Protein Alignment capu and for3

DIOPT Version :10

• Sequence 1: NP_001137784.1
• Gene: capu / 33611
• FlyBaseID: FBgn0000256
• Length: 1361
• Species: Drosophila melanogaster
• Sequence 2: NP_588046.1
• Gene: for3 / 2539487
• PomBaseID: SPCC895.05
• Length: 1461
• Species: Schizosaccharomyces pombe
• Alignment Length: 1222
• Identity: 248/1222 - (20%)
• Similarity: 430/1222 - (35%)
• Gaps: 407/1222 - (33%)

  Fly   410 KSSQTPVQSQT-----NSAASENVE---DDTAPLPLPPPPPGF---GTPTTPLLSSNV-LKKVAS 462
            ::|:||::||.     :...|||..   ..:|...:    |||   ||....:||.:: ..::|:
pombe   210 RASKTPLESQIIQSLFHCLNSENCRRRYQSSAKCSV----PGFNALGTIAETVLSKSLNSARMAT 270

  Fly   463 FTVE-----------------------------KSSAGNNSSNP----PNLCPTSDETTLL---- 490
            |.::                             :.||..:|.|.    ..:|..|....::
pombe   271 FLLKFLCNKKGLSYFKAVIRAFEWLVEQKLSKTRFSAWMHSFNDVITGVRVCADSSPQAIVHMDE 335

  Fly   491 --ATPCSSSLTVATL---------PPEIAVGAAAGGVAGGAGSRRGSSYVPEKLSFAAYEKFEGQ 544
              .|.|.....||||         ||::.:..|.......||.::..                 .
pombe   336 FEDTDCLIDYLVATLALIRDLCAAPPDLQLRCALRHELLSAGLQKAI-----------------D 383

  Fly   545 MLIKW----LISTMQSNPKSSSGDANQELFNTLALQFCNNLKYVGVLKQIS---NEHLDCGFSPY 602
            .|:||    :...:|...|..:.||.:  |.:.:  ..||:....|.||::   ..|...|.:..
pombe   384 SLLKWRNRHVRDALQLLIKEHNADARR--FRSGS--DVNNVDRKCVKKQMNYREESHTPHGNTTR 444

  Fly   603 EMYQWTHTEQP-TTSLPLTPGKLDKVAAWP-------------------------FSSTPSGIRA 641
            :      |..| :.:.|.||   ::.|.|.                         |.:.|...:.
pombe   445 K------TSTPVSNNRPTTP---EQQAVWDVFQRIYTRFTGSEGSKESFIKLLEYFVTEPDNGKI 500

  Fly   642 LESASLASLGAGGVAGSLATIATASTASSDNQKTLQQILKKRLLNCTTLAE-------------- 692
            .:|..|       :..:|..:....||.:|....| .||.:|||:....||
pombe   501 QKSMQL-------LTHTLEALEGFKTAKADTNVGL-TILSQRLLDKLGTAEEIAEYKTKYNGAML 557

  Fly   693 ----VHAVVNELLSSVDEPPRRPS----------KRCVNLTELLNAS---------EATVYEYNK 734
                :...|..:||.::..||.|.          |..:||.:.|.||         .|.:..|||
pombe   558 ENKHLKEQVESMLSQLNVGPRDPMQFLKKQLDELKAELNLRDNLLASMQREFETRYRAQIQAYNK 622

  Fly   735 TGAE--------------GCV----KSF------------TDAETQTESEDCEGTCKCGQ----- 764
            ..::              |.:    |||            .||.|:..|...|.....|.
pombe   623 LQSQMEHVQNSNEQHLQPGLLNKVSKSFDSVHRRNLSQDSLDAMTEQFSYHVEPNILSGSGIPVR 687

  Fly   765 ----SSTK-VSDNESAKEDGEKPHAVAP--------------PPPPPPPPLHAFVAPPPPPPP-P 809
                |.|: :.::.|..|....|..:.|              ..||||||  |.:.|.|.|.| |
pombe   688 VHTPSKTEDLDESFSGSEISSSPSPLLPDVSDTVEEQQKLLLKSPPPPPP--AVIVPTPAPAPIP 750

