Protein Alignment Hsp60C and Cct3

DIOPT Version :10

• Sequence 1: NP_608948.2
• Gene: Hsp60C / 33796
• FlyBaseID: FBgn0031728
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_033966.1
• Gene: Cct3 / 12462
• MGIID: 104708
• Length: 545
• Species: Mus musculus
• Alignment Length: 558
• Identity: 113/558 - (20%)
• Similarity: 223/558 - (39%)
• Gaps: 95/558 - (17%)

  Fly    33 GPEVRAMMLQGVDVLADAVAVTMGPKGRNVIIEQSWGSPKITKDGVTVAKSIALKDKFQNIGAKL 97
            |.:|::..:.....:||.:...:|||....::....|...:|.||..:.:.|    :.|:..||.
Mouse    19 GRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMTNDGNAILREI----QVQHPAAKS 79

  Fly    98 VQDVANNTNEEAGDGTTTATVLARAIAKEGFEKISRGASPVEIRRGVMLAIETVKDNLRRLSRPV 162
            :.:::...:||.|||||:..:||..:.......:.:...|..:.....:|::.:...|:::|.||
Mouse    80 MIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPTVVISAYRMALDDMISTLKKISTPV 144

  Fly   163 NTPEEICQVATISANGDKSV--------GNLISEAIKKV-----GRDGVITVKDGKT------LC 208
            :.......::.|:::....|        .|:..:|:|.|     ||..:...|..:.      :.
Mouse   145 DVNNREMMLSIINSSITTKVISRWSSLACNIALDAVKTVQFEENGRKEIDIKKYARVEKIPGGII 209

  Fly   209 DELEVIEGMKFDRGYISPYFINTSKGAKVEFQDALLLFCEKKIKSAPSIVPALELANAQRKPLVI 273
            ::..|:.|:..::....|......|..::...|:.|.:  ||.:|...|    |:...:....::
Mouse   210 EDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLDSSLEY--KKGESQTDI----EITREEDFTRIL 268

  Fly   274 IAEDLEAEALSTLVVNRLKVGLQVCAVKAPGFGDNRKENLMDMAVATGGIVFGDEANMVRLEDIK 338
               .:|.|.:..|..:.:::...| .:...|..|..:..||             .||:..:..::
Mouse   269 ---QMEEEYIHQLCEDIIQLKPDV-VITEKGISDLAQHYLM-------------RANVTAIRRVR 316

  Fly   339 MSDFGRV----GEVVVSKDDTMLLKGKGQKAEVEKRVEGLREAIKESTSSYE------KEKMQER 393
            .:|..|:    |..:||:.:.:.....|..|       ||.| ||:....|.      |:.
Mouse   317 KTDNNRIARACGARIVSRPEELREDDVGTGA-------GLLE-IKKIGDEYFTFITDCKDP---- 369

  Fly   394 LARLSSGVALLRVGGSSDVEVSEKKDRVIDALNATR-AAVEEGIVPGGGTALLRCIQKLNDLKGA 457
                .:...||| |.|.:: :||.:..:.||:...| ..::..:|||||.:.:.....|.:...|
Mouse   370 ----KACTILLR-GASKEI-LSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAHALTEKSKA 428

  Fly   458 NEDQNMGIE-----IIRRALRMPCLTIAKNAGVDGAMVVAKVEILDGDYGYDA-----LKGEYGN 512
                ..|:|     .:.:||.:...|:.:|.   ||..:..:..|...:..::     :.||.|.
Mouse   429 ----MTGVEQWPYRAVAQALEVIPRTLIQNC---GASTIRLLTSLRAKHTQESCETWGVNGETGT 486

  Fly   513 MI---ERGIIDPTKVVRTAISDAAGVASLLTTAEAVVT 547
            ::   |.||.:|..|.......|...|.||...:.:|:
Mouse   487 LVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVS 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60C	NP_608948.2	GroEL	28..548	CDD:239460	113/558 (20%)
Cct3	NP_033966.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..24		2/4 (50%)
		chap_CCT_gamma	6..529	CDD:274085	113/558 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	526..545