Protein Alignment capu and Frl

DIOPT Version :10

• Sequence 1: NP_001137784.1
• Gene: capu / 33611
• FlyBaseID: FBgn0000256
• Length: 1361
• Species: Drosophila melanogaster
• Sequence 2: NP_729954.2
• Gene: Frl / 39561
• FlyBaseID: FBgn0267795
• Length: 1183
• Species: Drosophila melanogaster
• Alignment Length: 1363
• Identity: 284/1363 - (20%)
• Similarity: 450/1363 - (33%)
• Gaps: 422/1363 - (30%)

  Fly   151 QRQHHHHHHHIHNAHESHHH-----------------------YPYDRRSLCTSCSSNDSLFTDP 192
            |.||.|.|.|.|:....|.|                       |.:.|:....|.|......||.
  Fly    19 QLQHPHSHAHHHSMRNGHQHNGSISSGTLQKQDLRYDIGCSSQYQHVRQPSLRSRSQQPMPTTDE 83

  Fly   193 VD-----------------------------------ELIISK----HYLNTAAKEHNNPKAKRD 218
            :|                                   |::.:|    ||| :..:.:.:|||.|.
  Fly    84 LDRRFAKVLASMDLPPDKAKLLRNYDDEKKWDMICDQEMVQAKDPPSHYL-SKLRTYLDPKASRS 147

  Fly   219 RPLSEISVTSVDTLSPNTAKAVLELQKRCRADKLACLSLTRVTYLSI-ANDLQEVEEPDRASILH 282
            ..|...               ....|||....:.....:.|...:|: .|.::.|:|     .|.
  Fly   148 HRLYLF---------------YFLCQKRKMVGESTSTQVLRDLEISLRTNHIEWVKE-----FLD 192

  Fly   283 DTDLLVAPNSPAESSPDEELMALQL---GKKLAQVL----------GSGAGSPLTPGTMEPCAAG 334
            ||      |...::..|.....||:   .::|..||          ..|.|..:..|.....:.|
  Fly   193 DT------NQGLDALVDYLSFRLQMMRHEQRLQGVLCASEERLNLTNGGDGGEIVMGNSSSVSPG 251

  Fly   335 -----------SGSPLANGELFNVSKAKKVELQNLSSRFTAAVTQTPPGVTSSTPNESGVTGPAG 388
                       :|..||||              .|.||....::.             |...|.
  Fly   252 GGGGLLSHGNSTGHGLANG--------------TLDSRQQHTMSY-------------GFLRPT- 288

  Fly   389 PLGATTSSPSLETQSTVIISFKSSQTPVQSQTNSAASENVEDDTAPLPLPPPPPGFGTPTTPLLS 453
             :.....||||:.:|..|.....          .||::::.                      :|
  Fly   289 -IADALDSPSLKRRSRHIAKLNM----------GAATDDIH----------------------VS 320

  Fly   454 SNVLKKVA------SFTVEKSSAGNNSSNPPNLCPTSDETTLLATPCSSSLTVATLPPEIAVGAA 512
            ...|:.:.      :..::...|.|        |       :..:....||....|..|:.  ||
  Fly   321 IMCLRAIMNNKYGFNMVIQHREAIN--------C-------IALSLIHKSLRTKALVLELL--AA 368

  Fly   513 AGGVAGGAGSRRGSSYVPEKLSFAAYEKFEGQMLIKWLISTMQSNPKSSSGDANQELFN----TL 573
            ...|.||.....||.   :.......||...|.|:::.:              |.|.||    ..
  Fly   369 ICLVKGGHEIILGSF---DNFKDVCQEKRRFQTLMEYFM--------------NFEAFNIDFMVA 416

  Fly   574 ALQFCNNLKYVGVLKQISNEHLDCGFSPYEMYQWTHTEQPTTSLPLTPGKLDKVAAWPFSSTPSG 638
            .:||.|.:.:                |..:|....|.:...|:|     .|||..        ..
  Fly   417 CMQFMNIVVH----------------SVEDMNYRVHLQYEFTAL-----GLDKYL--------ER 452

  Fly   639 IRALESASLASLGAGGVAGSLATIATASTASSDNQKTLQQILKKRLLNCTTLAEVHAVVNELLSS 703
            ||..||..|               ....:|..||...:..:::......:.|..|..:.::|...
  Fly   453 IRLTESEEL---------------KVQISAYLDNVFDVAALMEDSETKTSALERVQELEDQLERE 502

  Fly   704 VDEPPRRPSKRCVNLTELLNAS-------------------EATVYEYNKTGAEGCVKS------ 743
            :|    |.|:......||.:.|                   |.||.:......|..:|.
  Fly   503 ID----RNSEFLYKYAELESESLTLKTEREQLAMIRQKLEEELTVMQRMLQHNEQELKKRDTLLH 563

