Protein Alignment Traf4 and Traf3

DIOPT Version :10

• Sequence 1: NP_477416.1
• Gene: Traf4 / 33638
• FlyBaseID: FBgn0026319
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: XP_038968511.1
• Gene: Traf3 / 362788
• RGDID: 1304633
• Length: 610
• Species: Rattus norvegicus
• Alignment Length: 523
• Identity: 136/523 - (26%)
• Similarity: 206/523 - (39%)
• Gaps: 162/523 - (30%)

  Fly   117 DELRKLKGHLNACKHDATQCPN----------------KCGAQIPRIMMTDHLQYTCTMRRTRC- 164
            |:.:..|..|..|....|:|.:                ||.|....|:.....:..|..|....
  Rat    91 DKYKCEKCRLVLCNPKQTECGHRFCESCMAALLSSSSPKCTACQESIIKDKVFKDNCCKREILAL 155

  Fly   165 -EFCQSEFSGAGLEEH----------NGSCGQEPVYC-EAKCGQRILRGRMTLHKSKDCAKRLRR 217
             .:|::|  |.|..|.          ...|..|.:.| .|.|.:::||..:..|..|.|..|...
  Rat   156 QIYCRNE--GRGCVEQLTLGHLLVHLKNECQFEELPCLRADCKEKVLRRDLRDHVEKACKYREAT 218

  Fly   218 CAHCQREFSADTLPLHA-AQCPRAPLACPQRCDAGPIPRGELEAHLRDECQSLAVSCSFKEAGCR 281
            ||||:.:....||..|. ..||...::||.:|....:.|.||.||| .||.:...:||||..||.
  Rat   219 CAHCKSQVPMITLQKHEDTDCPCVVVSCPHKCSVQTLLRSELSAHL-SECVNAPSTCSFKRYGCV 282

  Fly   282 FKGPRQMLEAHLESNAAAHLSLM----------VAL----SSRQGQQIQML-------------- 318
            |:|..|.::||..|:|..|::|:          |:|    |..:.:.||.|
  Rat   283 FQGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQ 347

  Fly   319 ---------------------------------------------KSAVSKL------------- 325
                                                         ||:|..|
  Rat   348 KEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRVTELESVDKS 412

  Fly   326 ----------------------------------------SINYTGTLLWKITDWSAKMAEARGK 350
                                                    :.:|.|.|:|||.|:..:..||...
  Rat   413 AGQAARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMG 477

  Fly   351 DGLELVSPPFYTSQYGYKLQASMFLNGNGPGENTHVSVYIKVLPGEYDALLKWPFSHSITFTLFE 415
            ..|.|.|.||||..:|||:.|.::|||:|.|:.||:|::..::.|||||||.|||...:|..|.:
  Rat   478 KTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMD 542

  Fly   416 QGAQSGQGGVAESFVPDPTWENFQRPSNEPDQLGFGFPRFISHELLHSRPFIKGDTVFLRVKVDP 480
            ||  |.:..:.::|.|||...:|::|:.|.: :..|.|.|::..:|.:..:||.||:|::|.||.
  Rat   543 QG--SSRRHLGDAFKPDPNSSSFKKPTGEMN-IASGCPVFVAQTVLENGTYIKDDTIFIKVIVDT 604

  Fly   481 SKI 483
            |.:
  Rat   605 SDL 607

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Traf4	NP_477416.1	PLN03086	<109..206	CDD:178635	24/117 (21%)
		zf-TRAF	233..292	CDD:280357	23/59 (39%)
		MATH_TRAF4	331..479	CDD:239750	59/147 (40%)
Traf3	XP_038968511.1	RING-HC_TRAF3	93..134	CDD:438302	8/40 (20%)
		zf-TRAF	178..234	CDD:280357	17/55 (31%)
		zf-TRAF	239..289	CDD:280357	21/50 (42%)
		Mplasa_alph_rch	<300..>410	CDD:275316	12/109 (11%)
		MATH_TRAF3	420..605	CDD:239746	62/187 (33%)