  Fly   810 PPPPPPLANYGAPPPPPPPPPGSGSAPPPPPPAPIEGGGGIPPPPPPMSASPSKTTISPAPLPDP 874
            .|||.|:  .|.||||||||..:|:.||||           |||||.:||..|: ..:|||..:|
pombe   751 VPPPAPI--MGGPPPPPPPPGVAGAGPPPP-----------PPPPPAVSAGGSR-YYAPAPQAEP 801

  Fly   875 -----------AEGNWFHRTNTMRKSAVN--------------------PPKPMRPLYWTRIVTS 908
                       .:..........||:|.:                    |.:|::.::|.|:
pombe   802 EPKIDETSLTEEQKIQLEEARKQRKAADDAARAAIEKYTSIPSLRDLHKPTRPLKRVHWQRV--- 863

  Fly   909 APPAPRPPSVANSTDSTENSGSSPDEPPAANGADAPPTAPPATKEIWTE------------IEET 961
             .|.|.|                                     .::|:            |:..
pombe   864 -DPLPGP-------------------------------------NVFTKFCLNFDITAKVFIDNG 890

  Fly   962 PLDNIDEFTELFSRQAIAPVSKPKELKVKRAKSIKVLDPERSRNVGIIWRSL-HVPSSEIEH--- 1022
            .||.:||..:...|:....|    |:..:|:   .:|.....:|:.||.||: ::|..::..
pombe   891 LLDFLDEKFDNTPREDFVAV----EISDQRS---SLLPDTVEQNMAIILRSVSNMPVEDLVQKFL 948

  Fly  1023 --------AIYHID-TSVVSLEALQHMSNIQATEDELQRIKEAAGGDIPLDHPEQF--LLDISLI 1076
                    :|.:.| .|:.|..|........:|:...:..||.......|.:.|:|  |..::|.
pombe   949 VEPDFLPASILYFDRASLASTNAYTDPFIPYSTDYTKKNPKEPTADVNSLSYFEKFFVLFVVNLR 1013

  Fly  1077 SMASERISCIVFQAEFEESVTLLFRKLETVSQLSQQLIESEDLKLVFSIILTLGNYMNGGNRQRG 1141
            ....||:..:.|::.....:.:|..:::.|...|..::|.::....|.::|.:|||.   |....
pombe  1014 HYFQERMKALKFRSTLFGDLEILEVRMKEVIDTSDSIMEDKNFAEFFQVLLIIGNYF---NEPYD 1075

  Fly  1142 QADGFNLDILGKLKDVKSKESHTTLLHF---IVRTYIAQ--------RRKEGVHPLEIRLPIPEP 1195
            :|..|:|.::.:|:.::...|..||:|:   |:||...:        ::.:.|....|...:
pombe  1076 RASAFSLYMIYRLETLRDSSSALTLMHYFDEIIRTRFPELLQAESTFKKIQSVSGYNIDAMV--- 1137

  Fly  1196 ADVERAAQMDFEEVQQQIFD--LNKKFLGCKR-----TTAKVLAASRPEIME------PFKSKME 1247
            |.|: .|..:|.:.|..:.|  |:|    |.:     ....:|:...||..|      ..|:.|.
pombe  1138 AGVD-GAYDEFCDFQTSLKDGALSK----CDQHHPDDKAYDILSEWLPEAKERIRNIKKLKTDML 1197

  Fly  1248 EFVEGADKSMAKLHQSLDECRDLFLETMR-FYHFSPKACTLTLAQCTPDQFFEYWTNFTNDFKDI 1311
            ..:|...|.:.: :.|:|:.|:.|.:.:. ||..      .::|:...::.||      .:.:.|
pombe  1198 TKLENTVKYLCE-YDSIDKVRNSFFKNLNSFYEM------YSIAKAENEERFE------KEKRRI 1249

  Fly  1312 WKKEITSLLNELMKKSKQAQIESRRNV---------STKVEKSGRISLKERM 1354
            ..::...|:....|.|..|:..::|.:         :...:|:...::.|:|
pombe  1250 MSEDRDKLIRGRQKTSIVAKYRNKRELPEDSDDKQDTASKDKNSLETIDEKM 1301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
capu	NP_001137784.1	FH2	888..1315	CDD:214697	92/498 (18%)
for3	NP_588046.1	Drf_FH3	307..511	CDD:461885	42/240 (18%)
		FH2	846..1295	CDD:214697	96/520 (18%)