Protein Alignment capu and daam-1

DIOPT Version :10

• Sequence 1: NP_001137784.1
• Gene: capu / 33611
• FlyBaseID: FBgn0000256
• Length: 1361
• Species: Drosophila melanogaster
• Sequence 2: NP_503132.3
• Gene: daam-1 / 186392
• WormBaseID: WBGene00018976
• Length: 987
• Species: Caenorhabditis elegans
• Alignment Length: 774
• Identity: 160/774 - (20%)
• Similarity: 278/774 - (35%)
• Gaps: 220/774 - (28%)

  Fly   658 SLATIATASTASSDNQKT----------LQQILKKRLLNCTTLAEVHAVVNELLSSVDEPPRRPS 712
            |||...|:|..|..::.:          :.:.|..:|.:...|...|:::..|.....:....|.
 Worm   326 SLAGSCTSSDISMSSETSSPIDFESVVGMAEALHIKLNHSQALPHFHSLLQHLFMVPSDDQHVPL 390

  Fly   713 KRCVNL--------------TEL-------LNASEATVYEYNKTGAEGCVKSFTDAETQTESEDC 756
            .|..:|              |::       ::.||......|....|...|   :.|...|..|.
 Worm   391 WRLFDLILQHLTLQTTVNGMTDVNSPLQNHVDMSEILARLQNHCDYERIAK---ELEKAKEDMDL 452

  Fly   757 EGT-----------CKCGQSSTKVS-DNESAKEDGEKPHAVAPPPPPPPPPLHAFVAPPPPPPPP 809
            |.|           ...|::.:::| .:.||..        :|..|.|.|||    .||..||.|
 Worm   453 ERTRIMELENRLADFSDGRAGSRISLASTSASS--------SPSDPCPSPPL----LPPVCPPAP 505

  Fly   810 PPPPPPLANYGAPPPPPPPPPGSGSAPPPPPPAPIEGGGGIPPPPPPMSASPSKTTISPAPLPDP 874
            ||||||:                               ||:..||        |..:...|
 Worm   506 PPPPPPI-------------------------------GGLTSPP--------KDALKNVP---- 527

  Fly   875 AEGNWFHRTNTMRKSAVNPPKPMRPLYWTRIVTSAPPAPRPPSVANSTDSTENSGSSPDEPPAAN 939
                             .||..|:.|.|.|:               :.|.|..:
 Worm   528 -----------------EPPGNMKTLNWQRL---------------TLDKTRGT----------- 549

  Fly   940 GADAPPTAPPATKEIWTEIEETPLDNIDEFTELFSRQAIAPVSKPKEL--------KVKRAKSIK 996
                          :|..|::..:....:.|||....|.:...|.::.        :..:..:|.
 Worm   550 --------------VWDGIDDEKIYKQLDLTELSGCFAASSSHKDEDTDTLYGTINRRPQQANIT 600

  Fly   997 VLDPERSRNVGIIWRSLHVPSSEIEHAIYHIDTSV-VSLEALQHMSNIQATEDELQRIKEAA--- 1057
            |:||.|.:|..|:...|.:...||:.|:..:|... :..:.::.|.....|::||.:|.|:.
 Worm   601 VIDPRRYQNCTIMLSKLKLSHKEIKQAMMSMDEKCKLPKDMIEQMLKFMPTKEELTQINESVQKH 665

  Fly  1058 GGDIPLDHPEQFLLDISLISMASERISCIVFQAEFEESVTLLFRKLETVSQLSQQLIESEDLKLV 1122
            |....|...::::.:||.|....:|:.|:.....|.:.|..|...::.|.:.:....:::..:.:
 Worm   666 GSPTVLALADRYMYEISSIPRFEQRLRCLNIIRSFHDRVEALVPFIQVVLKATSSCQQNKRFRQI 730

  Fly  1123 FSIILTLGNYMNGGNRQRGQADGFNLDILGKLKDVKSK-ESHTTLLHFIVRTYIAQRRKEGVHPL 1186
            .:|||.:|||:|.|.| .|.|.||.:..:.||.|||:. .:...||||:| .:|.::     :|
 Worm   731 LTIILAIGNYLNFGKR-NGNAYGFEMASINKLADVKNALRNDRNLLHFLV-NFIEKK-----YP- 787

  Fly  1187 EIRLPIPEPADVERAAQMDFEEVQQQIFDLN------KKFLGCKRTTAKVLAASRPEIMEP---- 1241
            ::.....:.|.|..||:....|...:|.:|.      :|.|....:|.||   ..||.:.|
 Worm   788 DLTKFKKDFATVTEAARFSQSETAAEIRNLEEALLIVRKELNLLESTTKV---ELPEHIPPENDR 849

  Fly  1242 FKSKMEEFVEGADKSMAKLHQSLDECRDLFLETMRFYHFSPKACTLTLAQCTPDQFFEYWTNFTN 1306
            |....:.|:|.|......|.:...|.::.|.:..:::.:||..     ....|::||.....|.|
 Worm   850 FALVAKAFIEKATAEYHNLDKMFREMKNKFSDCAKYFCYSPSG-----GVPVPEEFFSVINKFLN 909

  Fly  1307 DFKD----IWKKEITSLLNELMKKSKQAQIESRRNVSTKVEKSGRISLKERMLMRRSKN 1361
            .|.:    :|                 |::|....:  |.:...|..|.::...||.:|
 Worm   910 TFNEYHQQLW-----------------AEVEEEEKI--KRQTIARSFLAKKSTTRRKEN 949

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
capu	NP_001137784.1	FH2	888..1315	CDD:214697	100/453 (22%)
daam-1	NP_503132.3	Drf_GBD	39..212	CDD:461886
		Drf_FH3	216..412	CDD:461885	14/85 (16%)
		FH2	524..973	CDD:214697	109/522 (21%)