Protein Alignment CG9121 and mlt-2

DIOPT Version :8

• Sequence 1: NP_608901.1
• Gene: CG9121 / 33732
• FlyBaseID: FBgn0031675
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: NP_492036.2
• Gene: mlt-2 / 172459
• WormBaseID: WBGene00007252
• Length: 668
• Species: Caenorhabditis elegans
• Alignment Length: 480
• Identity: 103/481 (21%)
• Similarity: 173/481 (36%)
• Gaps: 134/481 (28%)

  Fly   138 REHDPHL--YDADVATPLHYAAYWGHEECVRILLEHNAPINVLNNDGYAPLHLGA--GFAGVTEL 198
            |:...|:  .|.|..|.||.||..|:.:.|..||::.|.|:.:|:.|....|..|  |...|.:.
 Worm    36 RDKKVHIDSVDDDQVTALHIAAAMGNNKLVVRLLDYGANIHAVNHLGMTAYHYAAREGKLAVLDT 100

  Fly   199 LIKHGALVNAKTLSDGKTALHMAIESKCAESARLLLQTNININDTDDDGE----TPLMAAIACSM 259
            |::.||..| :|.:.|.|||.:|.....|:..|.|::.:   |:|....:    |||:.|.....
 Worm   101 LMQRGASKN-QTTALGVTALTLACAGGHADVVRRLIRIS---NETPRSKQSLAPTPLIVATCSKS 161

  Fly   260 LDVAEELVKRGARINIQDKQ----NHTALQYAV---RGRHTQMAKLLLERGA----RRLASQHLL 313
            ..:...|.  ..|:|:.:..    |.|||..|:   .|  ..|.:.|::.||    :.|..:...
 Worm   162 PQICSYLA--DFRVNLDESMKNLGNLTALSMAIVCTPG--VYMVRTLIDLGASVNKKGLGDKTAE 222

  Fly   314 HLAVESNVKELVELLLQYGESLSVWN--------LKN---------------FTPIMLA-----I 350
            .||:..|.|:|:....:.....|..|        :||               .:|:|.|     |
 Worm   223 ELAIMLNRKDLIHFFNEKKSYRSRMNADSDVRKEIKNDHIIERELGAPAQNGVSPLMYATTVRSI 287

  Fly   351 HRGRHEMLEYLLNVAEEQRKLGLYSDVHDEGLVLFAVQQNFWVKEFSRILRV------------- 402
            :..:|.:|       .....:.:..::|...|            :.:.:|||
 Worm   288 NSAKHLVL-------HRDSDVNMRDNLHITSL------------QIASLLRVDDIIPLLLQRRAD 333

  Fly   403 --LLAKSPSARNDFY----DSCAPTIVCGLIYCHTPLSRAINLHRLEVAEFLIHEGCNLAQICRE 461
              ::.|..|...|.:    |...|..:.|.::||.|:....||:.                 ...
 Worm   334 VTVVNKYGSTAYDLFLLSCDFLEPGQLRGQLHCHRPIDSKSNLNS-----------------SSS 381

  Fly   462 HVVNELRSNCTPTRLAFARLLCNAGFQFPHKHRPL----PKDWPPARLEFEREMCLLGTQPRSLQ 522
            ::...|||.         .:|...|.|.......:    ||.|..|:.::         ||..|:
 Worm   382 NIYKALRSQ---------GILTKVGSQIGINSAKIELIEPKHWLAAKTKY---------QPAKLR 428

  Fly   523 SLARLEIRRSLLRCLQT--RPEVQE 545
            :..:......:|:..:.  |||..|
 Worm   429 NNYKFASVEDILKSCKVAKRPETNE 453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9121	NP_608901.1	ANK	151..300	CDD:238125	47/162 (29%)
		ANK repeat	151..179	CDD:293786	11/28 (39%)
		Ank_2	153..244	CDD:289560	31/93 (33%)
		ANK repeat	181..210	CDD:293786	9/31 (29%)
		ANK repeat	213..244	CDD:293786	10/31 (32%)
		Ank_2	218..304	CDD:289560	23/97 (24%)
		ANK	241..362	CDD:238125	35/164 (21%)
		ANK repeat	246..277	CDD:293786	7/35 (20%)
		ANK repeat	279..304	CDD:293786	9/32 (28%)
		Ank_4	311..362	CDD:290365	15/79 (19%)
		SOCS_box	518..574	CDD:284857	7/31 (23%)
mlt-2	NP_492036.2	Ank_2	22..111	CDD:289560	25/76 (33%)
		ANK	43..168	CDD:238125	38/129 (29%)
		ANK repeat	51..79	CDD:293786	11/28 (39%)
		ANK repeat	81..112	CDD:293786	10/32 (31%)
		Ank_2	119..214	CDD:289560	24/102 (24%)
		ANK repeat	144..179	CDD:293786	7/37 (19%)
		ANK repeat	181..214	CDD:293786	10/35 (29%)
		ANK	<269..347	CDD:238125	14/97 (14%)
		ANK repeat	273..305	CDD:293786	6/39 (15%)
		Ank_5	293..347	CDD:290568	9/73 (12%)
		ANK repeat	307..338	CDD:293786	5/43 (12%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
TreeFam	1	0.960
	1	0.960