Protein Alignment Hsp60C and CCT7

DIOPT Version :10

• Sequence 1: NP_608948.2
• Gene: Hsp60C / 33796
• FlyBaseID: FBgn0031728
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_006420.1
• Gene: CCT7 / 10574
• HGNCID: 1622
• Length: 543
• Species: Homo sapiens
• Alignment Length: 569
• Identity: 126/569 - (22%)
• Similarity: 227/569 - (39%)
• Gaps: 99/569 - (17%)

  Fly    41 LQGVDVLADAVAVTMGPKGRNVIIEQSWGSPKITKDGVTVAKSIALKDKFQNIGAKLVQDVANNT 105
            :....|:|:||..|:||:|.:.:|....|...|:.||.|:.|.:.:    .:..||.:.|:|.:.
Human    26 ISACQVIAEAVRTTLGPRGMDKLIVDGRGKATISNDGATILKLLDV----VHPAAKTLVDIAKSQ 86

  Fly   106 NEEAGDGTTTATVLARAIAKEGFEKISRGASPVEIRRGVMLAIETVKDNLRRLSRPVNTPEEI-- 168
            :.|.|||||:.|:||....|:....:..|..|..|.|....|.:...:.::.::..|...:::
Human    87 DAEVGDGTTSVTLLAAEFLKQVKPYVEEGLHPQIIIRAFRTATQLAVNKIKEIAVTVKKADKVEQ 151

  Fly   169 ------CQVATISANGDKSVGNLISEA---IKKVGRDGVITVKD-------------GKTLCDEL 211
                  |.:..:|:       .|||:.   ..|:..|.|:.:.|             |..| ::.
Human   152 RKLLEKCAMTALSS-------KLISQQKAFFAKMVVDAVMMLDDLLQLKMIGIKKVQGGAL-EDS 208

  Fly   212 EVIEGMKFDRGYISPYFINTSKGAKVEFQDALLLFCEKKIKSAPSIVPALELANAQRKPLVIIAE 276
            :::.|:.|.:.:....|....|  |.......||..|.::|:        |..||:.:  |...|
Human   209 QLVAGVAFKKTFSYAGFEMQPK--KYHNPKIALLNVELELKA--------EKDNAEIR--VHTVE 261

  Fly   277 DLEA--EALSTLVVNRLK----VGLQVCAVKAPGFGDNRKENLMDMAVATGGIVFGDE----ANM 331
            |.:|  :|...::.::|:    .|.:|...|.| .||          |||.  .|.|.    |..
Human   262 DYQAIVDAEWNILYDKLEKIHHSGAKVVLSKLP-IGD----------VATQ--YFADRDMFCAGR 313

  Fly   332 VRLEDIKMSDFGRVGEVVVSKDDTMLLKGKGQKAEVEKRVEGLREAIKESTSSYEKEKMQERLAR 396
            |..||:|.:.....|.:..|.:            .:...|.|..:..:|:....|:........:
Human   314 VPEEDLKRTMMACGGSIQTSVN------------ALSADVLGRCQVFEETQIGGERYNFFTGCPK 366

  Fly   397 LSSGVALLRVGGSSDVEVSEKKDRVIDALNATRAAVE-EGIVPGGGTALLRCIQKLND----LKG 456
            ..:...:||.|....:|.:|:.  :.||:...|.|:: :.:|.|||...:...:.|.|    :.|
Human   367 AKTCTFILRGGAEQFMEETERS--LHDAIMIVRRAIKNDSVVAGGGAIEMELSKYLRDYSRTIPG 429

  Fly   457 ANEDQNMGIEIIRRALRMPCLTIAKNAGVDGAMVVAKVEILDGD----YGYDALKGEYGNMIERG 517
               .|.:.|....:||.:....:..|||.|...::.|:......    ||.|....:..:..|..
Human   430 ---KQQLLIGAYAKALEIIPRQLCDNAGFDATNILNKLRARHAQGGTWYGVDINNEDIADNFEAF 491

  Fly   518 IIDPTKVVRTAISDAAGVASLLTTAEAVV--TELPLEEAAAAGAAAGLG 564
            :.:|..|...|::.|:..|.|:.:.:..:  ....::...|||...|.|
Human   492 VWEPAMVRINALTAASEAACLIVSVDETIKNPRSTVDAPTAAGRGRGRG 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60C	NP_608948.2	GroEL	28..548	CDD:239460	121/551 (22%)
CCT7	NP_006420.1	TCP1_eta	5..525	CDD:239456	121/552 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	524..543		5/17 (29%)