Protein Alignment capu and fhod-1

DIOPT Version :10

• Sequence 1: NP_001137784.1
• Gene: capu / 33611
• FlyBaseID: FBgn0000256
• Length: 1361
• Species: Drosophila melanogaster
• Sequence 2: NP_001300416.1
• Gene: fhod-1 / 172133
• WormBaseID: WBGene00016735
• Length: 1698
• Species: Caenorhabditis elegans
• Alignment Length: 819
• Identity: 161/819 - (19%)
• Similarity: 281/819 - (34%)
• Gaps: 260/819 - (31%)

  Fly   664 TASTASSDNQKTLQQ---ILKKRLLNCTTLAEVHAVVNELLSSVDEPPRRPSKRCVNLT------ 719
            |:|..:.|.:.|:::   ..::|.|..........:.|::  .:...||.||.....::
 Worm   867 TSSGVADDKKATMRRRHDEARRRQLEHEQFTANRTLFNKI--DIGAAPRIPSPVSPTVSSWQPPV 929

  Fly   720 -ELLNASEATVYEYNKTGAEGCVKSFT-DAETQTESEDCEGTCKCGQSSTKVSDNESAKEDGEKP 782
             |.:..:.:|....|..|:   ::|.. .|..|...|:              .:||..||..|..
 Worm   930 REDIQPTTSTATNNNDIGS---IRSKNIPAPIQLVQEN--------------QENEIPKETDESE 977

  Fly   783 HAVAPPPPPPPPPL-----------HAFVAPPPPPPPPPPPPPPLA------------------- 817
            .:.:...|||..|.           .:.|||..|.|....||||.|
 Worm   978 SSKSVKAPPPSFPTLFSPTESKTMDFSEVAPQEPEPEKVAPPPPRAKIEDTGSGNSFADMLQKRA 1042

  Fly   818 ----------------------------------------------------------------- 817
                                                                             
 Worm  1043 ARSAEANRGTFEKKESEAEMQWKKAAENLEKRPLIINDLDFSQFHGVEYQQDPLQLARMAKMKEM 1107

  Fly   818 ----------NYGAPPPPPPP-----PPGSGSAPPPPPPAPIEGGGGIPPPPPPMSASPSKTTIS 867
                      ..|.|||||||     ||......|||||.     |.|||||||
 Worm  1108 AENGMRGGPVGVGVPPPPPPPSAIPLPPRLQGGIPPPPPL-----GIIPPPPPP----------- 1156

  Fly   868 PAPLPDPAEGNWFHRTNTMRKSAVNPP--KPMRPLYWTRIVTSAPPAPRPPSVANSTDSTENSGS 930
                     ||..  .|.:.:..::|.  |.:..|:|           :|.:|..
 Worm  1157 ---------GNLL--MNGINRGDISPAANKGVLKLHW-----------KPATVEQ---------- 1189

  Fly   931 SPDEPPAANGADAPPTAPPATKE---IWTEIE-ETPLDNIDEFTELF--SRQAIAPVSKPKELKV 989
                          |...|:.|:   .|..:: ..|..:..:..:||  .::..|||.|..|.|
 Worm  1190 --------------PDGIPSLKQKGSFWNTVDGAVPTFDAKKIVQLFETKKEKEAPVKKVAETK- 1239

  Fly   990 KRAKSIKVLDPERSRNVGIIWRSLHVPSSEIEHAIYHIDTSVVSLEALQH-MSNIQATEDELQ-- 1051
              .:::.||..:||:.:.|....| .|.:.|..||...|:.|::.:.::. :..:..:..|::
 Worm  1240 --TQTLSVLPLKRSQAINIGLTKL-PPINVIPAAIMKFDSLVLNKDGIEKILKTMMPSPKEIEEI 1301

  Fly  1052 RIKEAAGGDIPLDHPEQFLLDISLISMASERISCIVFQAEFEESVTLLFRKLETVSQLSQQLIES 1116
            .||.|...::.|.:.||.||.:|.|....||:...:|..:::.|...:...|..:....:::.||
 Worm  1302 EIKAAENPEMTLGNAEQLLLKLSQIPCLLERLRLWLFTLDYKNSEKDIAEPLMDMQLAMKEMEES 1366

  Fly  1117 EDLKLVFSIILTLGNYMNGGNRQRGQADGFNLDILGKLKDVKSK-ESHTTLLHFIVRTYIAQRRK 1180
            ...|:...::|.:||.::|.:     ..||.||.|.|..:||.. ..||...|  :..|:.:...
 Worm  1367 RTFKVAMGMLLAIGNSLSGTD-----IKGFYLDYLTKASEVKDPVYKHTLTYH--LAEYMVEHFS 1424

  Fly  1181 EGVHPLEIRLPIPEPADVERAAQMDFEEVQQQIFDLNKKFLGCKRTTAKVLAASRPEIMEPFKSK 1245
            ||.....      |...|.|:|::|::|:...:..|.|   .|| ::.:.||..........|.|
 Worm  1425 EGTDLYS------EFGAVARSARVDYKELLDNLIRLEK---DCK-SSWECLATISKNDNSNMKQK 1479

  Fly  1246 MEEFVEGADKSMAKLHQSLDECRDLFLETMRFYH-------FSPKACTLTLAQCTPDQFFEYWTN 1303
            :.::       :|.:.|.:.:.:.::..|...:|       :|..    .:...||:..|:..|.
 Worm  1480 INDY-------LADVAQRIHQLKAIYTVTKNRWHSFLLYFGYSVD----EIPNQTPNDVFKMVTE 1533

  Fly  1304 FTNDFKDIWKKEITSLLNELMKKSKQAQIESRRNVSTKV 1342
            |:.:::       |:....|.::.:.|:...|.....|:
 Worm  1534 FSLEYR-------TTRDKILQQRKRLAEKRERNKTRGKI 1565

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
capu	NP_001137784.1	FH2	888..1315	CDD:214697	92/445 (21%)
fhod-1	NP_001300416.1	Atrophin-1	49..>368	CDD:460830
		Formin_GBD_N	<409..468	CDD:465735
		FH2	1178..1539	CDD:418645	90/427 (21%)