DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Scox and sco-1

DIOPT Version :9

Sequence 1:	NP_608884.1	Gene:	Scox / 33711	FlyBaseID:	FBgn0262467	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	NP_494755.1	Gene:	sco-1 / 173763	WormBaseID:	WBGene00015297	Length:	312	Species:	Caenorhabditis elegans

Alignment Length:	240	Identity:	111/240 - (46%)
Similarity:	155/240 - (64%)	Gaps:	18/240 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 RRWAQQPAIRHYAAPADSTKGKGPISWRSLAVIGALGAGG--VGFMLYVKSEKDEARMKERQRQL 75
            |:.|:|.|.:..:.          .:|::  |:|....||  :..:.|:|..:.:.|.|.|::..
Worm    80 RKQAEQEAFQRSSI----------FNWKT--VLGTFAVGGTCLAALFYIKKIRLDEREKHRKQTA 132

  Fly    76 GKAAIGGSWELVDSQGAVRKSEDFLGKWLLIYFGFTHCPDICPDELEKMAAVVDEVE-KSPQTPA 139
            |||.|||.|||:::.|.:..|::..|.|||:|||||:||||||||:|||..||:.:| |...||.
Worm   133 GKARIGGEWELMNTDGKMEGSQELRGNWLLMYFGFTNCPDICPDEIEKMVKVVEIIEAKKDATPI 197

  Fly   140 VQPIFITVDPERDSKEVVAKYVKEFSPKLLGLTGTVEQIRKVCKAFRVYFSAGPR--DEDNDYIV 202
            | |:||:|||||||...|.:|..|||.||.|.|||.||:.||.|.||||.|.|||  .:::||||
Worm   198 V-PVFISVDPERDSVARVKEYCSEFSNKLRGFTGTTEQVNKVAKTFRVYHSQGPRTNKQEDDYIV 261

  Fly   203 DHTIIMYLVNPDGEFVDYYGQNRDKDQCVASILVNIAKWNSMNKK 247
            |||:||||::|.|:|.|||||||..::....|.:.:.|:.:.|:|
Worm   262 DHTVIMYLIDPSGQFHDYYGQNRKAEEIANVIEMKVLKYQAQNRK 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Scox	NP_608884.1	SCO1-SenC	81..217	CDD:396962	81/138 (59%)
sco-1	NP_494755.1	SCO	137..281	CDD:239266	85/144 (59%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159934
Domainoid	1	1.000	172	1.000	Domainoid score	I2244
eggNOG	1	0.900	-	-		E1_COG1999
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3374
Inparanoid	1	1.050	218	1.000	Inparanoid score	I2307
Isobase	1	0.950	-	0	Normalized mean entropy	S1273
OMA	1	1.010	-	-		QHG51910
OrthoDB	1	1.010	-	-		D1462537at2759
OrthoFinder	1	1.000	-	-		FOG0002408
OrthoInspector	1	1.000	-	-		oto18874
orthoMCL	1	0.900	-	-		OOG6_100983
Panther	1	1.100	-	-	LDO	PTHR12151
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1293
SonicParanoid	1	1.000	-	-		X1597
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	17	16.790