Protein Alignment Hsp60C and cct-2

DIOPT Version :10

• Sequence 1: NP_608948.2
• Gene: Hsp60C / 33796
• FlyBaseID: FBgn0031728
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_741031.1
• Gene: cct-2 / 174421
• WormBaseID: WBGene00000378
• Length: 529
• Species: Caenorhabditis elegans
• Alignment Length: 586
• Identity: 143/586 - (24%)
• Similarity: 245/586 - (41%)
• Gaps: 125/586 - (21%)

  Fly    24 RNYAKDVRFGPEVRAMMLQGVDVLADAVAVTMGPKGRNVII----EQSWGSPKITKDGVTVAKSI 84
            ::.|::.| |...|.....|...:.|.|..|:||||.:.|:    .:|.|..|:|.||.|:.|||
 Worm     8 KDNAQEER-GESARLSSFVGAIAIGDLVKSTLGPKGMDKILISGNPESAGGIKVTNDGATILKSI 71

  Fly    85 ALKDKFQNIGAKLVQDVANNTNEEAGDGTTTATVLARAIAKEGFEKISRGASPVEI----RRGVM 145
            .:    .|..||::.|::...:.|.|||||:.||||..:.||..:.:::...|..|    ||.:.
 Worm    72 GV----DNPAAKVLVDMSMTQDHEVGDGTTSVTVLAAELLKEAEKLVNQRIHPQTIISGYRRALG 132

  Fly   146 LAIETVK-------DNLR----RLSRPV-------NTPEEICQVATISANGDKSVGNLIS-EAIK 191
            :|.|::|       ||:|    :::|..       ...|...|:|..:....|..|||.: :.||
 Worm   133 IAQESLKKSSIESGDNIRDDLLKIARTTLGSKILSQHKEHFAQLAVDAVLRLKGSGNLDAIQIIK 197

  Fly   192 KVGRDGVITVKDGKTLCDE---LEVIEGM----KFDRGYI----SPYFINTSK----GAKVEFQD 241
            |:|  |.:    .::..||   ||.:.||    :.::..|    :|  ::|.|    |::|.. |
 Worm   198 KLG--GSM----NESYLDEGFLLEKLPGMFQPRRVEKAKILIANTP--MDTDKVKVFGSRVRV-D 253

  Fly   242 ALLLFCEKKIKSAPSIVPALELANAQRKPLVIIAEDLEAEALSTLVVN---RLKVGLQVCAVKAP 303
            .:....|         :.|.|....:.|...|:|.:........|:.|   :|....:|.|::..
 Worm   254 GVAKVAE---------LEAAEKLKMKEKVDKILAHNCNVFINRQLIYNYPEQLFADAKVMAIEHA 309

  Fly   304 GFGDNRKENLMDMAVATGGIVFGDEANMVRLEDIKMSDFGR---VGEVVVSKDDTMLLKGKGQKA 365
            .|     |.:..:|:..||.:      :...:..:.:.||.   :.|:::.:|  .||:..|.|
 Worm   310 DF-----EGIERLALVLGGEI------VSTFDSPQTAQFGSCDLIEEIMIGED--RLLRFSGVK- 360

  Fly   366 EVEKRVEGLREAIKESTSSYEKEKMQERLARLSSGVALLRVGGSSDVEVSEKKDRVIDALNATRA 430
                    |.||..                      .:||  |::...:.|.:..:.|||.....
 Worm   361 --------LGEACS----------------------VVLR--GATQQILDESERSLHDALCVLVT 393

  Fly   431 AVEEG-IVPGGGTA--LLRCIQKLNDLKGANEDQNMGIEIIRRALRMPCLTIAKNAGVDGAMVVA 492
            .|:|. .|.|.|.:  |:.....:...|.|.::. :.:|...|||......|..|||:|.|.:|.
 Worm   394 HVKESKTVAGAGASEILMSSAIAVEAQKVAGKEA-LAVEAFGRALAQLPTIICDNAGLDSAELVT 457

  Fly   493 KV--EILDG--DYGYDALKGEYGNMIERGIIDPTKVVRTAISDAAGVASLLTTAEAVVTELPLEE 553
            ::  |..:|  :.|.|..|||..::.:.|:|:...|....:|.||.....:...:.::...|...
 Worm   458 RLRAEHANGRHNMGIDIEKGEVADVTKLGVIESYNVKLCMVSSAAEATEQILRVDDIIKAAPRAR 522

  Fly   554 A 554
            |
 Worm   523 A 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60C	NP_608948.2	GroEL	28..548	CDD:239460	140/574 (24%)
cct-2	NP_741031.1	TCP1_beta	6..520	CDD:239452	141/581 (24%)