Protein Alignment capu and Fmnl1

DIOPT Version :10

• Sequence 1: NP_001137784.1
• Gene: capu / 33611
• FlyBaseID: FBgn0000256
• Length: 1361
• Species: Drosophila melanogaster
• Sequence 2: NP_001426911.1
• Gene: Fmnl1 / 287746
• RGDID: 1311042
• Length: 1101
• Species: Rattus norvegicus
• Alignment Length: 1077
• Identity: 242/1077 - (22%)
• Similarity: 390/1077 - (36%)
• Gaps: 292/1077 - (27%)

  Fly   402 QSTVIISFKSSQTPVQ-SQTNSAASENVED--DTAPLPLP--------PPPPGFGTPT---TPLL 452
            |.:|....:|::.... ::.|....::|||  ...|..:|        ||.|.. ||.   ..|.
  Rat   158 QCSVAYDMESTENVASGTEKNKPLEQSVEDLSKAPPSSVPKSRLTIKCPPSPRL-TPAHSRKALR 221

  Fly   453 SSNV-------------LKKVASF------------TVEKSSAGNNSSNPPNLCPTSDETTLLAT 492
            :|.:             |:.:.::            .|.:.:...|:.||.......:   |||.
  Rat   222 NSRIVSQKDDVHVCIMCLRAIMNYQSGFSLVMNHPACVNEIALSLNNKNPRTKALVLE---LLAA 283

  Fly   493 PCSSSLTVATLPPEIAVGAAAGGVAGGAGSRRGSSYVPEKLSFAAYEKFE----GQMLIKWLIST 553
            .|.                    |.||           ..:..||::.|:    .|...:.|:..
  Rat   284 VCL--------------------VRGG-----------HDIILAAFDNFKEVCGEQHRFEKLMEY 317

  Fly   554 MQSNPKSSSGDANQELFNTLALQFCNNLKYVGVLKQISNEHLDCGFSPYEMYQWTH--------- 609
            .::.      |:|.: |....:||.|.     |:..:.|    ..|..:..|::||
  Rat   318 FRNE------DSNID-FMVACMQFINI-----VVHSVEN----MNFRVFLQYEFTHLGLDLYLER 366

  Fly   610 ---TEQPTTSLPLTPGKLDKV--AAWPFSSTPSGIRALES--------ASLASLGAGGVAGSLAT 661
               ||.....:.: ...||.|  .......|.:....||.        |:|..........|:|.
  Rat   367 LRLTESDKLQVQI-QAYLDNVFDVGTLLEETETKNAVLEHMEELQEQVATLTERLRDTENDSMAK 430

  Fly   662 IATASTASSDNQKTLQQILKKRLLNCTTLAEVHAVVNELLSS--VDEPPRRPSKRCVNLTELLNA 724
            ||......|..:|.|:           ||.|..:....:::|  :.||.:.|:...|..:.|
  Rat   431 IAELEKQLSQARKELE-----------TLRERFSESTPMVTSRRIPEPEKVPAPTVVRPSAL--- 481

  Fly   725 SEATVYEYNKTG------AEGCVKS--FTDAETQTESEDCEGTCKCGQSSTKVS-DNESAKEDGE 780
             |..|.|..:.|      ..|.|.|  .......|.|.|       ...:.:|| |:.|..|  .
  Rat   482 -ELKVEELEEKGLIRILRGPGDVVSIEILPGAAATPSGD-------DAPAPRVSTDSPSTAE--S 536

  Fly   781 KPHAVAPPPPPPPPPLHAFVAPPPPP---------PPPPPPPPPLANYGAPPPPPPPPPGSGSAP 836
            .|.|.:|.|||||||      |||.|         |..||..|||....||||.||.|   |..|
  Rat   537 VPEAASPTPPPPPPP------PPPLPNLQSQQEALPSAPPLAPPLPGCAAPPPAPPLP---GDLP 592

