Protein Alignment Col4a1 and Col9a2

DIOPT Version :10

• Sequence 1: NP_723044.1
• Gene: Col4a1 / 33727
• FlyBaseID: FBgn0000299
• Length: 1779
• Species: Drosophila melanogaster
• Sequence 2: NP_001102145.1
• Gene: Col9a2 / 362584
• RGDID: 1307029
• Length: 688
• Species: Rattus norvegicus
• Alignment Length: 1009
• Identity: 350/1009 - (34%)
• Similarity: 412/1009 - (40%)
• Gaps: 370/1009 - (36%)

  Fly   346 GPPGSTGQKGDRGEPGLNGLPGNPGQKGEPGRAGATGKPGLLGPPGPPGGGRGTPGPPGPKGPRG 410
            |||         |||||.|.||.||..|..|..|..|.||.:|||    |.:|.||.|||.||.
  Rat    26 GPP---------GEPGLPGPPGPPGVPGSDGIDGDKGPPGKVGPP----GSKGEPGKPGPDGPD- 76

  Fly   411 YVGAPGPQGLNGVDGLPGPQGYNGQKGGAGLPGRPGNEGPPGKKGEKGTAGLNGPKGSIGPIGHP 475
              |.||..||.|..|.|||.|..|.||..||||.||..||          |..||         |
  Rat    77 --GKPGIDGLMGAKGEPGPMGTPGIKGQPGLPGPPGLPGP----------GFAGP---------P 120

  Fly   476 GPPGPEGQKGDAGLPGYGIQGSKGDAGIPGYPGLKGSKGERGFKGNAGAPGDSKLGRPGTPGAAG 540
            |||||.|..|:.|.|     |.|||                                ||..|.:|
  Rat   121 GPPGPVGLPGEIGTP-----GPKGD--------------------------------PGPEGPSG 148

  Fly   541 APGQKGDAGRPGTPGQKGDMGIKGDVGGKC-SSCRAGPKGDKGTSGLPGIPGKDGARGPPGERGY 604
            .||..|..|||||     ..|::|.....| ::|.||.||.:|..|:.|.|||.|..|.||.:|.
  Rat   149 PPGPPGKPGRPGT-----IQGLEGSADFLCPTNCPAGVKGPQGLQGVKGHPGKRGILGDPGRQGK 208

  Fly   605 PGERGHDGINGQTGPPGEKGEDGRTGLPGATGEPGKPALCDLSLIEPLKGDKGYPGAPGAKGVQG 669
            ||.:|..|.:                                       |::|.||.||.:|::|
  Rat   209 PGPKGDVGAS---------------------------------------GEQGIPGPPGPQGIRG 234

  Fly   670 FKGAEGLPGIPGPKGEFGFKGEKGLSGAPGNDGTPGRAGRDGYPGIPGQSIKGEPGFHGRDGAKG 734
            :      ||:.|||||.|.:|.||:.|:.|..|.||..|..|.|
  Rat   235 Y------PGMAGPKGEMGPRGYKGMVGSIGAAGPPGEEGPRGPP--------------------- 272

  Fly   735 DKGSFGRSGEKGEPGSCALDEIKMPAKGNKGEPGQTGMPGPPGEDGSPGERGYTGLKGNTGPQGP 799
                 ||:||||:.||       ..|:|.:|..|..|..||||.||..|..|..|:||:.|..|.
  Rat   273 -----GRAGEKGDVGS-------QGARGPQGITGPKGTTGPPGIDGKDGTPGIPGMKGSAGQVGR 325

  Fly   800 PGVEGPRGLNGPRGEKGNQGAVGVPGNPGKDGLRGIPGRNGQPGPRGEPGISRPGPMGPPGLNGL 864
            |            |..|:||..||||.|   |.:|.||..|:||.:|.||||     |||   |.
  Rat   326 P------------GSPGHQGLAGVPGQP---GTKGGPGDKGEPGQQGFPGIS-----GPP---GK 367

