Protein Alignment Hsp60C and Cct5

DIOPT Version :10

• Sequence 1: NP_608948.2
• Gene: Hsp60C / 33796
• FlyBaseID: FBgn0031728
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_031663.1
• Gene: Cct5 / 12465
• MGIID: 107185
• Length: 541
• Species: Mus musculus
• Alignment Length: 546
• Identity: 126/546 - (23%)
• Similarity: 219/546 - (40%)
• Gaps: 128/546 - (23%)

  Fly    37 RAMMLQGVDVL------ADAVAVTM----GPKGRNVIIEQSWGSPKITKDGVTVAKSIALKDKFQ 91
            |...|.|::.|      |.|||.||    ||.|.:.::....|...||.||.|:   :::.|...
Mouse    24 RKSRLMGLEALKSHIMAAKAVANTMRTSLGPNGLDKMMVDKDGDVTITNDGATI---LSMMDVDH 85

  Fly    92 NIGAKLVQDVANNTNEEAGDGTTTATVLARAIAKEGFEKISRGASPVEIRRGVMLAIETVKDNLR 156
            .| |||:.:::.:.::|.|||||...|||.|:.:|..:.:.||..|:.|..|...|......:|.
Mouse    86 QI-AKLMVELSKSQDDEIGDGTTGVVVLAGALLEEAEQLLDRGIHPIRIADGYEQAARIAIQHLD 149

  Fly   157 RLSRPV----NTPEEICQVATISANGDKSVGNLISEAIKKVGRDGVITVKD-------------- 203
            ::|..|    |.||.:.|.|..:. |.|.: |.....:.::..:.|:||.|
Mouse   150 KISDKVLVDINNPEPLIQTAKTTL-GSKVI-NSCHRQMAEIAVNAVLTVADMERRDVDFELIKVE 212

  Fly   204 GKT--LCDELEVIEGMKFDRGYISPYFINTSKGAKVEFQDALLLFCEKKIKSAPSIVPALELANA 266
            ||.  ..::.::|:|:..|:.:..|........||:     .:|.|       |...|.   ...
Mouse   213 GKVGGRLEDTKLIKGVIVDKDFSHPQMPKKVVDAKI-----AILTC-------PFEPPK---PKT 262

  Fly   267 QRKPLVIIAEDLEA------EALSTLVVNRLKVGLQVCAVKAPGFGDNRKENLMDMAVATGGIVF 325
            :.|..|:..||.:|      |....::       .|:            ||...::|:...|  |
Mouse   263 KHKLDVMSVEDYKALQKYEKEKFEEMI-------KQI------------KETGANLAICQWG--F 306

  Fly   326 GDEANMVRLE------------DIKMSDFGRVGEVVVSKDDTMLLKGKGQKAEVEKRVEGLREAI 378
            .||||.:.|:            :|::......|.:|            .:.:|:.....|....:
Mouse   307 DDEANHLLLQNGLPAVRWVGGPEIELIAIATGGRIV------------PRFSELTSEKLGFAGVV 359

  Fly   379 KESTSSYEKEKMQERLARLSSGVALLRVGGSSDVEVSEKKDRVIDALNATRAAVEEG-IVPGGGT 442
            :|.:....|:||.......:|....:.:.|.:.:.:.|.|..:.|||...|..:.:. :|.|||.
Mouse   360 QEISFGTTKDKMLVIEKCKNSRAVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVVYGGGA 424

  Fly   443 ALLRC---IQKLNDLKGANEDQNM-----GIEIIRRALRMPCLTIAKNAGVDGAMVVAKV---EI 496
            |.:.|   :.:..|.....|...|     .:|:|..||       ::|:|::....:.:|   ::
Mouse   425 AEISCALAVSQEADKCPTLEQYAMRAFADALEVIPMAL-------SENSGMNPIQTMTEVRARQV 482

  Fly   497 LDGD--YGYDAL-KG----EYGNMIE 515
            .:.:  .|.|.| ||    :|.::||
Mouse   483 KESNPALGIDCLHKGSNDMQYQHVIE 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60C	NP_608948.2	GroEL	28..548	CDD:239460	126/546 (23%)
Cct5	NP_031663.1	TCP1_epsilon	10..535	CDD:239455	126/546 (23%)