Protein Alignment CG3355 and TMPRSS11B

DIOPT Version :10

• Sequence 1: NP_608848.1
• Gene: CG3355 / 33667
• FlyBaseID: FBgn0031619
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: NP_872308.2
• Gene: TMPRSS11B / 132724
• HGNCID: 25398
• Length: 416
• Species: Homo sapiens
• Alignment Length: 294
• Identity: 107/294 - (36%)
• Similarity: 150/294 - (51%)
• Gaps: 29/294 - (9%)

  Fly    27 HQTLAQQFADVVDVVDPAEQSIKAVRPPKSRNQCTAKQNCFCGTPNVNRIVGGQQVRSNK----- 86
            ||.|....|....|  ||  |||.:...|:.::... .|| ||....|.|:.|.::.:.|
Human   136 HQMLKNNMASWNAV--PA--SIKLMEISKAASEMLT-NNC-CGRQVANSIITGNKIVNGKSSLEG 194

  Fly    87 -YPWTAQLV-KGRHYPRLFCGGSLINDRYVLTAAHCV--HGNRDQITIRL-LQIDRSSRDPGIVR 146
             :||.|.:. |||||    ||.|||:.|::|:||||.  ..|....|:.. :.:::    |.:.|
Human   195 AWPWQASMQWKGRHY----CGASLISSRWLLSAAHCFAKKNNSKDWTVNFGIVVNK----PYMTR 251

  Fly   147 KVVQTTVHPNYDPNRIVNDVALLKLESPVPLTGNMRPVCLPEANHNF-DGKTAVVAGWGLIKEGG 210
            ||.....|.||....:.:|:||::|...|..|..:|.:|||||.... :....||.|||.:...|
Human   252 KVQNIIFHENYSSPGLHDDIALVQLAEEVSFTEYIRKICLPEAKMKLSENDNVVVTGWGTLYMNG 316

  Fly   211 VTSNYLQEVNVPVITNAQCRQT-RYKDKIAEVMLCAGLVQQGGKDACQGDSGGPLIVNEGR--YK 272
            .....|||..:.:|.|..|..: .|...:.:.|||||.: .|..||||.||||||...:.|  :.
Human   317 SFPVILQEDFLKIIDNKICNASYAYSGFVTDTMLCAGFM-SGEADACQNDSGGPLAYPDSRNIWH 380

  Fly   273 LAGVVSFGYGCAQKNAPGVYARVSKFLDWIRKNT 306
            |.|:||:|.||.:||.||||.||:.:.:||...|
Human   381 LVGIVSWGDGCGKKNKPGVYTRVTSYRNWITSKT 414

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3355	NP_608848.1	Tryp_SPc	76..305	CDD:238113	90/242 (37%)
TMPRSS11B	NP_872308.2	SEA	45..142	CDD:460188	3/5 (60%)
		Tryp_SPc	185..413	CDD:238113	88/236 (37%)