  Fly   865 QGEKGDRGPTGPIGFPGADGSVGYPGDRGDAGLPGVSGRPGIVGEKGDVGPIGPAGVAGPPGVPG 929
            :||.|.||.|||                           .||:|||||.|..||.|..||
  Rat   368 EGEPGPRGETGP---------------------------QGIMGEKGDQGERGPVGQPGP----- 400

  Fly   930 IDGVRGRDGAKGEPGSPGL---VGMPGNKGDRGAPGNDGPKGFAGVTGAPGKRGPAGIPGVSGAK 991
                :||.|.|||.||||:   .|:||.|||:|:||..||            ||..|.|||:|..
  Rat   401 ----QGRQGPKGEQGSPGIPGPQGLPGIKGDKGSPGKTGP------------RGGVGDPGVAGLP 449

  Fly   992 GDKGATGLTGNDGPVGGRGPPGAPGLMGIKGDQGLAGAPGQQGLDGMPGEKGNQGFPGLDGPPGL 1056
            |:||..||:|.            |||   ||.||:.|.|      |.||..|:.|.||:.|.|||
  Rat   450 GEKGEKGLSGE------------PGL---KGQQGVRGEP------GYPGPSGDAGAPGVQGYPGL 493

  Fly  1057 PGDASEKGQKGEPGPSGLRGDTGPAGTPGWPGEKGLPGLAVHGRAGPPGEKGDQGRSGIDGRDGI 1121
                        |||.||.||.|..|.|                          ||.|:.||...
  Rat   494 ------------PGPRGLVGDRGVPGQP--------------------------GRQGVVGRAAS 520

  Fly  1122 NGEKGEQGLQGVWGQPGEKGSVGAPGIPGAPGMDGLPGAAGAPGAVGYPGDRGDKGEPGLSGLPG 1186
            :....:..|:.:..|..|..........||.||.||||..|.|   ||||.:|..|.||..|:||
  Rat   521 DQHIVDVVLKMIQEQLAEVAVSAKREALGATGMVGLPGPPGPP---GYPGKQGPNGHPGPRGIPG 582

  Fly  1187 LKGETGPVGLQGFTGAPGPKGERGIRGQPGLPATVPDIRGDKGSQGERGYTGEKGEQGERGLTGP 1251
            :.|..|.:      |..||||:|                            ||||:|||.|
  Rat   583 IVGAVGQI------GNTGPKGKR----------------------------GEKGDQGEMG---- 609

  Fly  1252 AGVAGAKGDRGLQGPPGASGLNGIPGAKGDIGPRGEIGYPGVTIKGEKGLPGRPGR--NGRQGLI 1314
                  :|..|:.|||      |||                       |||||||:  ||:.|..
  Rat   610 ------RGHPGMPGPP------GIP-----------------------GLPGRPGQAINGKDGDR 639

  Fly  1315 GAPGLIGERGLPGLAGEPGLVGLPGPIGPAGSKG 1348
            |:||..||.|.|   |.||.|||||...||...|
  Rat   640 GSPGAPGEAGRP---GRPGPVGLPGFCEPAACLG 670

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Col4a1	NP_723044.1	gly_rich_SclB	<107..>361	CDD:468478	5/14 (36%)
		gly_rich_SclB	<355..>642	CDD:468478	102/287 (36%)
		gly_rich_SclB	<543..820	CDD:468478	87/277 (31%)
		gly_rich_SclB	<727..>968	CDD:468478	94/243 (39%)
		gly_rich_SclB	<969..>1218	CDD:468478	80/248 (32%)
		gly_rich_SclB	<1186..>1420	CDD:468478	53/165 (32%)
		gly_rich_SclB	<1321..>1547	CDD:468478	15/28 (54%)
		C4	1555..1662	CDD:128421
		C4	1663..1777	CDD:128421
Col9a2	NP_001102145.1	gly_rich_SclB	<192..>437	CDD:468478	134/393 (34%)
		gly_rich_SclB	<346..>656	CDD:468478	171/503 (34%)