Protein Alignment Hsp60C and cct-4

DIOPT Version :10

• Sequence 1: NP_608948.2
• Gene: Hsp60C / 33796
• FlyBaseID: FBgn0031728
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_495750.1
• Gene: cct-4 / 174330
• WormBaseID: WBGene00000379
• Length: 540
• Species: Caenorhabditis elegans
• Alignment Length: 584
• Identity: 138/584 - (23%)
• Similarity: 239/584 - (40%)
• Gaps: 128/584 - (21%)

  Fly    24 RNYAKDVRFGPEVRAMMLQGVDVLADAVAVTMGPKGRNVIIEQSWGSPKITKDGVTVAKSIALKD 88
            ||: ||......||...:.....:||||..::||:|.:.:|:...|...||.||.|:...:::
 Worm    21 RNF-KDKDKPESVRNSNIVAAKAVADAVRTSLGPRGMDKMIQSGNGDVTITNDGATILNQMSV-- 82

  Fly    89 KFQNIGAKLVQDVANNTNEEAGDGTTTATVLARAIAKEGFEKISRGASPVEIRRGVMLAIETVKD 153
              .:..||::.:::...:.||||||||..|:|.|:.......:|:|..|..|......|....:.
 Worm    83 --IHPTAKMLVELSKAQDIEAGDGTTTVVVMAGALLDAAQNLLSKGIHPTTISESFQSAAAEAEK 145

  Fly   154 NLRRLSRPVNTPEE--ICQVATISANGDKSVGN-------LISEAIKKV---GRDGVITVKDGKT 206
            .|..:|.||:...:  :.::||.|.| .|.|..       :...|:||:   ..|..:.:|..|.
 Worm   146 ILDEMSSPVDLSNDALLNKMATTSLN-SKVVSQHSWLLAPMAVNAVKKIINSENDSNVNLKMIKI 209

  Fly   207 L------CDELEVIEGMKFDR---GYISPYFINTSKGAKVEFQDALLLFCEKKIKSAPSIVPALE 262
            :      .:|.|:|||...|:   |..:|..|..:|...::||            .:|   |..:
 Worm   210 IKKMGDTVEESELIEGALIDQKTMGRGAPTRIEKAKIGLIQFQ------------ISP---PKTD 259

  Fly   263 LAN---------------AQRKPLVIIAEDLEAEALSTLVVNRLKVGLQVCAVKAPGFGDNRKEN 312
            :.|               .:|:.|:.|.:.::|...:.|::                    :|..
 Worm   260 MENQVIITDYAQMDRALKEERQYLLEICKQIKAAGCNVLLI--------------------QKSI 304

  Fly   313 LMDMAVATGGIVFGDEANMVRLEDIKMSD---FGRV-GEVVVSKDDTMLLKGKGQKAEVEK---- 369
            |.| ||....:.|..:..::.::||:..|   :.|: |...|:..|.......|....||:
 Worm   305 LRD-AVNELALHFLAKMKIMCIKDIEREDIEFYSRILGCRPVASVDHFNADALGYADLVEEIPTG 368

  Fly   370 ------RVEGLREAIKESTSSYEKEKMQERLARLSSGVALLRVGGSSDVEVSEKKDRVI-DALNA 427
                  :|.|::..                    ...|::|..|  |:..|.|:.||.| |||..
 Worm   369 GDGKVIKVTGVQNP--------------------GHAVSILLRG--SNKLVLEEADRSIHDALCV 411

  Fly   428 TRAAV-EEGIVPGGGTALLRCIQKLNDLKGANEDQNMGIEIIRR----ALRMPCLTIAKNAGVDG 487
            .|..| ::.::||||...:....||.:|.   :.|:...:...|    ||.:...|:|:|||:..
 Worm   412 IRCLVKKKALLPGGGAPEMEIAVKLRNLA---QTQHGATQYCWRAFADALELIPYTLAENAGLSP 473

  Fly   488 AMVVAKVEIL----DGDYGYDALKGEYGNMIERGIIDPTKVVRTAISDAAG-VASLLTTAEAVV 546
            ...|.::...    :..||.:..||...:|:|..::.|..|..:||..|:. |.|:|...:.|:
 Worm   474 IHTVTELRNNHANGNSSYGVNVRKGYVTDMVEEDVVQPLLVTASAIKQASECVRSILKIDDIVM 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60C	NP_608948.2	GroEL	28..548	CDD:239460	136/580 (23%)
cct-4	NP_495750.1	chap_CCT_delta	23..539	CDD:274083	136/582 (23%)