Protein Alignment Hsp60C and cct-1

DIOPT Version :10

• Sequence 1: NP_608948.2
• Gene: Hsp60C / 33796
• FlyBaseID: FBgn0031728
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_495722.1
• Gene: cct-1 / 174318
• WormBaseID: WBGene00000377
• Length: 549
• Species: Caenorhabditis elegans
• Alignment Length: 588
• Identity: 132/588 - (22%)
• Similarity: 228/588 - (38%)
• Gaps: 140/588 - (23%)

  Fly    33 GPEVRAMMLQGVDVLADAVAVTMGPKGRNVIIEQSWGSPKITKDGVTVAKSIALKDKFQNIGAKL 97
            |..:|:..:.....:|:.|..::||.|.:.::....|...:|.||.|:.|.:    :.::...|:
 Worm    18 GQGIRSQNVTAAVAIANIVKSSLGPVGLDKMLVDDVGDVIVTNDGATILKQL----EVEHPAGKV 78

  Fly    98 VQDVANNTNEEAGDGTTTATVLARAIAKEGFEKISRGASPVEIRRGVMLAI-ETVK--------- 152
            :.::|...:||.|||||:..::|..:.|...|.:.:...|..|..|..||. |.||
 Worm    79 LVELAQLQDEEVGDGTTSVVIVAAELLKRADELVKQKVHPTTIINGYRLACKEAVKYISENISFT 143

  Fly   153 -DNLRRLSRPVNTPEEICQVATISANGDKSVGNLISEAIK--KVGRDGVITV---------KDGK 205
             |::.|.| .||..:.......|..:.| ..|.|:.:|.:  :|..:|.:|.         ..||
 Worm   144 SDSIGRQS-VVNAAKTSMSSKIIGPDAD-FFGELVVDAAEAVRVENNGKVTYPINAVNVLKAHGK 206

  Fly   206 TLCDELEVIEGMKFDRGY---------ISPYFINTSKGAKVEFQDALLLFCEKKIKSAPSIV--- 258
            :..:.:.|       :||         ..|..:..:|.|.::|.     ..:.|:....|:|
 Worm   207 SARESVLV-------KGYALNCTVASQAMPLRVQNAKIACLDFS-----LMKAKMHLGISVVVED 259

  Fly   259 PALELANAQRKPLVIIAEDLEAEALSTLVVNRLKVGLQVCAVKAPGFGDNRKENLMDMAVATGGI 323
            || :|...:|:..     |:....:..:    ||.|..|                   .:.||||
 Worm   260 PA-KLEAIRREEF-----DITKRRIDKI----LKAGANV-------------------VLTTGGI 295

  Fly   324 VFGDEANMVRLEDIKMSDFGRVGEVVVSK----DDTMLLKGKGQKAEVE-KRVEGLREAIKESTS 383
                       :|:.:..|...|.:.|.:    |...:.|..|....|. ..:|| .||...|..
 Worm   296 -----------DDLCLKQFVESGAMAVRRCKKSDLKRIAKATGATLTVSLATLEG-DEAFDASLL 348

  Fly   384 SYEKEKMQERL------------ARLSSGVALLRVGGSSDVEVSEKKDRVIDALNATRAAVE-EG 435
            .:..|.:|||:            :|.:|.: :||  |::||.:.|.:..|.|:|...|..:| :.
 Worm   349 GHADEIVQERISDDELILIKGPKSRTASSI-ILR--GANDVMLDEMERSVHDSLCVVRRVLESKK 410

  Fly   436 IVPGGG---TALLRCIQKLNDLKGANEDQNMGIEIIRRALRMPCLTIAKNAGVDGAMVVAKVEIL 497
            :|.|||   |:|...::.......:.|  .:.:.....||.:....:|.||..|...:|.|:...
 Worm   411 LVAGGGAVETSLSLFLETYAQTLSSRE--QLAVAEFASALLIIPKVLASNAARDSTDLVTKLRAY 473

  Fly   498 DGD------------YGYDALKGEYGNMIERGIIDPTKVVRTAISDAAGVASLLTTAEAVVTELP 550
            ...            .|.|..:|...:..|.||::|      |:|.   |.||....||.:|.|.
 Worm   474 HSKAQLIPQLQHLKWAGLDLEEGTIRDNKEAGILEP------ALSK---VKSLKFATEAAITILR 529

  Fly   551 LEE 553
            :::
 Worm   530 IDD 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60C	NP_608948.2	GroEL	28..548	CDD:239460	130/581 (22%)
cct-1	NP_495722.1	TCP1_alpha	13..538	CDD:239451	132/588 (22%)