Protein Alignment Shaw and Sh

DIOPT Version :10

• Sequence 1: NP_001137782.1
• Gene: Shaw / 33599
• FlyBaseID: FBgn0003386
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: NP_728123.1
• Gene: Sh / 32780
• FlyBaseID: FBgn0003380
• Length: 655
• Species: Drosophila melanogaster
• Alignment Length: 479
• Identity: 175/479 - (36%)
• Similarity: 247/479 - (51%)
• Gaps: 100/479 - (20%)

  Fly    26 RVVLNVGGIRHETYKATLKKIPATRLSRLTEALANYDPILNEYFFDRHPGVFAQVLNYYRT-GKL 89
            |||:||.|:|.||...||.:.|.|.|......|..:||:.|||||||....|..:|.||:: |:|
  Fly    98 RVVINVSGLRFETQLRTLNQFPDTLLGDPARRLRYFDPLRNEYFFDRSRPSFDAILYYYQSGGRL 162

  Fly    90 HYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTQHRDTQETLAVLDRLDLDTEKPSEEELARKF 154
            ..|.:|...:|.||::|:.|.                                     ::...||
  Fly   163 RRPVNVPLDVFSEEIKFYELG-------------------------------------DQAINKF 190

  Fly   155 GFEEDYYKGTISWWQEMKP--------RIWSLFDEPYSSNAAKTIGVVSVFFICISILSFCLKTH 211
            ..:|.:.|      :|.:|        ::|.||:.|.||.||:.:.::|||.|.:||:.|||:|.
  Fly   191 REDEGFIK------EEERPLPDNEKQRKVWLLFEYPESSQAARVVAIISVFVILLSIVIFCLETL 249

  Fly   212 PDMRVPIVRNITVKTANGSNGWFLDKTQT-NAHIAFFYIECVCNAWFTFEILVRFISSPNKWEFI 275
            |:.:...|.|.|      :||..:::.:. :....||.||.:|..|||||:.|||::.|||..|.
  Fly   250 PEFKHYKVFNTT------TNGTKIEEDEVPDITDPFFLIETLCIIWFTFELTVRFLACPNKLNFC 308

  Fly   276 KSSVNIIDYIATLSFYIDLVL-------------------QRFASHLENADILEFFSIIRIMRLF 321
            :..:|:||.||.:.::|.|..                   .:.::...:..||....::|:.|:|
  Fly   309 RDVMNVIDIIAIIPYFITLATVVAEEEDTLNLPKAPVSPQDKSSNQAMSLAILRVIRLVRVFRIF 373

  Fly   322 KLTRHSSGLKILIQTFRASAKELTLLVFFLVLGIVIFASLVYYAERIQPNPHNDFNSIPLGLWWA 386
            ||:|||.||:||.:|.:||.:||.||:|||.:|:|:|:|.||:||....|  :.|.|||...|||
  Fly   374 KLSRHSKGLQILGRTLKASMRELGLLIFFLFIGVVLFSSAVYFAEAGSEN--SFFKSIPDAFWWA 436

  Fly   387 LVTMTTVGYGDMAPKTYIGMFVGALCALAGVLTIALPVPVIVSNFAMYYSHTQARAKLPKKRRRV 451
            :|||||||||||.|....|..||:|||:|||||||||||||||||..:|            .|..
  Fly   437 VVTMTTVGYGDMTPVGVWGKIVGSLCAIAGVLTIALPVPVIVSNFNYFY------------HRET 489

  Fly   452 LPVEQPRQ--------PRLPGAPG 467
            ...|...|        |.|||..|
  Fly   490 DQEEMQSQNFNHVTSCPYLPGTLG 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shaw	NP_001137782.1	BTB_Shaw-like	24..135	CDD:349723	37/109 (34%)
		Ion_trans	188..439	CDD:459842	117/270 (43%)
		PRK14959	<418..>585	CDD:184923	23/58 (40%)
Sh	NP_728123.1	BTB_POZ	97..223	CDD:453885	47/167 (28%)
		Ion_trans	226..488	CDD:459842	117/281 (42%)