Protein Alignment: GluRIIB and grik1b

• Sequence 1: NP_523485.3
• Gene: GluRIIB
• FlyBaseID: FBgn0020429
• Length: 913
• Species: Drosophila melanogaster
• Sequence 2: XP_690040.5
• Gene: grik1b
• ZFINID: ZDB-GENE-070821-1
• Length: 906
• Species: Danio rerio
• Alignment Length: 911
• Identity: 267/912 (29%)
• Similarity: 450/912 (49%)
• Gaps: 121/912 (13%)

  Fly     3 GLQFLVLLALA-IASGANEDTLVIKIGAIFFDTEMKLAD----AFSAALEEVN-----AINPALK 57
            |:.|::|..:| :...|.:   |::||.||...|.:...    ||..|:..:|     ..|..|.
Zfish    44 GVSFILLCLMAEVGLSAQQ---VLRIGGIFETLENEPISVEELAFKFAVTNINRNRTLMPNTTLT 105

  Fly    58 LDAIKRYVTVDDSIVLQDISCDLIGSGVAAIFGPSSKTNSDIVEVLCNMTGIPHLQFDW-HPQQS 121
            .| |:| :.:.||......:||.:..||||:||||..::...|:.:||...:||:|..| ||...
Zfish   106 YD-IQR-INLFDSFEASRRACDQLALGVAAVFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVD 168

  Fly   122 NRERMNHQLTVNVAPMELFLSAAFSDILASKTFDWKSFTIAYERSSHLIRLQHILAWKQLHKAGI 186
            |::    ...:|:.|....:|.|..||:  :.:.||:.|:.||.::.|||||.::.....:...|
Zfish   169 NKD----SFYINLYPDYASISRAVLDIV--QFYKWKAVTVVYEDATGLIRLQELIKAPSRYSIKI 227

  Fly   187 KMQEFERGD-DYRILWKRINNAREKFVLLDCPSDILVDVINASIGYNMTGSFNHLFLTNLDTHLS 250
            |:::...|. |.|.|.|.:...:|..|:.||......||:...:...|...:.|.|.|.||.:..
Zfish   228 KIRQLPTGSKDARPLLKEMKKGKEFCVIFDCSYQTAADVLKQLLSMGMMTEYYHFFFTTLDLYSL 292

  Fly   251 GIDGF-YSRDFTVAVAAVRI------------------RTYVPPPVHDEIDVFDNSVDTRFSSLG 296
            .::.| ||   .|.:...|:                  |...||  ..|..:.|..:.|.
Zfish   293 DLEPFRYS---GVNMTGFRLLNIDNPQVASVVEKWSMERLQAPP--KPETGLQDGMMTTE----- 347

  Fly   297 SQLVYDSIVLFYNALLEISQRPGFYIPNFSCGRGF-WQPGPRLVEQMKQ-----ITPKMVKPPFK 355
            :.|:||::.:...|....||   ..:.:..|.|.. |:.|.|.:...|:     :|.:::
Zfish   348 AALMYDAVYMVAAASQRASQ---ITVSSLQCHRHKPWRFGSRFISMFKEAQWNGLTGQII----- 404

  Fly   356 TQRLQIN-ADGQREDFNLEV----------------YNPIIDRVTHIWNKEFQLVDFEKLRENST 403
                 || .||.|:||:|::                :|.:..:: .:||....|        |.|
Zfish   405 -----INKTDGLRKDFDLDIISLKEDGLEKPLESGRFNKVWKKI-GVWNSNTGL--------NLT 455

  Fly   404 QALKQKRLQNKEDFSQKPIRYTVATRVGKPYFSWREEPEGVHYEGNERFEGYAVDLIYMLAQECK 468
            .:.|.|.....:..:.:.:  .|.|.:..||..:::..:.::  ||:|||||.:||:..|:....
Zfish   456 DSNKDKNTNVTDSMANRTL--IVTTILENPYVMYKKSDKPLY--GNDRFEGYCLDLLKELSNILG 516

  Fly   469 FDFNFEPVRDNKYGSYDANTDEWDGIIRQLIDNNAQIGICDLTITQARRSVVDFTVPFMQLGISI 533
            |.:..:.|.|.|||:.: :..||:|::|:|||:.|.:.:..||||..|..|:||:.|||.|||||
Zfish   517 FSYEVKLVTDGKYGAQN-DKGEWNGMVRELIDHVADLAVAPLTITYVREKVIDFSKPFMTLGISI 580

  Fly   534 LSYKEPPPKADIYAFLNPYNAEVWLFVMIAMMITAFALIFTGRIDQYEWDQPVE-NVNREMERQN 597
            |.:|.......:::||||.:.::|::|::|.:..:..|....|...|||..|.. |.:.::...|
Zfish   581 LYHKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCNPDSDVVENN 645

  Fly   598 IWHLSNALWLVLGSMLNQGCDLLPRGLPMRLLTAFWWIFALLISQTYIAKLAAFITSSKIAGDIG 662
             :.|.|::|..:|:::.||.:|:|:.|..|::...||.|.|:|..:|.|.||||:|..::...|.
Zfish   646 -FTLINSVWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMDSPID 709

  Fly   663 SLHDLVDQNKVQFGTIRGGATSVYFSESNDTDNRMAWNKMLSFKPDAFTKNNEEGVDRVKLSKGT 727
            |..||..|.|:::|.:|.|:|..:|.:|..:.....|..|.|.|..|..|||.||:.||..:  .
Zfish   710 SADDLAKQTKIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRKNTALVKNNREGIQRVLTT--D 772

  Fly   728 YAFLMETTNLQYYVQRNCELTQIGESFGEKHYGIAVPLNADFRSNLSVGILRLSERGELFKLRNK 792
            ||.|||:|:::|..||||.|||||.....|.||:..|:.:.:|..:::.||:|.|.|:|..::.|
Zfish   773 YALLMESTSIEYISQRNCNLTQIGGLIDSKGYGVGTPIGSPYRDKVTIAILQLQEEGKLHMMKEK 837

  Fly   793 WFNSNESTCDSNVPTIDDGQ---FDMDSVGGLFVVLIVGVVVGLVIGVAEFLW------HVQRIS 848
            |:..|      ..|..|..:   ..::::||:|:||..|:|:.:.:.:.||::      .::.:|
Zfish   838 WWRGN------GCPEEDSKEASALGVENIGGIFIVLAAGLVLSVFVAIGEFIYKSRKNLDIEEVS 896

  Fly   849 V 849
            |
Zfish   897 V 897

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIB	NP_523485.3	PBP1_iGluR_Kainate	26..393	CDD:107377	107/420 (25%)
		ANF_receptor	41..378	CDD:279440	99/386 (26%)
		PBP2_iGluR_Kainate	422..795	CDD:270432	136/374 (36%)
		Lig_chan	555..822	CDD:278489	91/271 (34%)
grik1b	XP_690040.5	Periplasmic_Binding_Protein_Type_1	62..455	CDD:299141	109/436 (25%)
		ANF_receptor	80..423	CDD:279440	98/374 (26%)
		Periplasmic_Binding_Protein_Type_2	471..840	CDD:304360	136/377 (36%)
		Lig_chan	602..871	CDD:278489	95/278 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C114469753
eggNOG	1	0.900				E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010				D60688at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100			O	PTHR18966
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.940