Protein Alignment Shaw and Kcnc4

DIOPT Version :10

• Sequence 1: NP_001137782.1
• Gene: Shaw / 33599
• FlyBaseID: FBgn0003386
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: XP_038959057.1
• Gene: Kcnc4 / 684516
• RGDID: 1589169
• Length: 663
• Species: Rattus norvegicus
• Alignment Length: 483
• Identity: 231/483 - (47%)
• Similarity: 306/483 - (63%)
• Gaps: 54/483 - (11%)

  Fly    22 DSENRVVLNVGGIRHETYKATLKKIPATRLSRLTEALANYDPILN----------------EYFF 70
            ::..::::||||.|||||::||:.:|.|||:.|.:......|..:                |:||
  Rat    33 EASEKIIINVGGTRHETYRSTLRTLPGTRLAWLADPDGGGRPESDGGGAGSSGSSGGGGGCEFFF 97

  Fly    71 DRHPGVFAQVLNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTQHRDTQETLAVL 135
            ||||||||.|||||||||||.|.|||||||||||.|||:|...|||||||||.||||.:|.|.:.
  Rat    98 DRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELTFWGIDETDVEPCCWMTYRQHRDAEEALDIF 162

  Fly   136 DRLD--------LDTEKPSEEELA-RKFGFEE-----DYYKGTISWWQEMKPRIWSLFDEPYSSN 186
            :..|        .|.....|.||| ::.|..|     ....|....||   ||:|:||::||||.
  Rat   163 ESPDGGGGGAGPGDEAGDDERELALQRLGPHEGGSGPGAGSGGCRGWQ---PRMWALFEDPYSSR 224

  Fly   187 AAKTIGVVSVFFICISILSFCLKTHPDMRVPIVRNITV--KTANGSNGWFLDKTQTNAHIAFFYI 249
            ||:.:...|:|||.:||.:|||:||....:.  ||:|.  :..|.::..|..:.:|...:.  ||
  Rat   225 AARVVAFASLFFILVSITTFCLETHEAFNID--RNVTEIHRVGNITSVRFRREVETEPILT--YI 285

  Fly   250 ECVCNAWFTFEILVRFISSPNKWEFIKSSVNIIDYIATLSFYIDLVLQRFASHLENADILEFFSI 314
            |.||..|||.|.|||.:..|:..:|:|:.:||||::|.|.||:::.|...:|.... |:|.|..:
  Rat   286 EGVCVMWFTLEFLVRIVCCPDTLDFVKNLLNIIDFVAILPFYLEVGLSGLSSKAAR-DVLGFLRV 349

  Fly   315 ---IRIMRLFKLTRHSSGLKILIQTFRASAKELTLLVFFLVLGIVIFASLVYYAERI-------Q 369
               :||:|:||||||..||::|..|.|||..|..||:.||.||::|||:::||||||       :
  Rat   350 VRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGARPSDPR 414

  Fly   370 PNPHNDFNSIPLGLWWALVTMTTVGYGDMAPKTYIGMFVGALCALAGVLTIALPVPVIVSNFAMY 434
            .|.|.||.:||:|.|||:|||||:|||||.|||:.||.||||||||||||||:||||||:||.||
  Rat   415 GNDHTDFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMY 479

  Fly   435 YSHTQARAKLPKKRRRVLPVEQPRQPRL 462
            ||...|:.||||||::    ..||.|:|
  Rat   480 YSLAMAKQKLPKKRKK----HVPRPPQL 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shaw	NP_001137782.1	BTB_Shaw-like	24..135	CDD:349723	70/126 (56%)
		Ion_trans	188..439	CDD:459842	129/262 (49%)
		PRK14959	<418..>585	CDD:184923	27/45 (60%)
Kcnc4	XP_038959057.1	Potassium_chann	1..29	CDD:431870
		BTB_KCNC2_4	35..159	CDD:349722	69/123 (56%)
		Ion_trans	226..484	CDD:459842	129/262 (49%)