Protein Alignment Col4a1 and col-105

DIOPT Version :10

• Sequence 1: NP_723044.1
• Gene: Col4a1 / 33727
• FlyBaseID: FBgn0000299
• Length: 1779
• Species: Drosophila melanogaster
• Sequence 2: NP_500071.1
• Gene: col-105 / 186529
• WormBaseID: WBGene00000679
• Length: 290
• Species: Caenorhabditis elegans
• Alignment Length: 225
• Identity: 94/225 - (41%)
• Similarity: 109/225 - (48%)
• Gaps: 50/225 - (22%)

  Fly   245 GAKGPRGEHGLKGEKGASCYGPMKPGAPGIKGEKGEPASSFPVKPTHTVMGPRGDMGQKGEPGLV 309
            ||.||.||.|..|..|       |||.||:.|..|:|    |.:|...|..|      ...|...
 Worm    94 GAPGPTGEPGRPGRPG-------KPGVPGMPGNPGKP----PQQPCELVTPP------PCSPCPA 141

  Fly   310 GRKGEPGPEGDTGLDGQKGEKGLPGGPGDRGRQGNFGPPGSTGQKGDRGEPGLNGLPGNPGQKGE 374
            |..|:|||:      |..|:.|.||.||:||..|..||||.||..|:.|.||..|:.|.||...|
 Worm   142 GPPGKPGPQ------GAPGDIGQPGNPGERGMDGEPGPPGPTGPPGEPGLPGAQGITGQPGVNAE 200

  Fly   375 P--GRAGATGKPGLLGPPGPPGGGRGTPGPPGPKGPRGYVGAPGPQGLNGVDGLPGPQGYNGQKG 437
            |  .||||         ||||    |.|||||..|..|.:|..||      .|||||      ||
 Worm   201 PVAYRAGA---------PGPP----GEPGPPGAHGDPGDLGEEGP------PGLPGP------KG 240

  Fly   438 GAGLPGRPGNEGPPGKKGEKGTAGLNGPKG 467
            ..|..|.|||:||||.:|:.|.:|.:|.||
 Worm   241 PPGASGIPGNDGPPGARGQPGLSGDSGEKG 270

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Col4a1	NP_723044.1	gly_rich_SclB	<107..>361	CDD:468478	45/115 (39%)
		gly_rich_SclB	<355..>642	CDD:468478	51/115 (44%)
		gly_rich_SclB	<543..820	CDD:468478
		gly_rich_SclB	<727..>968	CDD:468478
		gly_rich_SclB	<969..>1218	CDD:468478
		gly_rich_SclB	<1186..>1420	CDD:468478
		gly_rich_SclB	<1321..>1547	CDD:468478
		C4	1555..1662	CDD:128421
		C4	1663..1777	CDD:128421
col-105	NP_500071.1	Col_cuticle_N	10..62	CDD:198156
		gly_rich_SclB	<93..>270	CDD:468478	92/223 (41%)