  Fly   837 PPPPPAPIEGGGGIPPPPPPMSASPSKTTISPAPLPDPAEGNWFHRTNTMRKSAVNPPKPMRPLY 901
            |||||.|:...|.:||||||
  Rat   593 PPPPPPPLGTDGPVPPPPPP--------------------------------------------- 612

  Fly   902 WTRIVTSAPPAPRPPSVANSTDSTENSGSSPDEP-------PAANGADAPPTAPPATKEIWTEI- 958
                    ||. .||.:....|.....|....:|       |..|.....|:  ..|..::||:
  Rat   613 --------PPG-GPPDILGGQDPEIGPGVKAKKPIQTKFRMPLLNWVALKPS--QITGTVFTELN 666

  Fly   959 EETPLDNID--EFTELFSRQAIAPVSKPKELKVKRA----KSIKVLDPERSRNVGIIWRSLHVPS 1017
            :|..|..:|  :|.|.|..::..|......||.|.|    ....:::..|::|:.|..|..::.:
  Rat   667 DEKVLQELDMNDFEEQFKTKSQGPSLDISALKGKTAHKAPTKATLIEANRAKNLAITLRKGNLGA 731

  Fly  1018 SEIEHAIYHIDTSVVSLEALQHMSNIQATEDELQRIKEAAGGDIP---LDHPEQFLLDISLISMA 1079
            ..|..||...|...:||:.|:.::....|:.|...|........|   |...::|:|..|.|...
  Rat   732 DRICEAIETYDLQTLSLDFLELLTRFLPTDYERSLIARFEKEQRPMEELSEEDRFMLRFSRIQRL 796

  Fly  1080 SERISCIVFQAEFEESVTLLFRKLETVSQLSQQLIESEDLKLVFSIILTLGNYMNGGNRQRGQAD 1144
            .||::.:.|...|.::..||..:|..:...|..:..|:.|:.:..|:|..|||||  :.:||.|.
  Rat   797 PERMNTLTFLGNFPDTAQLLMPQLNAIIAASISIKSSDKLRQILEIVLAFGNYMN--SSKRGAAY 859

  Fly  1145 GFNLDILGKLKDVKSKESHTTLLHFIVRTYIAQRRKE--GVHPLEIRLPIPEPAD---VERAAQM 1204
            ||.|..|..|.::||.:...||||::|:. ||::..:  |.|           :|   :::|..:
  Rat   860 GFRLQSLDALLEMKSTDRKQTLLHYLVKV-IAEKYPQLTGFH-----------SDLHFLDKAGSV 912

  Fly  1205 DFEEVQQQIFDLNKKFLGCKRTTAKVLAASRPE-IMEPFKSKMEEFVEGADKSMAKLHQSLDECR 1268
            ..:.|           ||..|:..:.|..::.| :.:.....::||:.....:|.||.......:
  Rat   913 SLDSV-----------LGDVRSLQRGLELTQREFVRQDDCLVLKEFLRANSPTMDKLLADSKTAQ 966

  Fly  1269 DLFLETMRFYHFSPKACTLTLAQCTPDQFFEYWTNFTNDFK------DIWKKEI---TSLLNELM 1324
            :.:...:.::..:||.       .:|..||..::.||..:|      :.||||.   ||...|
  Rat   967 EAYESVVEYFGENPKT-------TSPSMFFSLFSRFTKAYKKAEQEVEQWKKEAAADTSGREE-- 1022

  Fly  1325 KKSKQAQIESRRNVSTKVEKSGRISLKERMLMRRSKN 1361
            ..:.::..::||.....:.:..|..|||.::....::
  Rat  1023 PPAPKSPPKARRQQMDLISELKRKQLKEPLIYESDRD 1059

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
capu	NP_001137784.1	FH2	888..1315	CDD:214697	103/455 (23%)
Fmnl1	NP_001426911.1	None