DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon25Biii and zgc:100868

DIOPT Version :9

Sequence 1:	NP_608881.1	Gene:	Jon25Biii / 33706	FlyBaseID:	FBgn0031653	Length:	258	Species:	Drosophila melanogaster
Sequence 2:	XP_005164187.1	Gene:	zgc:100868 / 554458	ZFINID:	ZDB-GENE-040801-33	Length:	654	Species:	Danio rerio

Alignment Length:	273	Identity:	86/273 - (31%)
Similarity:	135/273 - (49%)	Gaps:	32/273 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKVFLAILALAVASASAFDEKVFVKDLPKATKIEGRITNGYAAPEGKAPYTVGLGFSGGWWCGGS 65
            ||:.:..:||.:|..:..|.::   |:.....:..||..|..||.|..|:.|.|...|..:||||
Zfish     4 MKIHIVGVALTIALLTGCDAQL---DVCGTAPLNSRIVGGQNAPVGAWPWQVSLQRDGSHFCGGS 65

  Fly    66 IIAHDWVLTAEHCIGDAAS--VIVYFG----ATWRTNAQFTHTVGNGNFIKHSN-------ADIA 117
            :|.:.|:|||.||..:.::  ::||.|    |::.:   ::.:....|.|||.|       .||.
Zfish    66 LINNQWILTAAHCFPNPSTTGLLVYLGLQKLASFES---YSMSSAVSNIIKHPNYNSDTEDNDIT 127

  Fly   118 LIRIPH-VDFWHMVNKVELPSYNDRYNNYNEWWAVACGWGGTYDG--SPLPDWLQCVDLQIVHNE 179
            |:::.. |.|.:.:..:.|.:.:..:.|....|..  |||.|..|  .|.|..||.|.:.||.|.
Zfish   128 LLQLASTVSFSNYIRPICLAASDSTFFNGTLVWIT--GWGNTATGVSLPSPGTLQEVQVPIVGNR 190

  Fly   180 ECGWTYG--SVGDNVICTRTVD-GKSICGGDSGGPLVTHDGSKLV--GVSNFVSSNGC-QSGAPA 238
            :|...||  .:.||::|...:. ||..|.||||||:|:..||..:  |:.:|  ..|| |...|.
Zfish   191 KCNCLYGVSKITDNMVCAGLLQGGKDSCQGDSGGPMVSKQGSVWIQSGIVSF--GTGCAQPNFPG 253

  Fly   239 GFQRVTYHLDWIR 251
            .:.||:.:..||:
Zfish   254 VYTRVSKYQSWIQ 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon25Biii	NP_608881.1	Tryp_SPc	36..250	CDD:214473	77/235 (33%)
Jon25Biii	NP_608881.1	Tryp_SPc	37..253	CDD:238113	78/237 (33%)
zgc:100868	XP_005164187.1	Tryp_SPc	36..265	CDD:214473	77/235 (33%)
		Tryp_SPc	37..267	CDD:238113	78/237 (33%)
		Tryp_SPc	331..509	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910