Protein Alignment capu and FAM47A

DIOPT Version :10

• Sequence 1: NP_001137784.1
• Gene: capu / 33611
• FlyBaseID: FBgn0000256
• Length: 1361
• Species: Drosophila melanogaster
• Sequence 2: NP_981953.2
• Gene: FAM47A / 158724
• HGNCID: 29962
• Length: 791
• Species: Homo sapiens
• Alignment Length: 760
• Identity: 145/760 - (19%)
• Similarity: 225/760 - (29%)
• Gaps: 282/760 - (37%)

  Fly   481 CPTSDETTLLATPCSSSLTVATLPPEIAV-GAAAGGVAGGAGSRRG----SSYVPEKLSFAAY-E 539
            ||:.::|.:    |...   ..|.|:|:: |..|...:|.....:.    |...|.:|:..|: |
Human    62 CPSPEDTLV----CRRD---EFLLPKISLRGPQADPKSGQKKLLKKAALFSKLSPAQLARKAFVE 119

  Fly   540 KFEGQMLIKWLISTMQSNPKSSSGDANQELFNTLALQFCNNLKYVGVLKQISNEHLDCGFSPYEM 604
            :.|.|::.|        :|.:...:..:::...|.||         |||     |||......:.
Human   120 QVEAQLMAK--------HPLAMYPNLGEDMPPDLLLQ---------VLK-----HLDPERELEDA 162

  Fly   605 YQWTHTEQPTTSLPLTPGKLDKVAAWPFSSTPSGIRALE------SASLASLGAGGVAGSLATIA 663
            :....|::.||.:|..|||           .|.|...|:      |..|......||
Human   163 WACCETQEKTTEVPTEPGK-----------HPCGEFCLKPPETPVSHLLPEPPETGV-------- 208

  Fly   664 TASTASSDNQKTLQQILKKRLLNCTTLAEVHAVVNELLSSVDEPPRRPSKRCVNLTELLNASEAT 728
              |..|.:..||....|:                       .|||.      ..::.|......|
Human   209 --SHLSPEPPKTPVSSLR-----------------------PEPPE------TGVSHLRPEPPET 242

  Fly   729 VYEYNKTG------AEGCVKSFTDAETQTESEDCEGTCKCGQSSTKVSDNESAKEDGEKPHAVAP 787
            ...:.:.|      ....::.....:::.:.||....|:..:.:|     :...|.|:.|.....
Human   243 GVSHIRPGPPITRRRSSLLRQLLKLDSERKLEDARAPCEGREKTT-----DEPTEPGKYPCGKFC 302

  Fly   788 PPPPPPPPLHAFVAPPPPP-----PPPPPP--------------------------------PPP 815
            |.|...|..|....||..|     |.||..                                .||
Human   303 PRPFETPLSHLRQEPPKTPVSSLRPEPPETGESHLRLEHSKTRRGSSLRSEPSETGVSRLRLAPP 367

  Fly   816 LANYGAPPPPPPPPPGSGSAPPPPPPAPIEGGGGIPP----------PPPPMSAS---------- 860
            ....|:.....|...|.....|.||...:.....:||          ||.....|
Human   368 KTRRGSSLHAEPSKTGVSHLSPEPPKTEVSHLHPVPPKTGVCHLRLEPPDTSQVSNLLLYILKVL 432

  Fly   861 ----------------------PSKTTISPA--PLPDPAEGNWFH----RTNTMRKSAVN--PPK 895
                                  |::...||.  |...|.|....|    ...|.|:|:::  |||
Human   433 DSGRTLKDVWDRCEARVKKTKEPTEPHKSPCGEPCLQPPETQVSHPHPEHPKTRRRSSLHSQPPK 497

  Fly   896 PMRPLYWTRIVTSAPPAPRPPSVANSTDSTENSGSSPDEPPAANGADAPPTAPPATKEIWTEIEE 960
            ..|    |..:.|.||            .|..:.|...|||......:....||.|:.:.:...|
Human   498 TRR----TSSLRSEPP------------KTRRTSSLRSEPPKTRRTSSLGPEPPKTRRVSSLRPE 546

  Fly   961 TPLDNIDEFTELFSRQAIAP----VSKPKELKVKRAKSIKVLDPERSRNVGIIWRSLHVPSSEIE 1021
            .|...  ..:.|......||    .|:|.::   ||..||.|..|            ..||::
Human   547 LPKSR--RVSSLHPEPPKAPESHQFSEPPKI---RASYIKELLQE------------DTPSTK-- 592

  Fly  1022 HAIYHIDTSVVSLEALQHMSNIQATEDELQRIKEAAGGDIPLDHPEQFLLDISLISMASERISCI 1086
                    ..|| ::||:    :.|.::|:...:.| ||:..|
Human   593 --------ECVS-DSLQY----RYTSEKLREFFKWA-GDLGAD---------------------- 621

  Fly  1087 VFQAEFEESVTLLF------------RKLETVSQLSQQLIESEDL 1119
                  |||:..||            :|.:.|.:.|.:|..|.:|
Human   622 ------EESIRNLFDFTPKYRATHEDQKFKKVKECSSELKYSMEL 660

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
capu	NP_001137784.1	FH2	888..1315	CDD:214697	53/250 (21%)
FAM47A	NP_981953.2	FAM47	1..258	CDD:405345	53/274 (19%)
		PTZ00449	<176..584	CDD:185628	89/483 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	195..257		15/100 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	274..409		27/139 (19%)
		FAM47	<423..538	CDD:405345	25/130 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	449..573		32/141 (23%)