  Fly   744 FTDAETQTESEDCEGTCKCGQSSTKVSDNESAKEDGEKPHAVAPPPPP-PPPPLHAFVAPPPPPP 807
            ..:.|.||.|.....:...|..|.......:....|.....:.||||| |..|..:..|||||||
  Fly   564 TKNMELQTLSRSLPRSASSGDGSLANGGLMAGSTSGAASLTLPPPPPPMPASPTASSAAPPPPPP 628

  Fly   808 PPPPPPPPLANYGAPP--PPPPPPPGS--GSAPPPPPPAPIEGGGGIPPPPPPMSASPSKTTISP 868
            |.||.|||      ||  .|...|.||  .:||.||...|:.  ....|||||::..
  Fly   629 PAPPAPPP------PPGFSPLGSPSGSLASTAPSPPHAPPML--SSFQPPPPPVAGF-------- 677

  Fly   869 APLPDPAEGNWFHRTNTMRKSAVNPPKPMRP-LYWTRIVTSAPPAPRPPSVANSTDSTENSGSSP 932
            .|.||.|        .|:::..  |.|...| |.|..:    .|.....::.|..|
  Fly   678 MPAPDGA--------MTIKRKV--PTKYKLPTLNWIAL----KPNQVRGTIFNELD--------- 719

  Fly   933 DEPPAANGADAPPTAPPATKEIWTEIEETPLDNIDEFTELF-----------SRQAIAPVSKPKE 986
            ||                  :|:.:|:      .:||.|.|           |.......|....
  Fly   720 DE------------------KIFKQID------FNEFEERFKIGIGGALRNGSNGTEVDGSLQSS 760

  Fly   987 LKVKRAKSIKVLDPERSRNVGIIWRSLHVPSSEIEHAIYHIDTSVVSLEALQHMSNIQATEDELQ 1051
            .:.||..::.:|:..|.||:.|..|.|.:|..::..||:.:|...:|||.::.:..:..|:.|::
  Fly   761 KRFKRPDNVSLLEHTRLRNIAISRRKLGMPIDDVIAAIHSLDLKKLSLENVELLQKMVPTDAEVK 825

  Fly  1052 RIKE---AAGGDIPLDHPEQFLLDISLISMASERISCIVFQAEFEESVTLLFRKLETVSQLSQQL 1113
            ..||   .......|...::|:|.:|.:...|.:::.:.:...|.:||.|:..::::::..|..|
  Fly   826 SYKEYIIERKDQQLLTEEDKFMLQLSRVERISSKLAIMNYMGNFVDSVHLISPQVQSIAGASTSL 890

  Fly  1114 IESEDLKLVFSIILTLGNYMNGGNRQRGQADGFNLDILGKLKDVKSKESHTTLLHFIVRTYIAQR 1178
            .:|...|.|..|:|..|||:|  :.:||.|.||.|..|..|.|.||.:..::|||:||.|
  Fly   891 KQSRKFKAVLEIVLAFGNYLN--SNKRGPAYGFKLQSLDTLIDTKSTDKRSSLLHYIVAT----- 948

  Fly  1179 RKEGVHPLEIRLPIPEPADVE-------RAAQMDFEEVQQQIFDLNKKF-LGCKRTTAKVLAASR 1235
                     ||...||..:.|       :||.:..|.|...:.:|.|.. |..|....:|..|.
  Fly   949 ---------IRAKFPELLNFESELYGTDKAASVALENVVADVQELEKGMDLVRKEAELRVKGAQ- 1003

  Fly  1236 PEIMEPFKSKMEEFVEGADKSMAKLHQSLDECRDLFLETMRFYHFSPKACTLTLAQCTPDQFFEY 1300
                   ...:.:|:..::..:.|:...|...::.|.|.:.::..|.:       ......||..
  Fly  1004 -------THILRDFLNNSEDKLKKIKSDLRHAQEAFKECVEYFGDSSR-------NADAAAFFAL 1054

  Fly  1301 WTNFTNDFKDIWKKEITSLLNE-----LMKKSKQAQIESRRNVSTKVEK---SGRISLKERML 1355
            ...||..||...::....|..|     ...|.:..|:..|..|:.|.::   :|.:||:|.::
  Fly  1055 IVRFTRAFKQHDQENEQRLRLEKAAALAASKKENDQVLMRNKVNQKKQQLPSNGALSLQEAVI 1117

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
capu	NP_001137784.1	FH2	888..1315	CDD:214697	102/449 (23%)
Frl	NP_729954.2	Drf_GBD	77..371	CDD:461886	64/398 (16%)
		Drf_FH3	374..567	CDD:461885	45/257 (18%)
		FH2	687..1063	CDD:396655	100/445 (22%)