Protein Alignment Shaw and LOC1277769

DIOPT Version :10

• Sequence 1: NP_001137782.1
• Gene: Shaw / 33599
• FlyBaseID: FBgn0003386
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: XP_061513689.1
• Gene: LOC1277769 / 1277769
• VectorBaseID: AGAMI1_010466
• Length: 661
• Species: Anopheles gambiae
• Alignment Length: 624
• Identity: 350/624 - (56%)
• Similarity: 399/624 - (63%)
• Gaps: 120/624 - (19%)

  Fly    21 MDSENRVVLNVGGIRHETYKATLKKIPATRLSRLTEALANYDPILNEYFFDRHPGVFAQVLNYYR 85
            ||.|||::|||||||:|||||||||||||||||||||||||||:|||||||||||||||||||||
Mosquito     1 MDGENRIILNVGGIRYETYKATLKKIPATRLSRLTEALANYDPVLNEYFFDRHPGVFAQVLNYYR 65

  Fly    86 TGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTQHRDTQETLAVLDRLDLDTEKPSEEEL 150
            ||||||||||||||||||||||||||||||||||.||:.|||||.|||:||:|:||.|:||||.:
Mosquito    66 TGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWSTYSVHRDTQSTLAILDKLELDDEQPSEEAI 130

  Fly   151 ARKFGFEEDYYKGTISWWQEMKPRIWSLFDEPYSSNAAKTIGVVSVFFICISILSFCLKTHPDMR 215
            ||.|||||....|.::.||..||:||:|||||.||..||.:..:||||||||::||||||||.:|
Mosquito   131 ARLFGFEEALLNGELTCWQRTKPKIWALFDEPSSSTGAKIVAGISVFFICISVISFCLKTHPGLR 195

  Fly   216 V--PIVRNITVK---------------------------------TANGSNGWFLDKTQTNA--- 242
            |  |.:.|||..                                 |..|:.......|.|:|
Mosquito   196 VEIPAILNITTNGSASVLPDGLPTTLDELLDHGRLDELLLDYGAPTGTGTGSTSTTTTTTSATTE 260

  Fly   243 ---------------------------------------------HIAFFYIECVCNAWFTFEIL 262
                                                         |.||||:|.|||.||..|:.
Mosquito   261 SHSASPTRPETTTQRTGRIVSSAYRMNSGKGASIVENWQETYGQPHEAFFYVELVCNVWFIIELT 325

  Fly   263 VRFISSPNKWEFIKSSVNIIDYIATLSFYIDLVLQRFASHLENADILEFFSIIRIMRLFKLTRHS 327
            ||.:.:||.:|||||.|||||..||||||.| |.||..   |...:||.|||:||:|||||||||
Mosquito   326 VRLVVAPNIFEFIKSPVNIIDLAATLSFYTD-VCQRMG---EQTGLLEAFSIVRILRLFKLTRHS 386

  Fly   328 SGLKILIQTFRASAKELTLLVFFLVLGIVIFASLVYYAERIQPNPHNDFNSIPLGLWWALVTMTT 392
            .||:|||.||:|||:||||||||||||||:|||||||||::|.||.|.|.|||||||||:|||||
Mosquito   387 PGLRILIHTFKASARELTLLVFFLVLGIVVFASLVYYAEKLQDNPDNQFKSIPLGLWWAIVTMTT 451

  Fly   393 VGYGDMAPKTYIGMFVGALCALAGVLTIALPVPVIVSNFAMYYSHTQARAKLPKKRRRVLPVEQP 457
            |||||||||||:|||||||||||||||||||||||||||:|:|||||||:|||||||||||||||
Mosquito   452 VGYGDMAPKTYVGMFVGALCALAGVLTIALPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEQP 516

  Fly   458 RQPRLPGAPGGVSGCGTPGSGPHSGPMGSGGTGPRRMNNKTKDLVSPKSVAQLFAGPLGASIVAM 522
            |:.|                        ..|...||:|........|...| :|....|.:.:.
Mosquito   517 RRKR------------------------DMGVANRRVNALKHQHTQPTHPA-IFKDAFGGAKIG- 555

  Fly   523 SPRTMLDLNPALAMGKPTFQPRIPTPLAATPPPPVSSAG 561
                  .:|....:|.....|.:| .||...||.|...|
Mosquito   556 ------HVNGVNVIGLTLQGPSVP-GLAVLKPPAVLQQG 587

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shaw	NP_001137782.1	BTB_Shaw-like	24..135	CDD:349723	102/110 (93%)
		Ion_trans	188..439	CDD:459842	176/333 (53%)
		PRK14959	<418..>585	CDD:184923	57/144 (40%)
LOC1277769	XP_061513689.1	None