DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15625 and SAMD15

DIOPT Version :9

Sequence 1:	NP_608872.1	Gene:	CG15625 / 33694	FlyBaseID:	FBgn0031644	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	NP_001010860.1	Gene:	SAMD15 / 161394	HGNCID:	18631	Length:	674	Species:	Homo sapiens

Alignment Length:	222	Identity:	56/222 - (25%)
Similarity:	88/222 - (39%)	Gaps:	47/222 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 YGIADTKFLHQKVKKKTKIRSDMAPTKFQRNEFLKGCPKYDGDDI--------PIQ--------- 52
            |.:.:.:..|::.|:.....||    ||::..:..|..:...:.|        |:|
Human   432 YSVGNDELEHREPKRGKLSLSD----KFRKEYYALGSLRESEESIGTHYEFLQPLQKLLNVSEEC 492

  Fly    53 -FRTTPDSLVELSIIVVDKLPLPSIFE-------------------------WDDMDIRRWINGY 91
             :....:|..|||..|.:|..:....|                         ||..::..||:..
Human   493 SYSDPSESQTELSEFVHEKEVVDLSQELKERVSEDDETQPEKGTELQFEHLNWDPEEVAEWISQL 557

  Fly    92 GYPQYMNTFRVNMITGRKLLLLDASALCAMNIKNFDHIRHISYGIRMLFHFELTKFSSSISLPDE 156
            |:|||...|..|.|:||||:.::.|.|..|.|.||:.::.||...:.|...|...|..|||||..
Human   558 GFPQYKECFITNFISGRKLIHVNCSNLPQMGITNFEDMKAISRHTQELLEIEEPLFKRSISLPYR 622

  Fly   157 KPNELYLLFHTQTGVNYDEVRRSDLYR 183
            ....|||.....||:..|.:..|:..:
Human   623 DIIGLYLEQKGHTGIKSDSLTLSEFVK 649

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15625	NP_608872.1	SAM_Samd14	77..143	CDD:188929	25/90 (28%)
CG15625	NP_608872.1	SAM	78..139	CDD:197735	24/85 (28%)
SAMD15	NP_001010860.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..448		3/15 (20%)
		ftsN	137..>310	CDD:274041
		SAM_Samd14	543..609	CDD:188929	24/65 (37%)
		SAM	544..607	CDD:197735	24/62 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	52	1.000	Domainoid score	I11485
eggNOG	1	0.900	-	-		E1_2CMVG
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0009897
OrthoInspector	1	1.000	-	-		otm40460
orthoMCL	1	0.900	-	-		OOG6_109459
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5600
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	7	6.790