Protein Alignment Hsp60C and CCT1

DIOPT Version :10

• Sequence 1: NP_608948.2
• Gene: Hsp60C / 33796
• FlyBaseID: FBgn0031728
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: XP_313154.4
• Gene: CCT1 / 1274083
• VectorBaseID: AGAMI1_012504
• Length: 557
• Species: Anopheles gambiae
• Alignment Length: 602
• Identity: 133/602 - (22%)
• Similarity: 231/602 - (38%)
• Gaps: 127/602 - (21%)

  Fly    33 GPEVRAMMLQGVDVLADAVAVTMGPKGRNVIIEQSWGSPKITKDGVTVAKSIALKDKFQNIGAKL 97
            |..||...:.....:|:.|..::||.|.:.::....|...:|.||.|:.|.:    :.::..||:
Mosquito    17 GAPVRTQNVMAASSIANIVKSSLGPVGLDKMLVDDIGDVTVTNDGATILKLL----EVEHPAAKV 77

  Fly    98 VQDVANNTNEEAGDGTTTATVLARAIAKEGFEKISRGASPVEIRRGVMLAI-ETVKDNLRRLSRP 161
            :.::|...:||.|||||:..::|..:.|...|.:.:...|..|..|..||. |..|.....|:.|
Mosquito    78 LCELAQLQDEEVGDGTTSVVIIAAELLKNADELVKQKIHPTSIIAGYRLACKEACKYISEHLTAP 142

  Fly   162 VNT--PEEICQVA-------TISANGDKSVGNLI--SEAIKKVGRDG--------VITVK-DGKT 206
            |:.  .|.:..||       .|.|:.|.....::  ::|:|.:...|        |..:| .||:
Mosquito   143 VDDLGRETLINVAKTSMSSKIIGADADFFATMVVDAAQAVKILDPKGNPAYPIKAVNVLKAHGKS 207

  Fly   207 LCDELEVIEGMKFDRGYISPYFINTSKGAKVEFQDALLLFCEKKIKSAPSIVPALELANAQRKPL 271
            ..:.: :::|...:....|.........||:...|..|...:.|:.....|....:|...:.:.|
Mosquito   208 ARESI-LVQGYALNCTIASQQMPKKIVNAKIACLDFSLQKTKMKMGVQVLITDPEKLEGIRAREL 271

  Fly   272 VIIAEDLEAEALSTLVVNRLKVGLQVCA-----------VKAPGFGDNR--KENLMDMAVATGGI 323
            .|..|.:| :.|:|      .|.:.:|:           |:|......|  |.:|..:|.|||..
Mosquito   272 DITKEKIE-KILAT------GVNVVLCSGGIDDLCLKYFVEAGAMAVRRVKKADLKRIAKATGAA 329

  Fly   324 VFGDEANMVRLEDIKMSDFGRVGEVV---VSKDDTMLLKGKGQKAEVEKRVEGLREAIKESTSSY 385
            ......||...|....|..|...|||   :..|:.:|::|.
Mosquito   330 YLTSLTNMEGEESFDASYVGEAAEVVQEFICDDELILIRGP------------------------ 370

  Fly   386 EKEKMQERLARLSSGVALLRVGGSSDVEVSEKKDRVIDALNATRAAVE-EGIVPGGGTALLRCIQ 449
                    .||.::.: :||  |.:|....|.:..:.|||...:..:| :.:|.|||     |::
Mosquito   371 --------KARTAASI-ILR--GPNDFYCDEMERSIHDALCVAKRVLEGKKVVAGGG-----CVE 419

  Fly   450 KL------NDLKGANEDQNMGIEIIRRALRMPCLTIAKNAGVDGAMVVAKVEILDGD-------- 500
            ..      |.....:..:.:.|....::|.:...|:|.||..|...:|||:......
Mosquito   420 AALSIYLENFATSLSSREQLAIAEFAKSLLVIPKTLAVNAAKDATDLVAKLRAYHNSSQTVVDHA 484

  Fly   501 ----YGYDALKGEYGNMIERGIIDPTKVVRTAISDAAGVASLLTTAEAVVTELPLEEAAAA---- 557
                ||.|.::|...:..:.|:::|      |:|.   :.||....||.:|.|.:::....
Mosquito   485 QLKWYGLDLIEGVVKDNKKAGVLEP------AMSK---IKSLKFATEAAITILRIDDMITLNPEE 540

  Fly   558 ------GAAAGLGALGG 568
                  |.|...|.|.|
Mosquito   541 KGGKNYGDACAAGELDG 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60C	NP_608948.2	GroEL	28..548	CDD:239460	126/570 (22%)
CCT1	XP_313154.4	TCP1_alpha	12..538	CDD:239451	128/581 (22%)