Protein Alignment capu and Diaph2

DIOPT Version :10

• Sequence 1: NP_001137784.1
• Gene: capu / 33611
• FlyBaseID: FBgn0000256
• Length: 1361
• Species: Drosophila melanogaster
• Sequence 2: NP_001414307.1
• Gene: Diaph2 / 317189
• RGDID: 1564399
• Length: 1101
• Species: Rattus norvegicus
• Alignment Length: 734
• Identity: 185/734 - (25%)
• Similarity: 317/734 - (43%)
• Gaps: 188/734 - (25%)

  Fly   674 KTLQQILKKRLLNCTTLAEVHAVVNELLSSVDEPPRRPSKR-----------CVNLTELLNASEA 727
            |.:::.:.:.:|:|:.:               :|..:..:|           |||..: :..||.
  Rat   456 KIIEECVSQIVLHCSGM---------------DPDFKYRQRIDFDFTHLIDACVNKAK-VEESEQ 504

  Fly   728 TVYEYNKTGAEGCVKSFT---DAETQTESEDCEGTCKCGQSSTKVSDNESAKEDGEKPHAVAPPP 789
            ...|::|...|    .||   :|:.:.:..|         ...|..::|..:...:.|.: |.|.
  Rat   505 KAMEFSKKFDE----EFTARQEAQAEIQKRD---------EKIKELESEIQQLQAQGPGS-AFPG 555

  Fly   790 PPPPPPLHAFVAPPPPPPPPPPPPPPLANYGAPPPPPPPPPGSGSAPPPPP--PAPIEGGGGIPP 852
            |||||||..  |.|.|||||||||.|    |..||||||.|  |:||||||  .||:       .
  Rat   556 PPPPPPLPG--AGPCPPPPPPPPPLP----GVGPPPPPPLP--GTAPPPPPLFGAPL-------L 605

  Fly   853 PPPPMSASPSKTTISPAPLPDPAEGNWFHRTNTMRKSAVNPPKPMRPLYWTRIVTSAPPAPRPPS 917
            ||||...:||        ||.|.|..:    ...:|...||...|:.:.|::|      .||
  Rat   606 PPPPGGITPS--------LPGPVELPY----GMKQKKLYNPEVSMKRINWSKI------EPR--- 649

  Fly   918 VANSTDSTENSGSSPDEPPAANGADAPPTAPPATKEIWTEIEETPLDNIDEFTELFSRQAIAPVS 982
                 |.:||.                         :|.:::|...:|.|.|.:|       .::
  Rat   650 -----DLSENC-------------------------VWLKLKEEKYENPDLFAKL-------ALT 677

  Fly   983 KPKELK----------------VKRAKSIKVLDPERSRNVGIIWRSLHVPSSEIEHAIYHIDTSV 1031
            .|.::|                .|:.|.:::||.:.::|:.|...|..:|..||::.|..::..:
  Rat   678 FPSQMKGQRHGETSEENRIGPQKKKMKELRILDTKTAQNLSIFLGSYRMPYEEIKNIILEVNEEL 742

  Fly  1032 VSLEALQHMSNIQATEDELQRIKEAAGGDIPLDHPEQFLLDISLISMASERISCIVFQAEFEESV 1096
            :|...:|::......::.|:.:.:.......|..||||.:.:|.::|...|::.|:|:..|||.|
  Rat   743 LSEALIQNLVKYLPEQNVLRELAQLKNEYDDLCEPEQFGVVMSTVNMLRPRLTSILFKLTFEEHV 807

  Fly  1097 TLLFRKLETVSQLSQQLIESEDLKLVFSIILTLGNYMNGGNRQRGQADGFNLDILGKLKDVKSKE 1161
            ..:...:..|:...::|.:||....:..:||.:|||||.|:| ..|:.||.::.|.|:||.||.:
  Rat   808 NNIKPSIIAVTLACEELKKSESFNRLLELILLVGNYMNSGSR-NAQSLGFKINFLCKIKDTKSAD 871

  Fly  1162 SHTTLLHFIVRTYIAQRRKEGVHPLEIRLPIPEPAD-VERAAQMDFEEVQQQIFDLNKKFLGCKR 1225
            ..||||||:......|.|       :| |..||..: ||.|:::..:.::..:..:.:..|..:.
  Rat   872 QKTTLLHFLAEICDEQHR-------DI-LKFPEELEHVESASKVSAQILKSNLVAMEQSILHLES 928

  Fly  1226 TTAKVLAASRPEIMEPFKSKMEEFVEGA----DK------SMAKLHQSLDECRDLFLETMRFYHF 1280
            .......|.  .:.:.|..||..|.:.|    ||      :|.||::||.|          ::.|
  Rat   929 NIKNFPKAE--SLHDKFVEKMMSFTQNAREQYDKLSTMHSNMLKLYESLGE----------YFIF 981

  Fly  1281 SPKACTLTLAQCTPDQFF----EYWTNFTNDFKDIWKKEITSLLNELMKKSKQAQIESRRNVSTK 1341
            .|...|:       ::||    .:.|.|....|:..|::      |:.:||::|::...:....|
  Rat   982 DPNIVTI-------EEFFGDLNTFRTLFLEALKENHKRK------EMEEKSRRAKLAKEKAEQEK 1033

  Fly  1342 VEKSGRISLKERMLMRRSK 1360
            :|:    ..|::.|:..:|
  Rat  1034 LER----QKKKKQLIDINK 1048

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
capu	NP_001137784.1	FH2	888..1315	CDD:214697	108/457 (24%)
Diaph2	NP_001414307.1	None