Protein Alignment Hsp60C and CCT4

DIOPT Version :10

• Sequence 1: NP_608948.2
• Gene: Hsp60C / 33796
• FlyBaseID: FBgn0031728
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: XP_310191.2
• Gene: CCT4 / 1271406
• VectorBaseID: AGAMI1_004018
• Length: 533
• Species: Anopheles gambiae
• Alignment Length: 573
• Identity: 130/573 - (22%)
• Similarity: 241/573 - (42%)
• Gaps: 112/573 - (19%)

  Fly    28 KDVRFGPEVRAMMLQGVDVLADAVAVTMGPKGRNVIIEQSWGSPKITKDGVTVAKSIALKDKFQN 92
            ||.....::|...:.....::||:..::||:|.:.:|:.|.|...||.||.|:.|.:       |
Mosquito    18 KDKSKPADIRLSNINAAKAVSDAIRTSLGPRGMDKMIQASNGEVTITNDGATILKQM-------N 75

  Fly    93 I---GAKLVQDVANNTNEEAGDGTTTATVLARAIAKEGFEK-ISRGASPVEIRRGVMLAIETVKD 153
            :   .||::.:::...:.|||||||:..|:|.|:. |..|| :..|..|..|............:
Mosquito    76 VIHPAAKMLVELSRAQDVEAGDGTTSVVVVAGALL-EAVEKLLQMGIHPTAISEAFQRCSAKAVE 139

  Fly   154 NLRRLSRPV--NTPEEICQVATISANG------DKSVGNLISEAIKKV---GRDGVITVKDGKTL 207
            .|..:||||  |..|.:.:.|:.|.|.      ...:..:..:|:.||   ...|.:.:|:.|.:
Mosquito   140 ILTEMSRPVELNDRETLIKSASTSLNSKVVSQHSSMLAPIAVDAVLKVTESHEQGSVDLKNIKLI 204

  Fly   208 ------CDELEVIEGMKFDR---GYISPYFINTSKGAKVEFQDALLLFCEKKIKSAP------SI 257
                  .::.|:|:|:.|.:   |...|..:..:|       ..|:.||    .|||      |:
Mosquito   205 RSLGGTIEDTELIDGLVFTQRSSGINGPKRLEKAK-------IGLIQFC----ISAPKTDMDHSV 258

  Fly   258 V----PALE-LANAQRKPLVIIAEDLEAEALSTLVVNRLKVGLQVCAVKAPGFGDNRKENLMDMA 317
            :    .|:: :...:|..::.|.:.::....:.|:|                    :|..|.| |
Mosquito   259 IVSDYAAMDRVLKEERAYILNIVKQIKKSGCNVLLV--------------------QKSILRD-A 302

  Fly   318 VATGGIVFGDEANMVRLEDIKMSDFGRVGEV-----VVSKDDTMLLKGKGQKAEVEKRVEG-LRE 376
            |:.....|.|:..::.::||:..|...|.:.     :.|.|..:          .|..|.. |.|
Mosquito   303 VSDLAQHFLDKIKVMVVKDIEREDVEFVCKTLRCRPIASLDHFV----------AENLVNADLVE 357

  Fly   377 AIKESTSSYEKEKMQERLARLSSGVALLRVGGSSDVEVSEKKDRVI-DALNATRAAVEE-GIVPG 439
            .:...|:.:.|....:.:.:..|.|    |.||:.: |.|:.||.: |||...|..|:: .::.|
Mosquito   358 EVASGTTKFVKVTGIQNMGQTVSIV----VRGSNKL-VLEEADRSLHDALCVVRCLVKKRALIAG 417

  Fly   440 GGTALLRCIQKLNDLKGANEDQNMGIE-----IIRRALRMPCLTIAKNAGVDGAMVVAKVEIL-- 497
            ||...:....:|:    |......|::     ....||.:...|:|:|||::....|.::...
Mosquito   418 GGAPEIEMALQLS----AYAQTLQGVDAYCFRAFANALEVIPSTLAENAGLNPIATVTELRNRHA 478

  Fly   498 --DGDYGYDALKGEYGNMIERGIIDPTKVVRTAISDAA-GVASLLTTAEAVVT 547
              :.:.|.:..||...:::...::.|..|..::|:.|: .|.|:|...:.|.|
Mosquito   479 QGEKNAGINVRKGAITDILAENVVQPLLVSTSSITFASETVRSILKIDDIVNT 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60C	NP_608948.2	GroEL	28..548	CDD:239460	130/573 (23%)
CCT4	XP_310191.2	TCP1_delta	18..531	CDD:239454	129/571 (23%)