

  Fly    98 VQDVANNTNEEAGDGTTTATVLARAIAKEGFEKISRGASPVEIRRGVML----AIETVKDNL--- 155
            :.::|:..::|.|||||:..::|..:.|...|.:.:...|..:..|..|    |:..:.:||
Mouse    75 LCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVRYINENLIIN 139

  Fly   156 -RRLSRP--VNTPEEICQVATISANGDKSVGNLISEAIKKVGRDGVITVK------DGKTLCDEL 211
             ..|.|.  :|..:.......|..|||.....::         |.|:.||      ..:...:.:
Mouse   140 TDELGRDCLINAAKTSMSSKIIGINGDYFANMVV---------DAVLAVKYTDARGQPRYPVNSV 195

  Fly   212 EVIEG---MKFDRGYISPYFINTSKG----------AKVEFQDALLLFCEKKIKSAPSIVPALEL 263
            .:::.   .:.:...|:.|.:|...|          ||:...|..|...:.|:.....|....:|
Mouse   196 NILKAHGRSQIESMLINGYALNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKLGVQVVITDPEKL 260

  Fly   264 ANAQRKPLVIIAEDLEAEALSTLVVNRLKVGLQVCA---------VKAPGFGDNR--KENLMDMA 317
            ...:::     ..|:..|.:..::.....|.|....         |:|......|  |.:|..:|
Mouse   261 DQIRQR-----ESDITKERIQKILATGANVILTTGGIDDMYLKYFVEAGAMAVRRVLKRDLKHVA 320

  Fly   318 VATGGIVFGDEANMVRLEDIKMSDFGRVGEVVVSK--DDTMLLKGKGQKAEVEKRVEGLREAIKE 380
            .|:|..:....||:...|..:::..|:..|||..:  ||.::|                   ||.
Mouse   321 KASGASILSTLANLEGEETFEVTMLGQAEEVVQERICDDELIL-------------------IKN 366

  Fly   381 STSSYEKEKMQERLARLSSGVALLRVGGSSDVEVSEKKDRVIDALNATRAAVE-EGIVPGGG--- 441
            :.            ||.|:.: :||  |::|....|.:..:.|||...:..:| :.:|||||
Mouse   367 TK------------ARTSASI-ILR--GANDFMCDEMERSLHDALCVVKRVLELKSVVPGGGAVE 416

  Fly   442 TALLRCIQKLNDLKGANEDQNMGIEIIRRALRMPCLTIAKNAGVDGAMVVAKVEILDGD------ 500
            .||...::......|:.|  .:.|....|:|.:...|:|.||..|...:|||:.....:
Mouse   417 AALSIYLENYATSMGSRE--QLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPE 479

  Fly   501 ------YGYDALKGEYGNMIERGIIDPTKVVRTAISDAAGVASLLTTAEAVVTELPLEE 553
                  .|.|.:.|:..:..:.|:.:|| :|:        |.||....||.:|.|.:::
Mouse   480 RKNLKWIGLDLVHGKPRDNKQAGVFEPT-IVK--------VKSLKFATEAAITILRIDD 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60C	NP_608948.2	GroEL	28..548	CDD:239460	123/572 (22%)
Tcp1	NP_038714.2	TCP1_alpha	9..535	CDD:239451	125/579 (22%)