Protein Alignment CG3355 and KLK12

DIOPT Version :10

• Sequence 1: NP_608848.1
• Gene: CG3355 / 33667
• FlyBaseID: FBgn0031619
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: NP_062544.1
• Gene: KLK12 / 43849
• HGNCID: 6360
• Length: 254
• Species: Homo sapiens
• Alignment Length: 254
• Identity: 87/254 - (34%)
• Similarity: 125/254 - (49%)
• Gaps: 53/254 - (20%)

  Fly    66 CFCG-----TPNVNRIVGGQQVRSNKYPWTAQLVKGRHYPRLFCGGSLINDRYVLTAAHCVHGNR 125
            |..|     ||   :|..|.:...|..||...|.:|   ..|.|||.||:.|:||||||| .|:|
Human    10 CVLGLSQAATP---KIFNGTECGRNSQPWQVGLFEG---TSLRCGGVLIDHRWVLTAAHC-SGSR 67

  Fly   126 DQITI---RLLQIDRSSRDPGIVRKVVQTTVHPNY--DPNRIVNDVALLKLESPVPLTGNMRPVC 185
            ..:.:   .|.|:|.:.:    :|....:..||.|  ......:|:.||:|..||.:|.:::|:.
Human    68 YWVRLGEHSLSQLDWTEQ----IRHSGFSVTHPGYLGASTSHEHDLRLLRLRLPVRVTSSVQPLP 128

  Fly   186 LPEANHNFDGKTA----VVAGWGLIKEGGVTSNY--------LQEVNVPVITNAQCRQTRYKDKI 238
            ||.     |..||    .|:|||:       :|:        ||.:|:.::::|.|... |..:|
Human   129 LPN-----DCATAGTECHVSGWGI-------TNHPRNPFPDLLQCLNLSIVSHATCHGV-YPGRI 180

  Fly   239 AEVMLCAGLVQQGGKDACQGDSGGPLIVNEGRYKLAGVVSFGY--GCAQKNAPGVYARV 295
            ...|:|||.|.  |:|||||||||||:...   .|.|:||:|.  .|.|...||||..:
Human   181 TSNMVCAGGVP--GQDACQGDSGGPLVCGG---VLQGLVSWGSVGPCGQDGIPGVYTYI 234

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3355	NP_608848.1	Tryp_SPc	76..305	CDD:238113	83/239 (35%)
KLK12	NP_062544.1	Tryp_SPc	22..236	CDD:238113	83/239 (35%)