DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon25Biii and Tmprss9

DIOPT Version :9

Sequence 1:	NP_608881.1	Gene:	Jon25Biii / 33706	FlyBaseID:	FBgn0031653	Length:	258	Species:	Drosophila melanogaster
Sequence 2:	XP_006513905.2	Gene:	Tmprss9 / 432478	MGIID:	3612246	Length:	1342	Species:	Mus musculus

Alignment Length:	249	Identity:	70/249 - (28%)
Similarity:	108/249 - (43%)	Gaps:	33/249 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 ATKIEGRITNGYAAPEGKAPYTVGLGFSGGWWCGGSIIAHDWVLTAEHCIGDAASVIVYFGATWR 94
            |.:..|||..|..|..|:.|:.|.|..:...:||.:||...|:::|.||..:...     .|.|.
Mouse   449 AWRSAGRIVGGVEAAPGEFPWQVSLRENHEHFCGATIIGARWLVSAAHCFNEFQD-----PAQWA 508

  Fly    95 TNAQFTHTVGNG---------NFIKH-------SNADIALIRIPH-VDFWHMVNKVELPSYNDRY 142
            ..|...|..|:.         ...||       ::.|:|::.:.. :.|...|....||:....:
Mouse   509 AQAGSVHLSGSEASAVRTRVLRIAKHPAYDADTADFDVAVLELARPLPFGRYVQPACLPAATHVF 573

  Fly   143 NNYNEWWAVACGWGGTY---DGSPLPDWLQCVDLQIVHNEECGWTYG-SVGDNVICTRTVDGK-S 202
            ....:  .:..|||  |   |....|:.||...::::....|...|| |:.|.::|...:||| .
Mouse   574 PPGKK--CLISGWG--YLKEDFLVKPEVLQKATVELLDQSLCSSLYGHSLTDRMVCAGYLDGKVD 634

  Fly   203 ICGGDSGGPLVTHDGSKLVGVSNFVS-SNGC-QSGAPAGFQRVTYHLDWIRDHT 254
            .|.||||||||..:.|....::..|| ..|| ::..|..:.|||...|||.:.|
Mouse   635 SCQGDSGGPLVCEEPSGRFFLAGIVSWGIGCAEARRPGVYTRVTRLRDWILEVT 688

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon25Biii	NP_608881.1	Tryp_SPc	36..250	CDD:214473	65/237 (27%)
Jon25Biii	NP_608881.1	Tryp_SPc	37..253	CDD:238113	66/239 (28%)
Tmprss9	XP_006513905.2	SEA	285..365	CDD:366610
		LDLa	407..442	CDD:238060
		Tryp_SPc	455..684	CDD:214473	65/237 (27%)
		Tryp_SPc	756..984	CDD:214473
		Tryp_SPc	1085..1336	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910