Protein Alignment CG3355 and KLK8

DIOPT Version :10

• Sequence 1: NP_608848.1
• Gene: CG3355 / 33667
• FlyBaseID: FBgn0031619
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: NP_653088.1
• Gene: KLK8 / 11202
• HGNCID: 6369
• Length: 305
• Species: Homo sapiens
• Alignment Length: 243
• Identity: 82/243 - (33%)
• Similarity: 130/243 - (53%)
• Gaps: 31/243 - (12%)

  Fly    74 NRIVGGQQVRSNKYPWTAQLVKGRHYPRLFCGGSLINDRYVLTAAHCVHGNRDQITIRLLQIDRS 138
            ::::||.:.:.:..||.|.|.:|:   :|.|||.|:...:|||||||   .:.:.|:||......
Human    76 DKVLGGHECQPHSQPWQAALFQGQ---QLLCGGVLVGGNWVLTAAHC---KKPKYTVRLGDHSLQ 134

  Fly   139 SRD-PGIVRKVVQTTVHPNYDPNRIV---NDVALLKLESPVPLTGNMRPVCLPEANH-NFDGKTA 198
            ::| |.....|||:..||.|:.:.:.   :|:.||:|.....|...::|:.|  |:| ...|:..
Human   135 NKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISL--ADHCTQPGQKC 197

  Fly   199 VVAGWGLIKEGGVTS---NYLQEVN---VPVITNAQCRQTRYKDKIAEVMLCAGLVQQGGKDACQ 257
            .|:|||.     |||   |:...:|   |.:....:| :..|..:|.:.|:|||  ...|.|.||
Human   198 TVSGWGT-----VTSPRENFPDTLNCAEVKIFPQKKC-EDAYPGQITDGMVCAG--SSKGADTCQ 254

  Fly   258 GDSGGPLIVNEGRYKLAGVVSFGYG-CAQKNAPGVYARVSKFLDWIRK 304
            |||||||:.:..   |.|:.|:|.. |.:.:.||||..:.::||||:|
Human   255 GDSGGPLVCDGA---LQGITSWGSDPCGRSDKPGVYTNICRYLDWIKK 299

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3355	NP_608848.1	Tryp_SPc	76..305	CDD:238113	82/241 (34%)
KLK8	NP_653088.1	Tryp_SPc	77..297	CDD:214473	79/238 (33%)